Clinical Trials

NCT05109611 | TERMINATED | PHASE3

1389 participants

Nitric Oxide Nasal Spray (NONS) as Prevention for Treatment of Individuals at Risk of Exposure to COVID-19 Infection

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-11-20

Completion:

2024-01-30

Conditions

• SARS-CoV-2 Infection

Interventions

• DRUG
• DEVICE

Results Available

NCT05102760 | ACTIVE_NOT_RECRUITING | NA

80 participants

PENG vs. FIC Block for Hip Fracture ED Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-10-20

Completion:

2026-06-30

Conditions

• Pain
• Hip Fracture

Interventions

• PROCEDURE

No Results Yet

NCT05081024 | RECRUITING

50 participants

Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2021-09-03

Completion:

2026-09-03

Conditions

• Rectal Adenocarcinoma
• Stage II Rectal Cancer AJCC v8
• Stage IIA Rectal Cancer AJCC v8
• Stage IIB Rectal Cancer AJCC v8
• Stage IIC Rectal Cancer AJCC v8
• Stage III Rectal Cancer AJCC v8
• Stage IIIA Rectal Cancer AJCC v8
• Stage IIIB Rectal Cancer AJCC v8
• Stage IIIC Rectal Cancer AJCC v8

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05078957 | RECRUITING

132 participants

Microbiota Footprint and Frailty Phenotype in Virologically Suppressed People Living With HIV

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2023-12-05

Completion:

2030-03-31

Conditions

• HIV Infections

Interventions

• OTHER

No Results Yet

NCT05063708 | COMPLETED | NA

136 participants

Neuromuscular Electrostimulation in Multiple Sclerosis People With Dysphagia

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2022-01-21

Completion:

2023-04-15

Conditions

• Deglutition Disorders
• Multiple Sclerosis

Interventions

• DEVICE

No Results Yet

NCT05057234 | ACTIVE_NOT_RECRUITING | NA

1500 participants

PRecision Oncology Evidence Development in Cancer Treatment - Liquid

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-06-18

Completion:

2027-06-01

Conditions

• Cancer

Interventions

• DIAGNOSTIC_TEST
• BEHAVIORAL

No Results Yet

NCT05037331 | RECRUITING

58 participants

Osimertinib for Advanced EGFR-positive NSCLC Patients

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2021-07-22

Completion:

2026-06-30

Conditions

• EGFR Positive Non-small Cell Lung Cancer
• Non Small Cell Lung Cancer

No Results Yet

NCT04954183 | COMPLETED

29 participants

Development of an EEG Diagnostic for Alzheimer's Disease

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2021-10-01

Completion:

2025-07-24

Conditions

• Mild Cognitive Impairment
• Alzheimer Disease
• Dementia With Lewy Bodies
• Normal Control APOE e4 Carriers and Noncarriers

No Results Yet

NCT04927832 | COMPLETED | NA

139 participants

Detection of Small Fiber Neuropathies by the Non-invasive SUDOSCAN Method During Chronic Autoimmune Pathologies and / or Unexplained Pain Syndromes

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2017-07-06

Completion:

2023-02-23

Conditions

• Systemic Autoimmune Pathologies
• Unexplained Pain Syndrome

Interventions

• OTHER

No Results Yet

NCT04925960 | TERMINATED | PHASE3

42 participants

Oral Epalrestat Therapy in Pediatric Subjects With PMM2-CDG

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2022-11-10

Completion:

2025-02-28

Conditions

• Pmm2-CDG
• Phosphomannomutase 2 Deficiency
• Phosphomannomutase 2 Congenital Disorder of Glycosylation
• Phosphomannomutase II Congenital Disorder of Glycosylation
• Phosphomannomutase II Deficiency

Interventions

• DRUG

No Results Yet

NCT04917861 | COMPLETED | PHASE2

808 participants

A Study of Zika Vaccine mRNA-1893 in Adult Participants Living in Endemic and Non-Endemic Flavivirus Areas

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-06-07

Completion:

2024-07-26

Conditions

• Zika Virus

Interventions

• BIOLOGICAL

Results Available

NCT04899154 | RECRUITING | NA

80 participants

Analysis of Intestinal Microbiota as a Predictor of Response to Treatment of Spondyloarthritis With Biotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2019-07-16

Completion:

2026-05-15

Conditions

• Spondyloarthritis

Interventions

• OTHER

No Results Yet

NCT04886895 | RECRUITING | NA

35 participants

Motor Training for Infants With Cerebral Palsy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2022-01-07

Completion:

2027-01-01

Conditions

• Cerebral Palsy

Interventions

• OTHER

No Results Yet

NCT04875702 | RECRUITING | PHASE4

650 participants

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2024-02-22

Completion:

2028-09-01

Conditions

• Gout

Interventions

• DRUG

No Results Yet

NCT04859205 | COMPLETED | NA

229 participants

The SUPPORT-Pro Online Platform for Healthcare Professionals Treating Individuals Living With T1D

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-05-13

Completion:

2022-12-20

Conditions

• Educational Activities

Interventions

• BEHAVIORAL

No Results Yet

NCT04850755 | COMPLETED | PHASE1

11 participants

A Phase I Dose Escalation Study of Selinexor Plus Nivolumab and Ipilimumab in Advanced/Metastatic Solid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-03-08

Completion:

2025-03-17

Conditions

• Advance Solid Malignancies
• Metastatic Solid Malignancies

Interventions

• DRUG

No Results Yet

NCT04826692 | COMPLETED | PHASE3

60 participants

TEsting METformin Against Cognitive Decline in HD

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2022-04-11

Completion:

2025-06-10

Conditions

• Huntington Disease

Interventions

• DRUG

No Results Yet

NCT04814095 | RECRUITING | NA

30 participants

PRecision Oncology Evidence Development in Cancer Treatment - Clinical: PREDiCTc

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-06-30

Completion:

2028-05-01

Conditions

• Cancer

Interventions

• BEHAVIORAL
• DIAGNOSTIC_TEST

No Results Yet

NCT04770935 | COMPLETED | PHASE1

6 participants

To Assess the Pharmacokinetics and Safety and Tolerability of Efanesoctocog Alfa (BIVV001)in Adults With Type 2N and 3 Von Willebrand Disease (VWD)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-05-03

Completion:

2022-12-01

Conditions

• Von Willebrand's Disease (VWD)

Interventions

• DRUG

No Results Yet

NCT04768686 | COMPLETED | PHASE2

20 participants

FLX475 Combined With Pembrolizumab in Patients With Advanced or Metastatic Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-05-18

Completion:

2024-08-12

Conditions

• Gastric Cancer

Interventions

• DRUG

Results Available

NCT04743960 | COMPLETED | NA

20 participants

Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-10-05

Completion:

2022-10-24

Conditions

• Feeding Patterns
• Sleep
• Glucose Intolerance
• Short Bowel Syndrome

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04710043 | COMPLETED | PHASE1

86 participants

Dose Escalation Trial of BNT152+153 in Patients With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-06-08

Completion:

2025-09-10

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT04694248 | RECRUITING | NA

172 participants

Anticoagulant Plus Antiplatelet Therapy Following Iliac Vein Stenting

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-11-03

Completion:

2026-12-31

Conditions

• Deep Vein Thrombosis
• Iliac Vein Thrombosis
• Iliac Vein Obstruction
• Iliac Vein Stenosis
• Iliac Vein Compression Syndrome

Interventions

• DRUG

No Results Yet

NCT04682145 | ENROLLING_BY_INVITATION

50 participants

Adverse Event Data Collection From the EUHASS Registry on Turoctocog Alfa Pegol

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2020-12-09

Completion:

2026-02-01

Conditions

• Haemophilia A

Interventions

• DRUG

No Results Yet

NCT04681131 | COMPLETED | PHASE2

85 participants

CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-03-17

Completion:

2025-07-09

Conditions

• Non-Small-Cell Lung Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT04602260 | COMPLETED

211 participants

Functional Recovery of Hospitalised Patients With COVID-19: The COREG Extension Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2020-06-09

Completion:

2024-01-08

Conditions

• Covid19
• Corona Virus Infection
• Mobility Limitation
• Frailty

No Results Yet

NCT04589247 | COMPLETED

104 participants

Improving Cancer On-treatment Symptom Management

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2020-11-16

Completion:

2023-07-23

Conditions

• Cancer
• Thoracic Neoplasms
• Gastrointestinal Cancer
• Lung Cancer

Results Available

NCT04585711 | WITHDRAWN | PHASE1

0 participants

Pharmacokinetics and Pharmacodynamics of Biologic Drugs in Obese Patients With Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2026-07-01

Completion:

2027-02-28

Conditions

• Juvenile Idiopathic Arthritis
• Rheumatoid Arthritis
• Obesity

Interventions

• DRUG

No Results Yet

NCT04582149 | COMPLETED | NA

30 participants

Eye-Control Trial: Wearable Eye-Tracking Device as Means of Communication

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-05-19

Completion:

2023-01-23

Conditions

• Acute Respiratory Failure Requiring Mechanical Ventilation

Interventions

• DEVICE

Results Available

NCT04578483 | COMPLETED

634 participants

Postoperative Pain Management of Therapeutic Surgery: a Prospective, Observational Cohort Study.

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2020-10-27

Completion:

2022-09-30

Conditions

• Postoperative Pain

Interventions

• OTHER

No Results Yet

NCT04523987 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

A Pilot Study of Ciprofloxacin Plus Gemcitabine and Nab-Paclitaxel Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2019-02-22

Completion:

2027-02-28

Conditions

• Metastatic Pancreatic Ductal Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT04520269 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

74 participants

A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2020-07-13

Completion:

2026-07-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04446962 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

118 participants

LOC-R01 Study of Lenalidomide and Ibrutinib in Association With Rituximab-Methotrexate Procarbazine Vincristin (R-MPV)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2020-10-30

Completion:

2035-02-02

Conditions

• Lymphoma, Large B-Cell, Diffuse
• Central Nervous System Neoplasms, Primary

Interventions

• DRUG

No Results Yet

NCT04423952 | WITHDRAWN

0 participants

Validity of the French Version of the Quality of Life Questionnaire COMQ12-FR

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2020-05-20

Completion:

2020-05-20

Conditions

• Chronic Otitis Media

Interventions

• OTHER

No Results Yet

NCT04417465 | COMPLETED | PHASE1

101 participants

First In Human Study With ABBV-CLS-579 When Given Alone and In Combination In Participants With Locally Advanced Or Metastatic Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2020-06-03

Completion:

2025-08-21

Conditions

• Advanced Solid Tumors Cancer

Interventions

• DRUG

No Results Yet

NCT04400539 | RECRUITING | PHASE2

20 participants

The IMmunotherapy Pleural 5-ALA PDT

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2022-05-09

Completion:

2026-05-09

Conditions

• Mesotheliomas Pleural
• Malignant Pleural Mesothelioma

Interventions

• DEVICE
• DRUG

No Results Yet

NCT04314752 | RECRUITING

4000 participants

Development of a Research Infrastructure for Understanding and Addressing Multiple Myeloma Disparities

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2020-09-01

Completion:

2026-05-30

Conditions

• Multiple Myeloma

No Results Yet

NCT04233138 | COMPLETED | NA

285 participants

SUPPORT Online Training Platform for Type 1 Diabetes Self-management Education and Support (SUPPORT)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2020-02-05

Completion:

2023-03-19

Conditions

• Type 1 Diabetes Mellitus With Hypoglycemia

Interventions

• OTHER

No Results Yet

NCT04190706 | COMPLETED | NA

62 participants

Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk Prevention

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2020-01-21

Completion:

2022-05-17

Conditions

• Cardiometabolic Risk
• Abdominal Obesity

Interventions

• OTHER

No Results Yet

NCT04182490 | COMPLETED | PHASE2

42 participants

LMN-101 in a Campylobacter Human Challenge Model

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2022-02-21

Completion:

2022-10-04

Conditions

• Campylobacter Infections

Interventions

• BIOLOGICAL
• DRUG

Results Available