Clinical Trials Updated in 2025

NCT05438264 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

50 participants

Effect of Donepezil on Speech Recognition in Cochlear Implant Users

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2023-03-10
Completion:: 2026-09-01

Conditions

Bilateral Sensorineural Hearing Loss

Interventions

DRUG

No Results Yet

NCT05413759 | RECRUITING | NA

200 participants

RhEumatoid Arthritis MEDIcation Adherence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-06-28
Completion:: 2026-12-28

Conditions

Rheumatoid Arthritis

Interventions

OTHER

No Results Yet

NCT05409846 | COMPLETED

409 participants

Screening of Fabry Disease in Portuguese Patients With Idiopathic Cardiomyopathies

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-04-15
Completion:: 2025-01-01

Conditions

Fabry Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05399602 | COMPLETED | NA

41 participants

The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2023-12-07
Completion:: 2025-09-27

Conditions

Hydrocephalus
Brain Damage
General Anesthetics Toxicity

Interventions

DIAGNOSTIC_TEST
PROCEDURE

No Results Yet

NCT05396352 | RECRUITING | NA

80 participants

Cerebellum and Autism: Regional Specialization for Social and Executive Functions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-01-01
Completion:: 2025-12-31

Conditions

Autism
Autism Spectrum Disorder

Interventions

DEVICE

No Results Yet

NCT05386888 | COMPLETED | PHASE2

65 participants

A Trial of GFH018 and Toripalimab in Combination With Concurrent Chemoradiotherapy in Stage III NSCLC Chemoradiotherapy in Stage III NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-09-09
Completion:: 2023-12-31

Conditions

NSCLC, Stage III

Interventions

DRUG
RADIATION

No Results Yet

NCT05385523 | COMPLETED | NA

70 participants

Dexamedatomidine vs. Dexamethasone in Rhomboidal Intercostal Plain Block and Subserratus Block in Breast Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-07-20
Completion:: 2023-04-01

Conditions

Postoperative Pain, Acute

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05384054 | COMPLETED

150 participants

Association Between Erythroferron and Perioperative Hemoglobin Levels in Patient Undergoing Heart Valve Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-06-23
Completion:: 2024-11-15

Conditions

Postoperative Anemia

No Results Yet

NCT05346848 | RECRUITING | PHASE2

62 participants

Randomized Phase II Trial on Short Term Darolutamide Concomitant to Radiation Therapy for Patients With Intermediate Unfavorable Risk Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2023-02-24
Completion:: 2026-12-31

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT05332236 | COMPLETED

2338 participants

Parent-adolescent Communication: Validation of a German Language Scale and Its Longitudinal Association With Adolescent Mental Health

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-05-20
Completion:: 2024-12-31

Conditions

Parent-Child Relations

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05326035 | TERMINATED | PHASE1/PHASE2

26 participants

A Study of WJ05129 in Advanced Malignant Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-04-19
Completion:: 2023-12-26

Conditions

Locally Advanced or Metastatic Malignant Solid Tumors

Interventions

DRUG

No Results Yet

NCT05296564 | RECRUITING | PHASE1/PHASE2

3 participants

Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-04-01
Completion:: 2027-12-30

Conditions

Sarcoma, Synovial
Sarcoma,Soft Tissue
Melanoma Stage IV
Triple Negative Breast Cancer
Metastatic Cancer
Non Small Cell Lung Cancer
Bladder Urothelial Carcinoma
Neuroblastoma, Metastatic
Ovary Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05285111 | RECRUITING | NA

200 participants

Pilot of Reconnecting to Internal Sensations and Experiences in Undergraduates

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-09-01
Completion:: 2026-05-31

Conditions

Suicidal Ideation
Eating Disorder Symptom

Interventions

BEHAVIORAL

No Results Yet

NCT05269212 | RECRUITING | NA

112 participants

Return to Work for Persistent Spinal Pain Syndrome Type II Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-05-10
Completion:: 2027-08-31

Conditions

Failed Back Surgery Syndrome
Spinal Cord Stimulation

Interventions

OTHER

No Results Yet

NCT05263492 | TERMINATED | PHASE2

4 participants

Study of Lenvatinib w/ Pembro in Black Participants w/Mismatch Repair-Prof Recurrent Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-04-01
Completion:: 2024-09-13

Conditions

Endometrial Cancer
Mismatch Repair-Proficient
Recurrent Endometrial Cancer

Interventions

DRUG

Results Available

NCT05249452 | COMPLETED

20 participants

Adding Azathioprine/Hydroxyurea Preconditioning to Alemtuzumab/TBI to Reduce Risk of Graft Failure in MSD HSCT in Adult SCD Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2018-03-08
Completion:: 2023-12-01

Conditions

Sickle Cell Disease

Interventions

OTHER

No Results Yet

NCT05240885 | RECRUITING

100 participants

Metabolic and Functional Consequences of Aging in Health and Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-03-04
Completion:: 2026-09-30

Conditions

Aging

Interventions

OTHER

No Results Yet

NCT05227183 | RECRUITING | NA

120 participants

Prevention of Suicidal Behavior Through the VIGILANS Protocol: the Restoration of Social Connection Hypothesis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2024-09-12
Completion:: 2027-03-13

Conditions

Suicidal Behaviour Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05216835 | COMPLETED | PHASE1

45 participants

Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-03-18
Completion:: 2024-08-30

Conditions

Relapsed or Refractory Classical Hodgkin Lymphoma

Interventions

DRUG

Results Available

NCT05211570 | RECRUITING | PHASE1/PHASE2

78 participants

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-06-01
Completion:: 2026-08-31

Conditions

Acute Myeloid Leukemia Refractory
Acute Myeloid Leukemia, in Relapse
Myelodysplastic Syndrome Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT05205746 | COMPLETED | PHASE2

158 participants

Phase II Study of AVX/COVID-12 Vaccine in Subjects With Prior SARS-CoV-2 Immunity Evidence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-11-23
Completion:: 2022-08-09

Conditions

SARS CoV 2 Infection

Interventions

BIOLOGICAL

No Results Yet

NCT05195593 | TERMINATED

1 participants

Spine Registration Using 3D Scanning - Arise

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-01-05
Completion:: 2023-06-30

Conditions

Spinal Fusion
Spondylolisthesis
Scoliosis
Sciatica

Interventions

DEVICE

No Results Yet

NCT05195580 | TERMINATED

2 participants

Spine Registration Using 3D Scanning

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-08-31
Completion:: 2021-11-02

Conditions

Spinal Fusion
Spinal Stenosis
Scoliosis
Spondylolisthesis

Interventions

DEVICE

No Results Yet

NCT05177068 | ACTIVE_NOT_RECRUITING | PHASE2

42 participants

Conversion Therapy of Fruquintinib in Combination With Sintilimab and SOX in Unresectable Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-05-13
Completion:: 2024-10-16

Conditions

Gastric Cancer

Interventions

DRUG

No Results Yet

NCT05169814 | RECRUITING | EARLY_PHASE1

40 participants

Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-10-09
Completion:: 2026-06-01

Conditions

Open Wound
Wound Heal

Interventions

DRUG
OTHER

No Results Yet

NCT05159466 | RECRUITING

30 participants

Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-11-15
Completion:: 2026-11-30

Conditions

Human Immunodeficiency Virus
End Stage Renal Disease

Interventions

PROCEDURE

No Results Yet

NCT05156580 | ACTIVE_NOT_RECRUITING

31080 participants

Tongzhou Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2016-07-01
Completion:: 2026-07-01

Conditions

Obesity
Hypertension

Interventions

OTHER

No Results Yet

NCT05142345 | COMPLETED | NA

286 participants

Care Transition Intervention for Hospitalized Patients With Advanced Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-12-15
Completion:: 2025-01-30

Conditions

Cancer
Follow-Up Care
Consultation, Remote
Advanced Cancer

Interventions

OTHER

No Results Yet

NCT05090800 | COMPLETED | PHASE2

10 participants

Contrast Enhanced Ultrasound for Renal Obstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-12-03
Completion:: 2025-09-23

Conditions

Kidney; Obstruction
Renal Obstruction

Interventions

DRUG

No Results Yet

NCT05087849 | COMPLETED | PHASE1/PHASE2

2 participants

Intralesional HPV Vaccine for Condylomata

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-04-15
Completion:: 2024-07-01

Conditions

Human Papilloma Virus
Warts
Warts, Genital
Condyloma
Condylomata Acuminata

Interventions

BIOLOGICAL

Results Available

NCT05070208 | COMPLETED

400 participants

Multicenter Retrospective Observatory of Patients With Acute Myeloid Leukemia to Core Binding Factor

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-09-22
Completion:: 2024-01-25

Conditions

Acute Myeloblastic Leukemia Core Binding Factor

Interventions

OTHER

No Results Yet

NCT05040815 | RECRUITING | PHASE2

45 participants

Inguinal Node Sparing Radiotherapy For Patients With Early Stage Anal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2023-05-11
Completion:: 2028-05-31

Conditions

Anal Canal Cancer

Interventions

RADIATION

No Results Yet

NCT05031026 | ACTIVE_NOT_RECRUITING | PHASE4

60 participants

Dexmedetomidine to Prevent Hepatic Ischemia-reperfusion Injury-induced Glycocalyx Degradation and Early Allograft Dysfunction in Liver Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2022-03-15
Completion:: 2025-12-15

Conditions

Liver Transplant; Complications

Interventions

DRUG

No Results Yet

NCT05018780 | COMPLETED | NA

76 participants

Muscle Energy Techniques and Sacral Manipulation on Pain, Functional Disability and Quality of Life

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-07-01
Completion:: 2022-07-31

Conditions

Sacroiliac Joint Dysfunction

Interventions

OTHER

No Results Yet

NCT05018338 | TERMINATED

1 participants

Brain-Shift Monitoring Using 3D Scanning

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2020-02-28
Completion:: 2020-02-28

Conditions

Craniotomy for Epilepsy and Malignant Tumor Removal

Interventions

DEVICE

No Results Yet

NCT04986033 | COMPLETED

135 participants

Association Between Vitamin D and Perioperative Hemoglobin Levels in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery: Role of Hepcidin

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-08-01
Completion:: 2024-07-15

Conditions

Coronary Artery Disease

No Results Yet

NCT04985604 | TERMINATED | PHASE2

23 participants

Tovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-07-15
Completion:: 2024-07-08

Conditions

Melanoma
Solid Tumor
CRAF Gene Amplification
RAF1 Gene Amplification
BRAF Gene Fusion
BRAF Fusion
CRAF Gene Fusion
CRAF Fusion
RAF1 Gene Fusion
RAF1 Fusion
Thyroid Cancer, Papillary
Spitzoid Melanoma
Pilocytic Astrocytoma
Pilocytic Astrocytoma, Adult
Non Small Cell Lung Cancer
Non-Small Cell Adenocarcinoma
Colorectal Cancer
Pancreatic Acinar Carcinoma
Spitzoid Malignant Melanoma
Bladder Cancer
Bladder Urothelial Carcinoma
MAP Kinase Family Gene Mutation
RAF Mutation

Interventions

DRUG

Results Available

NCT04978558 | COMPLETED

509 participants

NIRS vs TCD for Cerebrovascular Autoregulation During Non-cardiac Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-08-09
Completion:: 2023-09-29

Conditions

Cerebrovascular Circulation

Interventions

OTHER

No Results Yet

NCT04976335 | RECRUITING | NA

50 participants

Quantitative and Clinical Assessment of Flexor Tendon Gliding Following Application of a Bioresorbable Hydrogel: A Prospective, Randomized Study in Patients Undergoing Distal Radius Fracture Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-09-13
Completion:: 2027-07-31

Conditions

Distal Radius Fracture
Tendon Rupture

Interventions

DEVICE

No Results Yet

NCT04914897 | TERMINATED | PHASE2

106 participants

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-02
Start Date:: 2021-09-23
Completion:: 2023-07-18

Conditions

Pleural Mesothelioma
Non-small Cell Lung Cancer

Interventions

DRUG

Results Available