Clinical Trials Updated in 2025

NCT05102760 | ACTIVE_NOT_RECRUITING | NA

80 participants

PENG vs. FIC Block for Hip Fracture ED Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-10-20
Completion:: 2026-06-30

Conditions

Pain
Hip Fracture

Interventions

PROCEDURE

No Results Yet

NCT05081024 | RECRUITING

50 participants

Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-09-03
Completion:: 2026-09-03

Conditions

Rectal Adenocarcinoma
Stage II Rectal Cancer AJCC v8
Stage IIA Rectal Cancer AJCC v8
Stage IIB Rectal Cancer AJCC v8
Stage IIC Rectal Cancer AJCC v8
Stage III Rectal Cancer AJCC v8
Stage IIIA Rectal Cancer AJCC v8
Stage IIIB Rectal Cancer AJCC v8
Stage IIIC Rectal Cancer AJCC v8

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05078957 | RECRUITING

132 participants

Microbiota Footprint and Frailty Phenotype in Virologically Suppressed People Living With HIV

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2023-12-05
Completion:: 2030-03-31

Conditions

HIV Infections

Interventions

OTHER

No Results Yet

NCT05063708 | COMPLETED | NA

136 participants

Neuromuscular Electrostimulation in Multiple Sclerosis People With Dysphagia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2022-01-21
Completion:: 2023-04-15

Conditions

Deglutition Disorders
Multiple Sclerosis

Interventions

DEVICE

No Results Yet

NCT05057234 | ACTIVE_NOT_RECRUITING | NA

1500 participants

PRecision Oncology Evidence Development in Cancer Treatment - Liquid

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-06-18
Completion:: 2027-06-01

Conditions

Cancer

Interventions

DIAGNOSTIC_TEST
BEHAVIORAL

No Results Yet

NCT05037331 | RECRUITING

58 participants

Osimertinib for Advanced EGFR-positive NSCLC Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-07-22
Completion:: 2026-06-30

Conditions

EGFR Positive Non-small Cell Lung Cancer
Non Small Cell Lung Cancer

No Results Yet

NCT04954183 | COMPLETED

29 participants

Development of an EEG Diagnostic for Alzheimer's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-10-01
Completion:: 2025-07-24

Conditions

Mild Cognitive Impairment
Alzheimer Disease
Dementia With Lewy Bodies
Normal Control APOE e4 Carriers and Noncarriers

No Results Yet

NCT04927832 | COMPLETED | NA

139 participants

Detection of Small Fiber Neuropathies by the Non-invasive SUDOSCAN Method During Chronic Autoimmune Pathologies and / or Unexplained Pain Syndromes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2017-07-06
Completion:: 2023-02-23

Conditions

Systemic Autoimmune Pathologies
Unexplained Pain Syndrome

Interventions

OTHER

No Results Yet

NCT04925960 | TERMINATED | PHASE3

42 participants

Oral Epalrestat Therapy in Pediatric Subjects With PMM2-CDG

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2022-11-10
Completion:: 2025-02-28

Conditions

Pmm2-CDG
Phosphomannomutase 2 Deficiency
Phosphomannomutase 2 Congenital Disorder of Glycosylation
Phosphomannomutase II Congenital Disorder of Glycosylation
Phosphomannomutase II Deficiency

Interventions

DRUG

No Results Yet

NCT04917861 | COMPLETED | PHASE2

808 participants

A Study of Zika Vaccine mRNA-1893 in Adult Participants Living in Endemic and Non-Endemic Flavivirus Areas

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-06-07
Completion:: 2024-07-26

Conditions

Zika Virus

Interventions

BIOLOGICAL

Results Available

NCT04899154 | RECRUITING | NA

80 participants

Analysis of Intestinal Microbiota as a Predictor of Response to Treatment of Spondyloarthritis With Biotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2019-07-16
Completion:: 2026-05-15

Conditions

Spondyloarthritis

Interventions

OTHER

No Results Yet

NCT04886895 | RECRUITING | NA

35 participants

Motor Training for Infants With Cerebral Palsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2022-01-07
Completion:: 2027-01-01

Conditions

Cerebral Palsy

Interventions

OTHER

No Results Yet

NCT04875702 | RECRUITING | PHASE4

650 participants

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2024-02-22
Completion:: 2028-09-01

Conditions

Gout

Interventions

DRUG

No Results Yet

NCT04859205 | COMPLETED | NA

229 participants

The SUPPORT-Pro Online Platform for Healthcare Professionals Treating Individuals Living With T1D

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-05-13
Completion:: 2022-12-20

Conditions

Educational Activities

Interventions

BEHAVIORAL

No Results Yet

NCT04850755 | COMPLETED | PHASE1

11 participants

A Phase I Dose Escalation Study of Selinexor Plus Nivolumab and Ipilimumab in Advanced/Metastatic Solid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-03-08
Completion:: 2025-03-17

Conditions

Advance Solid Malignancies
Metastatic Solid Malignancies

Interventions

DRUG

No Results Yet

NCT04826692 | COMPLETED | PHASE3

60 participants

TEsting METformin Against Cognitive Decline in HD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2022-04-11
Completion:: 2025-06-10

Conditions

Huntington Disease

Interventions

DRUG

No Results Yet

NCT04814095 | RECRUITING | NA

30 participants

PRecision Oncology Evidence Development in Cancer Treatment - Clinical: PREDiCTc

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-06-30
Completion:: 2028-05-01

Conditions

Cancer

Interventions

BEHAVIORAL
DIAGNOSTIC_TEST

No Results Yet

NCT04770935 | COMPLETED | PHASE1

6 participants

To Assess the Pharmacokinetics and Safety and Tolerability of Efanesoctocog Alfa (BIVV001)in Adults With Type 2N and 3 Von Willebrand Disease (VWD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-05-03
Completion:: 2022-12-01

Conditions

Von Willebrand's Disease (VWD)

Interventions

DRUG

No Results Yet

NCT04768686 | COMPLETED | PHASE2

20 participants

FLX475 Combined With Pembrolizumab in Patients With Advanced or Metastatic Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-05-18
Completion:: 2024-08-12

Conditions

Gastric Cancer

Interventions

DRUG

Results Available

NCT04743960 | COMPLETED | NA

20 participants

Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-10-05
Completion:: 2022-10-24

Conditions

Feeding Patterns
Sleep
Glucose Intolerance
Short Bowel Syndrome

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04710043 | COMPLETED | PHASE1

86 participants

Dose Escalation Trial of BNT152+153 in Patients With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-06-08
Completion:: 2025-09-10

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT04694248 | RECRUITING | NA

172 participants

Anticoagulant Plus Antiplatelet Therapy Following Iliac Vein Stenting

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-11-03
Completion:: 2026-12-31

Conditions

Deep Vein Thrombosis
Iliac Vein Thrombosis
Iliac Vein Obstruction
Iliac Vein Stenosis
Iliac Vein Compression Syndrome

Interventions

DRUG

No Results Yet

NCT04682145 | ENROLLING_BY_INVITATION

50 participants

Adverse Event Data Collection From the EUHASS Registry on Turoctocog Alfa Pegol

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-12-09
Completion:: 2026-02-01

Conditions

Haemophilia A

Interventions

DRUG

No Results Yet

NCT04681131 | COMPLETED | PHASE2

85 participants

CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-03-17
Completion:: 2025-07-09

Conditions

Non-Small-Cell Lung Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT04602260 | COMPLETED

211 participants

Functional Recovery of Hospitalised Patients With COVID-19: The COREG Extension Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-06-09
Completion:: 2024-01-08

Conditions

Covid19
Corona Virus Infection
Mobility Limitation
Frailty

No Results Yet

NCT04589247 | COMPLETED

104 participants

Improving Cancer On-treatment Symptom Management

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-11-16
Completion:: 2023-07-23

Conditions

Cancer
Thoracic Neoplasms
Gastrointestinal Cancer
Lung Cancer

Results Available

NCT04585711 | WITHDRAWN | PHASE1

0 participants

Pharmacokinetics and Pharmacodynamics of Biologic Drugs in Obese Patients With Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2026-07-01
Completion:: 2027-02-28

Conditions

Juvenile Idiopathic Arthritis
Rheumatoid Arthritis
Obesity

Interventions

DRUG

No Results Yet

NCT04582149 | COMPLETED | NA

30 participants

Eye-Control Trial: Wearable Eye-Tracking Device as Means of Communication

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2021-05-19
Completion:: 2023-01-23

Conditions

Acute Respiratory Failure Requiring Mechanical Ventilation

Interventions

DEVICE

Results Available

NCT04578483 | COMPLETED

634 participants

Postoperative Pain Management of Therapeutic Surgery: a Prospective, Observational Cohort Study.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-10-27
Completion:: 2022-09-30

Conditions

Postoperative Pain

Interventions

OTHER

No Results Yet

NCT04523987 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

A Pilot Study of Ciprofloxacin Plus Gemcitabine and Nab-Paclitaxel Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2019-02-22
Completion:: 2027-02-28

Conditions

Metastatic Pancreatic Ductal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT04520269 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

74 participants

A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-07-13
Completion:: 2026-07-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT04446962 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

118 participants

LOC-R01 Study of Lenalidomide and Ibrutinib in Association With Rituximab-Methotrexate Procarbazine Vincristin (R-MPV)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-10-30
Completion:: 2035-02-02

Conditions

Lymphoma, Large B-Cell, Diffuse
Central Nervous System Neoplasms, Primary

Interventions

DRUG

No Results Yet

NCT04423952 | WITHDRAWN

0 participants

Validity of the French Version of the Quality of Life Questionnaire COMQ12-FR

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-05-20
Completion:: 2020-05-20

Conditions

Chronic Otitis Media

Interventions

OTHER

No Results Yet

NCT04417465 | COMPLETED | PHASE1

101 participants

First In Human Study With ABBV-CLS-579 When Given Alone and In Combination In Participants With Locally Advanced Or Metastatic Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-06-03
Completion:: 2025-08-21

Conditions

Advanced Solid Tumors Cancer

Interventions

DRUG

No Results Yet

NCT04400539 | RECRUITING | PHASE2

20 participants

The IMmunotherapy Pleural 5-ALA PDT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2022-05-09
Completion:: 2026-05-09

Conditions

Mesotheliomas Pleural
Malignant Pleural Mesothelioma

Interventions

DEVICE
DRUG

No Results Yet

NCT04314752 | RECRUITING

4000 participants

Development of a Research Infrastructure for Understanding and Addressing Multiple Myeloma Disparities

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-09-01
Completion:: 2026-05-30

Conditions

Multiple Myeloma

No Results Yet

NCT04233138 | COMPLETED | NA

285 participants

SUPPORT Online Training Platform for Type 1 Diabetes Self-management Education and Support (SUPPORT)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-02-05
Completion:: 2023-03-19

Conditions

Type 1 Diabetes Mellitus With Hypoglycemia

Interventions

OTHER

No Results Yet

NCT04190706 | COMPLETED | NA

62 participants

Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk Prevention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2020-01-21
Completion:: 2022-05-17

Conditions

Cardiometabolic Risk
Abdominal Obesity

Interventions

OTHER

No Results Yet

NCT04182490 | COMPLETED | PHASE2

42 participants

LMN-101 in a Campylobacter Human Challenge Model

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-25
Start Date:: 2022-02-21
Completion:: 2022-10-04

Conditions

Campylobacter Infections

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04132206 | RECRUITING

60 participants

Longitudinal Characterization of Microbial Signature in Systemic Sclerosis Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-25
Start Date:: 2019-10-08
Completion:: 2026-06-03

Conditions

Systemic Sclerosis

Interventions

OTHER

No Results Yet