Clinical Trials Updated in 2025

NCT05468164 | COMPLETED | PHASE1

20 participants

A Study of Effect of Food and a Proton Pump Inhibitor on Selpercatinib (LY3527723) in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2018-05-31
Completion:: 2018-09-13

Conditions

Healthy

Interventions

DRUG

Results Available

NCT05464524 | COMPLETED

179 participants

Environmental Factors on DFUs Incidence - a Mixed-mode Survey

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-19
Start Date:: 2023-10-19
Completion:: 2025-02-15

Conditions

Diabetic Foot
Diabetic Foot Ulcer

Interventions

OTHER

No Results Yet

NCT05445609 | SUSPENDED | PHASE2

10 participants

Vidutolimod (CMP-001) in Combination With Nivolumab for the Treatment of Metastatic Castration Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2023-06-07
Completion:: 2027-06-23

Conditions

Metastatic Prostate Adenocarcinoma
Stage IV Prostate Cancer AJCC v8

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05411016 | ACTIVE_NOT_RECRUITING | PHASE1

157 participants

A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-08-03
Completion:: 2024-12-10

Conditions

Healthy Volunteers
Systemic Lupus Erythematosus (SLE)
Cutaneous Lupus Erythematosus (CLE)

Interventions

DRUG

No Results Yet

NCT05404737 | COMPLETED | NA

90 participants

Interchangeability of Right Ventricle Longitudinal Shortening in Echocardiography

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-05-31
Completion:: 2023-01-01

Conditions

Right Ventricle
Speckle Tracking
Strains
Cardiac Surgery

Interventions

OTHER

No Results Yet

NCT05391841 | WITHDRAWN

0 participants

Non-interventional Study in Pediatric Patients Treated With NOVOCART Inject in the Knee

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-19
Start Date:: 2025-05-31
Completion:: 2029-05-31

Conditions

Cartilage Disease

Interventions

DRUG

No Results Yet

NCT05372393 | RECRUITING | NA

118 participants

Carpal Tunnel Release Under Local Anaesthesia With or Without Distal Median Nerve Block

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-09-21
Completion:: 2025-12-31

Conditions

Carpal Tunnel Syndrome

Interventions

PROCEDURE

No Results Yet

NCT05365295 | COMPLETED | NA

28 participants

Study of ADHD Children's Sensitivity to Memory Error Production

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-06-28
Completion:: 2022-10-17

Conditions

ADHD

Interventions

OTHER

No Results Yet

NCT05354440 | ACTIVE_NOT_RECRUITING

80 participants

Post Marketing Clinical Follow Up of the BioProtect Balloon Implant System

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-01-01
Completion:: 2026-01-31

Conditions

Prostate Cancer

No Results Yet

NCT05338489 | COMPLETED | PHASE1

24 participants

A Study of Effects of Itraconazole and Rifampin on Selpercatinib (LY3527723) in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2018-05-11
Completion:: 2018-07-28

Conditions

Healthy

Interventions

DRUG

Results Available

NCT05301192 | RECRUITING | EARLY_PHASE1

26 participants

Angiotensin-(1-7) Cardiovascular Effects in Aging

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-12-09
Completion:: 2026-12-31

Conditions

Aging

Interventions

DRUG

No Results Yet

NCT05282394 | ACTIVE_NOT_RECRUITING | NA

30 participants

Newborn Abdominal Massage to Prevent Hyperbilirubinemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-08-01
Completion:: 2026-06-30

Conditions

Newborn Jaundice

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05267236 | COMPLETED | NA

820 participants

TYRO Couples Project Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2023-04-11
Completion:: 2024-11-30

Conditions

Couples

Interventions

OTHER

Results Available

NCT05188183 | RECRUITING | NA

290 participants

Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-09-01
Completion:: 2027-06-30

Conditions

Phantom Limb Pain

Interventions

DEVICE
BEHAVIORAL
OTHER

No Results Yet

NCT05186389 | COMPLETED

30 participants

Jejunal Luminal and Colonic Mucosa-Associated Microbiota in Metabolic Diseases: Methods, Identification and Causalities

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-01-17
Completion:: 2024-01-17

Conditions

Diabetes Mellitus
Obesity
Metabolic Disease

No Results Yet

NCT05169775 | COMPLETED

16 participants

A Single Centre, Prospective, Observational Study to Assess the Use of the Rehabilitation Tool, GripAble, in Patients With Upper Limb Spasticity Receiving Botulinum Toxin-A (BoNT-A) in the United Kingdom (UK).

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-03-02
Completion:: 2023-01-04

Conditions

Upper Limb Spasticity (ULS)

No Results Yet

NCT05142722 | COMPLETED | PHASE3

2530 participants

Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-12-15
Completion:: 2024-09-26

Conditions

Dyslipidemias
High Cholesterol
Hypercholesterolemia
Familial Hypercholesterolemia
Atherosclerotic Cardiovascular Disease

Interventions

DRUG

Results Available

NCT05114889 | COMPLETED | PHASE1

54 participants

Safety and Tolerability of BSI-045B in Healthy Adult Subjects and Patients With Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-10-25
Completion:: 2023-02-15

Conditions

Atopic Dermatitis

Interventions

BIOLOGICAL

No Results Yet

NCT05112705 | RECRUITING | NA

1800 participants

Diagnosing Deep-vein Thrombosis Early in Critically Ill Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2023-03-21
Completion:: 2026-03-31

Conditions

Deep Vein Thrombosis
Pulmonary Embolism

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05103618 | WITHDRAWN | PHASE2

0 participants

Effect of Meditation and Controls and Subjects With Parkinson's Disease on Brain Activity Measured by fMRI With FDOPA

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-07-08
Completion:: 2025-07-21

Conditions

Parkinson Disease
Idiopathic Parkinson Disease

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT05095818 | COMPLETED | NA

440 participants

Impact of Nursing Involvement on Implementation of HIV Prevention Services

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-04-01
Completion:: 2021-11-17

Conditions

Pre-Exposure Prophylaxis (PrEP)

Interventions

OTHER

No Results Yet

NCT05094297 | RECRUITING | NA

25 participants

Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-10-01
Completion:: 2026-12-31

Conditions

Chronic Pain
Acute Pain
Fatigue
Depression

Interventions

BEHAVIORAL

No Results Yet

NCT05079035 | COMPLETED | PHASE2

90 participants

Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-12-06
Completion:: 2025-03-07

Conditions

Knee Osteoarthritis
Knee Pain Chronic
Knee Arthritis

Interventions

BIOLOGICAL

No Results Yet

NCT05053191 | ACTIVE_NOT_RECRUITING | NA

84 participants

Advancing Nursing Practices in Hospital Oncology Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-09-03
Completion:: 2026-09-03

Conditions

Gastrointestinal Cancer
Gastrointestinal Disease
Nurse's Role

Interventions

BEHAVIORAL

No Results Yet

NCT05004051 | RECRUITING

200 participants

ViTAA Registry Pre- and Post-Operative Monitoring for Endovascular Aortic Aneurysm Repair and Serial Monitoring for AAA

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-12-15
Completion:: 2026-12-31

Conditions

Abdominal Aortic Aneurysms

Interventions

DEVICE

No Results Yet

NCT05000788 | ACTIVE_NOT_RECRUITING | NA

60 participants

Neurophysiological RCT of Qigong in Elderly With Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-08-09
Completion:: 2026-03-31

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT04982497 | COMPLETED | NA

548 participants

Development and Evaluation of a Psychological Intervention in Videogame Format for the Promotion of Active Aging

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-09-21
Completion:: 2024-05-31

Conditions

Aging
Aging Problems

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT04979793 | SUSPENDED | PHASE1

338 participants

Role of L-citrulline in Prevention of Pregnancy Associated Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-07-28
Completion:: 2027-07-30

Conditions

Pregnancy Induced Hypertension
Preeclampsia and Eclampsia
Gestational Hypertension

Interventions

DRUG

No Results Yet

NCT04971980 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

9 participants

Safety and Efficacy Study of Human Umbilical Cord-Derived Mesenchymal Stem Cells(BC-U001) for Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-04-12
Completion:: 2023-07-10

Conditions

Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT04948580 | COMPLETED | NA

3264 participants

Preventing Violence by Teachers Against Children in Sub-Saharan Africa

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-09-20
Completion:: 2024-12-31

Conditions

Violence by Teachers

Interventions

BEHAVIORAL

No Results Yet

NCT04886219 | COMPLETED

70 participants

Studies of the Angle Kappa and the Angle Alpha

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-05-19
Completion:: 2021-10-04

Conditions

No Eye Disorder

Interventions

OTHER

No Results Yet

NCT04876157 | RECRUITING | NA

300 participants

Artificial Intelligence-aimed Point-of-care Ultrasound Image Interpretation System

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2020-08-01
Completion:: 2026-12-31

Conditions

Ultrasound Image Interpretation

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04874454 | RECRUITING | NA

200 participants

Evaluating Potential Risk of Choking by Laryngeal Ultrasound in Patients With Acute Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2023-07-14
Completion:: 2026-12-31

Conditions

Acute Stroke

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04874012 | RECRUITING | PHASE2

94 participants

Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-06-12
Completion:: 2025-10-31

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG
OTHER

No Results Yet

NCT04827030 | COMPLETED | PHASE4

292 participants

ER-One: A Double-blind Trial of Erector Spinae Block (ESP) Versus Paravertebral Block (PVB) Before Breast Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-06-28
Completion:: 2023-06-14

Conditions

Breast Surgery

Interventions

DRUG

No Results Yet

NCT04821635 | WITHDRAWN | NA

0 participants

Effects of FES-Rowing in Neurological Disorders (FES-ROW)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2024-04-30
Completion:: 2026-12-31

Conditions

Spinal Cord Injuries

Interventions

DEVICE

No Results Yet

NCT04817592 | NOT_YET_RECRUITING

100 participants

Characterization of the Corneal Biomechanics of Patients Treated by Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) to Correct Myopia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-19
Start Date:: 2026-06-01
Completion:: 2027-06-01

Conditions

Myopia

Interventions

PROCEDURE

No Results Yet

NCT04792203 | ACTIVE_NOT_RECRUITING

100 participants

The Evaluation of the Ultrasound-guided Clinical Procedure Simulation Curriculum

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-19
Start Date:: 2021-09-18
Completion:: 2026-12-31

Conditions

Ultrasound Performance

No Results Yet

NCT04763915 | ACTIVE_NOT_RECRUITING | NA

720 participants

Improving Care After Inherited Cancer Testing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2022-08-05
Completion:: 2027-12-31

Conditions

Inherited Cancer Syndrome
Prostate Cancer
Colorectal Cancer
Endometrial Cancer
Breast Cancer

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT04721769 | TERMINATED | NA

6 participants

Endoscopic Strip Craniectomy for Treatment of Sagittal Craniosynostosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-19
Start Date:: 2020-12-18
Completion:: 2025-05-01

Conditions

Craniosynostosis, Sagittal

Interventions

PROCEDURE

No Results Yet