Clinical Trials

NCT05433961 | TERMINATED | PHASE1

27 participants

Functional and Structural Assessment of Endobronchial Valve Recipients Using Dynamic Hyperpolarized Xenon-129 MRI

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2023-10-20

Completion:

2025-09-11

Conditions

• COPD

Interventions

• DRUG

No Results Yet

NCT05423977 | ENROLLING_BY_INVITATION | PHASE1

36 participants

Study of ZV0203 in Patients With HER2-Positive Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-12-17

Completion:

2023-05-05

Conditions

• HER2-positive Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05412927 | RECRUITING

500 participants

AngelMed Guardian® System PMA Post Approval Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-30

Start Date:

2022-09-07

Completion:

2026-12-31

Conditions

• Acute Coronary Syndrome

Interventions

• DEVICE

No Results Yet

NCT05406414 | COMPLETED | NA

88 participants

The Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Patients With Mental Disorders and Sleep Problems

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-05-23

Completion:

2024-05-30

Conditions

• Depression
• Bipolar Affective Disorder
• Attention Deficit Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05395390 | COMPLETED | NA

72 participants

COPD Circuit Exercise

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-02-02

Completion:

2023-08-07

Conditions

• OSA
• Covid19
• Residual Symptoms of COVID 19
• COPD

Interventions

• BEHAVIORAL

No Results Yet

NCT05382494 | COMPLETED | PHASE4

130 participants

Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-12-05

Completion:

2025-07-17

Conditions

• Sleep Disorder; Breathing-Related
• Snoring
• Obstructive Sleep Apnea of Child
• Sleep Disorders in Children
• Tonsillar Hypertrophy
• Adenoidal Disorder

Interventions

• DRUG

No Results Yet

NCT05372861 | RECRUITING

20 participants

Nanopore Sequencing in Ophthalmology

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-30

Start Date:

2022-04-22

Completion:

2026-12-01

Conditions

• Endophthalmitis

No Results Yet

NCT05370976 | TERMINATED | PHASE2

2 participants

Efficacy and Safety of Cytotect®CP, Hyperimmune Anti-CMV IVIg as CMV Prophylaxis in Patients Developing Acute Grade II-IV GVHD After Allogeneic Hematopoietic Cell Transplantation.

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-09-13

Completion:

2023-08-24

Conditions

• Cytomegalovirus Infections

Interventions

• DRUG

No Results Yet

NCT05358808 | TERMINATED | PHASE2

16 participants

ACHIEVE - Efficacy and Effectiveness of Adoptive Cellular tHerapy wIth Ex-Vivo Expanded Allogeneic γδ T-lymphocytes (TCB008) for Patients With Refractory or Relapsed Acute Myeloid Leukaemia (AML)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-08-15

Completion:

2025-07-30

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndromes

Interventions

• DRUG

No Results Yet

NCT05357443 | ACTIVE_NOT_RECRUITING | NA

50 participants

SH Dr. Chen Gastric Bypass Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-08-31

Completion:

2026-09-30

Conditions

• Gastric Bypass

Interventions

• PROCEDURE

No Results Yet

NCT05328752 | COMPLETED | PHASE1

27 participants

Safety and Tolerability Study of XXB750 in Heart Failure Participants With Reduced or Mildly Reduced Ejection Fraction (HFrEF/HFmrEF)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-05-17

Completion:

2024-01-18

Conditions

• Heart Failure With Reduced Ejection Fraction (HFrEF)
• or Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)

Interventions

• DRUG

No Results Yet

NCT05322460 | RECRUITING | NA

182 participants

Web-based Intervention for Long-term Breast Cancer Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2023-12-15

Completion:

2025-09-30

Conditions

• Long-term Effects of Cancer Treatment
• Long-term Effects Secondary to Cancer Therapy in Adults

Interventions

• OTHER

No Results Yet

NCT05319587 | COMPLETED | PHASE1/PHASE2

22 participants

Study of Liposomal Annamycin in Combination With Cytarabine for the Treatment of Subjects With Acute Myeloid Leukemia (AML)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-09-29

Completion:

2023-08-02

Conditions

• Leukemia, Myeloid, Acute

Interventions

• DRUG

No Results Yet

NCT05304351 | ACTIVE_NOT_RECRUITING | PHASE2

1516 participants

Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-02-02

Completion:

2026-06-30

Conditions

• Herpes Zoster
• Shingles

Interventions

• BIOLOGICAL

No Results Yet

NCT05296070 | RECRUITING | PHASE2

50 participants

Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-06-21

Completion:

2028-06-30

Conditions

• Marginal Zone Lymphoma

Interventions

• DRUG

No Results Yet

NCT05268640 | COMPLETED | NA

81 participants

Cervical Occlusion Double-level Stitch Application

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-03-11

Completion:

2025-03-10

Conditions

• Cervical Incompetence

Interventions

• PROCEDURE

No Results Yet

NCT05256901 | TERMINATED | PHASE4

22 participants

Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2023-07-19

Completion:

2024-07-05

Conditions

• Appendicitis
• Surgery

Interventions

• DRUG

Results Available

NCT05237401 | ACTIVE_NOT_RECRUITING | NA

59 participants

Non-surgical vs. Surgical Therapy for Periodontal Furcations

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-04-21

Completion:

2029-01-31

Conditions

• Furcation Defects
• Periodontitis
• Surgical Procedure, Unspecified

Interventions

• PROCEDURE

No Results Yet

NCT05190120 | COMPLETED | PHASE4

132 participants

Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2016-01-31

Completion:

2022-03-20

Conditions

• Anterior Cruciate Ligament Tear
• Knee Meniscus Tear

Interventions

• PROCEDURE
• DRUG

Results Available

NCT05181592 | ACTIVE_NOT_RECRUITING | PHASE3

70 participants

Assessment of Effectiveness and Safety of Luspatercept in Patients Suffering From Lower-risk Myelodysplastic Syndrome.

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-10-27

Completion:

2026-10-31

Conditions

• Myelodysplastic Syndromes

Interventions

• DRUG

No Results Yet

NCT05180448 | COMPLETED | NA

322 participants

Sharing Digital Self-Monitoring Data With Others to Enhance Long-Term Weight Loss

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-01-03

Completion:

2025-07-30

Conditions

• Overweight
• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT05168046 | COMPLETED | NA

21 participants

Mindfulness-based Intervention for People With Parkinsonian Tremor

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-11-15

Completion:

2024-10-20

Conditions

• Parkinson Disease
• Rest Tremor

Interventions

• BEHAVIORAL

No Results Yet

NCT05159960 | ENROLLING_BY_INVITATION | NA

400 participants

Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-01-10

Completion:

2027-12-31

Conditions

• Glaucoma, Open-Angle
• Pseudoexfoliation Glaucoma
• Ocular Hypertension

Interventions

• PROCEDURE

No Results Yet

NCT05152823 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

10 participants

Gene Therapy for IGHMBP2-Related Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-11-04

Completion:

2028-07-31

Conditions

• SMARD1
• CMT2S

Interventions

• BIOLOGICAL

No Results Yet

NCT05148546 | ACTIVE_NOT_RECRUITING | PHASE2

69 participants

Neoadjuvant Study With Combination Immuno-oncology for Primary Clear Cell Renal Cell Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-04-28

Completion:

2025-04-22

Conditions

• Renal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT05148234 | TERMINATED | PHASE1/PHASE2

2 participants

BMS-986253 in Myelodysplastic Syndromes

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-11-29

Completion:

2023-02-02

Conditions

• Myelodysplastic Syndromes

Interventions

• DRUG
• PROCEDURE

Results Available

NCT05121324 | RECRUITING | PHASE3

6700 participants

Pediatric Dose Optimization for Seizures in Emergency Medical Services

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-08-08

Completion:

2026-07-31

Conditions

• Seizures

Interventions

• DRUG

No Results Yet

NCT05089695 | RECRUITING | NA

1200 participants

Helmet NIV vs. CPAP vs. High-flow Nasal Oxygen in Hypoxemic Respiratory Failure

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-03-01

Completion:

2025-12-31

Conditions

• Respiratory Failure
• Hypoxemic Respiratory Failure

Interventions

• DEVICE

No Results Yet

NCT05051527 | COMPLETED

362 participants

Study to Evaluate the Effectiveness of Legalon®

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-30

Start Date:

2022-08-08

Completion:

2024-10-31

Conditions

• Non-alcoholic Fatty Liver Disease (NAFLD)

Interventions

• DRUG

No Results Yet

NCT05046834 | WITHDRAWN | NA

0 participants

Effect of Cold Application on Patient's Pain and Vital Signs During Chest Tube Removal.

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2026-10-15

Completion:

2026-10-15

Conditions

• Chest Tube Removal

Interventions

• OTHER

No Results Yet

NCT05046782 | WITHDRAWN | PHASE2

0 participants

Abbreviated Biparametric MRI (RSI + T2WI) for Prostate Cancer Detection: Correlation With Histopathology

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2026-02-28

Completion:

2027-02-02

Conditions

• Prostate Cancer

Interventions

• DEVICE

No Results Yet

NCT05036252 | ACTIVE_NOT_RECRUITING

23 participants

Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-30

Start Date:

2021-08-27

Completion:

2026-08-27

Conditions

• Breast Cancer
• HER2-positive Breast Cancer
• HER2-positive Metastatic Breast Cancer
• Breast Cancer Stage I
• Breast Cancer Stage II
• Breast Cancer Stage III
• Breast Cancer Stage IV
• Cardiotoxicity

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05012410 | COMPLETED | NA

262 participants

WeCareAdvisor Study for Caregivers of People Living With Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-12-13

Completion:

2024-07-19

Conditions

• Dementia
• Caregiver Burnout
• Caregiver Stress Syndrome
• Alzheimer Disease
• Frontotemporal Dementia
• Vascular Dementia
• Dementia With Lewy Bodies

Interventions

• BEHAVIORAL

No Results Yet

NCT04986670 | ACTIVE_NOT_RECRUITING | NA

299 participants

NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2020-11-24

Completion:

2024-12-31

Conditions

• Lung Cancer, Small Cell
• Lung Cancer Metastatic
• Lung Cancer Recurrent
• Treatment Side Effects
• Lung Cancer, Non-small Cell
• Nutritional Imbalance

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04984356 | COMPLETED | PHASE1

28 participants

A Phase 1 Study of of Anti-CD7 Allogeneic CAR-T Cell Therapy (WU-CART-007) in Patients With Relapsed or Refractory T-ALL/LBL

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2022-01-14

Completion:

2024-08-08

Conditions

• T-cell Acute Lymphoblastic Leukemia
• Lymphoblastic Lymphoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04972162 | COMPLETED | NA

28 participants

Fitting Strategy Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-07-26

Completion:

2021-11-12

Conditions

• Hearing Loss, Sensorineural

Interventions

• DEVICE

Results Available

NCT04941573 | TERMINATED

45 participants

Assessment of Chronic Lung Allograft Dysfunction Using Single-breath & Multi-breath Hyperpolarized Xenon-129 MRI

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-30

Start Date:

2021-01-19

Completion:

2025-09-04

Conditions

• Lung Transplant Rejection

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04908397 | COMPLETED | PHASE1

10 participants

Carnitine Consumption and Augmentation in Pulmonary Arterial Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-09-29

Completion:

2023-06-01

Conditions

• Pulmonary Arterial Hypertension
• Familial Primary Pulmonary Hypertension
• Primary Pulmonary Hypertension
• Lung Diseases
• Carnitine Nutritional Deficiency

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT04879628 | ACTIVE_NOT_RECRUITING | PHASE2

129 participants

Proof-of-concept Study for SAR441344 (Frexalimab) in Relapsing Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-06-07

Completion:

2022-09-21

Conditions

• Multiple Sclerosis

Interventions

• DRUG

Results Available

NCT04810052 | COMPLETED | NA

75 participants

Positive Activities Intervention to Improve Quality of Life in Collectivist Culture Cancer Patients and Their Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-30

Start Date:

2021-05-18

Completion:

2025-09-19

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm

Interventions

• BEHAVIORAL
• OTHER

No Results Yet