Clinical Trials Updated in 2025

NCT06656793 | COMPLETED

3597 participants

Impact of Real-Time Ultrasound-Guided Spinal Anesthesia Versus Landmark-Guided Spinal Anesthesia on Anesthesia Procedural Time

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-01-25
Completion:: 2025-01-25

Conditions

Spinal Anesthesia

No Results Yet

NCT06639464 | RECRUITING | PHASE2

46 participants

Semaglutide for Helping Opioid Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-06-02
Completion:: 2026-08-31

Conditions

Opioid Use Disorder

Interventions

DRUG
OTHER

No Results Yet

NCT06623136 | RECRUITING | PHASE2

40 participants

A Study of ES102 in Combination With Toripalimab in Subjects With Advanced Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-04-30
Completion:: 2027-02-28

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06616363 | RECRUITING

120 participants

Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-05-29
Completion:: 2028-07-31

Conditions

POTS - Postural Orthostatic Tachycardia Syndrome

Interventions

BEHAVIORAL
DEVICE
OTHER
DIAGNOSTIC_TEST

No Results Yet

NCT06605014 | RECRUITING

120 participants

Somatic Dysfunction in Patients With Acute Cerebrovascular Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-09-01
Completion:: 2026-06-30

Conditions

Stroke, Acute
TIA
Reproducibility of Results
Osteopathic Manipulation
Health-Related Quality-of-Life

No Results Yet

NCT06597773 | WITHDRAWN | NA

0 participants

Online Patient Navigation Program for Patients With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-09-21
Completion:: 2025-09-22

Conditions

Breast Cancer
Supportive Care in Cancer
Patient Navigation

Interventions

OTHER

No Results Yet

NCT06597474 | RECRUITING | PHASE2/PHASE3

800 participants

Food-Body-Mind Intervention (16 Weeks)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-08-14
Completion:: 2028-07-31

Conditions

Mental Health Wellness
Emotional Problem
Behavioral Problem of Child
Social Skills
Obesity, Childhood

Interventions

BEHAVIORAL

No Results Yet

NCT06576089 | RECRUITING | NA

120 participants

Optimizing Recruitment to Drive Equitable Research Opportunity in Stroke Rehabilitation Trials in Canada

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-06-16
Completion:: 2027-06-30

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT06564506 | NOT_YET_RECRUITING | NA

1460 participants

Electroacupuncture for Preventing Postoperative Delirium in Older Adults Undergoing Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-11-10
Completion:: 2026-08-30

Conditions

Postoperative Delirium

Interventions

DEVICE

No Results Yet

NCT06556407 | RECRUITING | NA

12 participants

Effect of Renal Denervation on Bood Pressure in Patients on Hemodialysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-03-04
Completion:: 2026-12-01

Conditions

Treatment Resistant Hypertension
Chronic Hemodialysis

Interventions

DEVICE

No Results Yet

NCT06540391 | ACTIVE_NOT_RECRUITING | PHASE1

41 participants

A Phase 1b Trial to Evaluate Safety of MB097 in Combination With Pembrolizumab in Melanoma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-08-28
Completion:: 2025-12-31

Conditions

Melanoma

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06527937 | COMPLETED | PHASE2

36 participants

Pharmacokinetics Study of DESF in Adults With Oral Allergy Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-07-17
Completion:: 2024-10-10

Conditions

Allergic Reaction

Interventions

DRUG

No Results Yet

NCT06493357 | RECRUITING | NA

2426 participants

Evaluation of a Differentiated Point-of-care Active Case Finding & Management Model to Eliminate Mother-to-Child Transmission of HIV in Malawi

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-03-27
Completion:: 2028-01-31

Conditions

HIV Prevention

Interventions

BEHAVIORAL

No Results Yet

NCT06477250 | ACTIVE_NOT_RECRUITING | NA

200 participants

Investigating the Effects of a Dyad Intervention on Teacher Resilience, Mental Health, and Social Emotions and Behavior

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-06-20
Completion:: 2025-12-31

Conditions

Burnout

Interventions

BEHAVIORAL

No Results Yet

NCT06472102 | RECRUITING | NA

100 participants

Cardioneuroablation: Fragmented Atrial Potentials, Intracardiac Echocardiography and Computed Tomography

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-05-20
Completion:: 2025-12-31

Conditions

Syncope, Vasovagal

Interventions

PROCEDURE

No Results Yet

NCT06445764 | WITHDRAWN | NA

0 participants

Traumatic Cardiac Arrest and Trauma SimVR Training

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-09-01
Completion:: 2026-08-30

Conditions

Virtual Reality
Heart Arrest

Interventions

OTHER

No Results Yet

NCT06440291 | RECRUITING | NA

100 participants

Cardioneuroablation for Reflex Syncope and Exercise Capacity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-05-02
Completion:: 2025-12-01

Conditions

Syncope, Vasovagal

Interventions

PROCEDURE

No Results Yet

NCT06431048 | ENROLLING_BY_INVITATION | NA

120 participants

No DIET Trial: Dogmatic Interruption of Enteral nuTrition

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-06-25
Completion:: 2027-06-30

Conditions

Gastrostomy
Tracheostomy

Interventions

OTHER

No Results Yet

NCT06429059 | COMPLETED | PHASE2

50 participants

ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-06-12
Completion:: 2025-05-22

Conditions

Amyotrophic Lateral Sclerosis ALS

Interventions

DRUG

No Results Yet

NCT06420518 | COMPLETED

16 participants

Accuracy of a Continuous Ketone Monitoring (CKM) System in Individuals With Type 1 Diabetes on Insulin Pump Therapy.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-04-30
Completion:: 2025-02-18

Conditions

type1diabetes

Interventions

OTHER

No Results Yet

NCT06398457 | RECRUITING | EARLY_PHASE1

8 participants

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-09-19
Completion:: 2026-09-30

Conditions

Hematologic Malignancy
Bone Marrow Transplant Rejection
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndromes (MDS)
Acute Lymphoblastic Leukemia (ALL), Adult
Multiple Myeloma
Aplastic Anemia
Lymphoma
Non Hodgkin Lymphoma
Hodgkin Lymphoma
Chronic Myeloid Leukemia
Myelofibrosis

Interventions

DRUG
DEVICE

No Results Yet

NCT06393387 | COMPLETED

800 participants

Retrospective Review of DTG/3TC Versus BIC/F/TAF Across a Multi Clinic Infectious Disease Organization in Southeast United States

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-06-01
Completion:: 2025-04-01

Conditions

Hiv
HIV-1-infection
HIV Infections

Interventions

DRUG

No Results Yet

NCT06387355 | WITHDRAWN | NA

0 participants

Diagnosis and Treatment of CAD in Severe PAD After Lower Extremity Revascularization

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-11-01
Completion:: 2024-11-01

Conditions

Peripheral Artery Disease
Coronary Artery Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06385249 | COMPLETED | NA

27 participants

An Evaluation of Navina Mini, a New Trans-anal Irrigation (TAI) Device in Children and Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-04-03
Completion:: 2025-07-09

Conditions

Bowel Dysfunction

Interventions

DEVICE

No Results Yet

NCT06358638 | RECRUITING | PHASE2

12 participants

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-04-03
Completion:: 2044-09-30

Conditions

Sickle Cell Disease

Interventions

DRUG
RADIATION

No Results Yet

NCT06332963 | RECRUITING | NA

102 participants

Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-04-19
Completion:: 2028-06-30

Conditions

Anorexia Nervosa
Body Image Disturbance
Interoception

Interventions

BEHAVIORAL

No Results Yet

NCT06326697 | COMPLETED | PHASE1

32 participants

Bioequivalence of Azacitidine 300 mg Film-Coated Tablets in Adult Patients With Acute Myeloid Leukaemia (AML)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-05-02
Completion:: 2025-08-17

Conditions

Acute Myeloid Leukaemia

Interventions

DRUG

No Results Yet

NCT06320067 | RECRUITING | PHASE3

3360 participants

A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-06-11
Completion:: 2031-04-30

Conditions

Prostate Cancer Metastatic

Interventions

RADIATION
OTHER
DRUG

No Results Yet

NCT06318390 | COMPLETED | NA

6 participants

The Impact of KETO5 XOGenius Beverage on Markers of Physiological and Neurocognitive Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-08-01
Completion:: 2025-05-15

Conditions

Cardiovascular Diseases
Hypertension
Cognitive Decline
Diet
Healthy

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06299709 | COMPLETED | PHASE1

34 participants

A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulation of Vanzacaftor/Tezacaftor/Deutivacaftor(VNZ/TEZ/D-IVA)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-03-13
Completion:: 2024-05-23

Conditions

Cystic Fibrosis

Interventions

DRUG

No Results Yet

NCT06291922 | RECRUITING | NA

100 participants

Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-08-14
Completion:: 2028-06-30

Conditions

Heart Failure

Interventions

BEHAVIORAL

No Results Yet

NCT06291675 | RECRUITING

50 participants

Gender-Affirming Hormone Therapy and Its Impact on Myocardial Mass and Cardiac Function, Heart, Liver and Pancreatic Fat Content

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-03-03
Completion:: 2027-03-03

Conditions

Gender Dysphoria
Hormone Therapy Induced Morphologic Change

Interventions

DRUG

No Results Yet

NCT06283290 | COMPLETED

201 participants

PROPE Severe Asthma Study in Egypt

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-03-12
Completion:: 2024-11-28

Conditions

Severe Asthma

No Results Yet

NCT06281821 | COMPLETED | NA

32 participants

Mobile App-based Approach for Reducing Pain and Hazardous Drinking: a Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-02-06
Completion:: 2024-10-31

Conditions

Alcohol Drinking
Chronic Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06265272 | RECRUITING

45 participants

Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-12-10
Completion:: 2026-12-19

Conditions

Liver Cirrhosis
Hepatic Cell Carcinoma
Portal Hypertension

Interventions

DRUG
DIAGNOSTIC_TEST

No Results Yet

NCT06241898 | RECRUITING | PHASE1

300 participants

A First-in-human of Multiplle Doses of BB-1709 in Subjects With Locally Advanced/Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-10-01
Completion:: 2026-06-30

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06215066 | COMPLETED | NA

158 participants

Effect of Virtual Reality and Progressive Muscle Relaxation on Anxiety and Attention Among Cardiac Care Unit Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-04-20
Completion:: 2025-05-20

Conditions

Anxiety

Interventions

DEVICE
OTHER

No Results Yet

NCT06209463 | COMPLETED

80 participants

Posture, Hand Functions and Sensory Processing Skills on Nutrition

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-11-20
Completion:: 2024-03-20

Conditions

Autism Spectrum Disorder
Autism
Autism, Mild
ASD

No Results Yet

NCT06176001 | COMPLETED | NA

206 participants

Group-based Psychoeducation for Relatives of Patients With Bipolar Disorder, a Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-04-07
Completion:: 2024-06-01

Conditions

Bipolar Disorder

Interventions

OTHER

No Results Yet

NCT06169722 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

60 participants

TDI01 Suspension in the Treatment of Chronic Graft-versus-host Disease (cGVHD))

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2024-02-06
Completion:: 2026-02-28

Conditions

GVHD, Chronic

Interventions

DRUG

No Results Yet