Clinical Trials

NCT03787758 | COMPLETED | PHASE1

6 participants

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of SAGE-718 Oral Solution in Patients With Huntington's Disease - Part B

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2019-02-28

Completion:

2019-10-07

Conditions

• Huntington Disease

Interventions

• DRUG

No Results Yet

NCT03771586 | COMPLETED | PHASE1

22 participants

A Study to Assess the Electrophysiology, Safety, Tolerability, and Pharmacokinetics of SAGE-718 Using a Ketamine Challenge in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2018-09-24

Completion:

2018-12-17

Conditions

• Healthy Volunteer

Interventions

• DRUG

No Results Yet

NCT03770780 | COMPLETED | PHASE1

19 participants

A Study to Assess the Electrophysiology, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response Using Magnetic Resonance Imaging of SAGE-718 Using a Ketamine Challenge in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2018-11-12

Completion:

2019-03-08

Conditions

• Healthy Volunteer

Interventions

• DRUG

No Results Yet

NCT03692897 | TERMINATED

1708 participants

An Observational Study of Patients With Chronic Hepatitis B (CHB) Infection

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2018-10-11

Completion:

2025-09-10

Conditions

• Hepatitis B
• Hepatitis
• Liver Diseases

Interventions

• OTHER

No Results Yet

NCT03564626 | COMPLETED | NA

232 participants

Health IT Generated PROs to Improve Outcomes in Cirrhosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2018-06-22

Completion:

2024-04-22

Conditions

• Cirrhosis

Interventions

• OTHER

Results Available

NCT03545906 | COMPLETED | NA

326 participants

Telemedicine Enhanced Asthma Management - Uniting Providers

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2018-11-09

Completion:

2024-05-06

Conditions

• Asthma in Children

Interventions

• OTHER

Results Available

NCT03532191 | COMPLETED | NA

10 participants

Improving the HIV PrEP Cascade Using an Intervention for Healthcare Providers

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2018-11-01

Completion:

2020-09-30

Conditions

• HIV/AIDS

Interventions

• OTHER

No Results Yet

NCT03512418 | COMPLETED | PHASE3

30 participants

Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2019-06-20

Completion:

2024-04-10

Conditions

• HIV Infections
• Substance Use Disorders

Interventions

• BEHAVIORAL
• DEVICE
• DRUG

Results Available

NCT03508310 | COMPLETED | NA

4003 participants

A Waiting Room-Delivered Video to Enhance Clinical Outcomes Among Persons Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2016-06-01

Completion:

2017-03-30

Conditions

• HIV Infections

Interventions

• OTHER

No Results Yet

NCT03467958 | TERMINATED | PHASE3

854 participants

An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2018-08-24

Completion:

2024-10-31

Conditions

• Crohn Disease

Interventions

• DRUG

Results Available

NCT03406897 | COMPLETED | PHASE1/PHASE2

27 participants

Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2018-07-23

Completion:

2024-07-31

Conditions

• Diabetes Mellitus, Type 1
• Hypoglycemia
• Diabetes Mellitus
• Diabetes, Autoimmune

Interventions

• DRUG

Results Available

NCT03403686 | RECRUITING

104 participants

Liver X Receptor (LXR) as a Novel Therapeutic Target in Diabetic Retinopathy (DR)

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2018-01-11

Completion:

2026-12-31

Conditions

• Diabetic Retinopathy

Interventions

• BIOLOGICAL

No Results Yet

NCT03266016 | COMPLETED | NA

248 participants

Real-time Effort Driven VENTilator Management

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2017-10-21

Completion:

2024-04-01

Conditions

• Ventilation Therapy; Complications
• Diaphragm Disease
• Pediatric Respiratory Diseases

Interventions

• OTHER
• DIAGNOSTIC_TEST

Results Available

NCT03146546 | ENROLLING_BY_INVITATION

200 participants

STUDY00015328: Sepsis Endotypes

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2020-08-06

Completion:

2026-06-30

Conditions

• Sepsis

No Results Yet

NCT03142321 | COMPLETED | PHASE4

48 participants

Defining Predictors of RT Response to Vedolizumab in IBD

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2018-06-08

Completion:

2024-05-22

Conditions

• Crohn Disease of Small Intestine

Interventions

• DRUG

Results Available

NCT03087955 | COMPLETED | PHASE2/PHASE3

208 participants

Efficacy and Safety of Acoziborole (SCYX-7158) in Patients With Human African Trypanosomiasis Due to T.b. Gambiense

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2016-10-11

Completion:

2020-09-08

Conditions

• Trypanosomiasis, African
• Gambiense Trypanosomiasis
• Sleeping Sickness

Interventions

• DRUG

Results Available

NCT03083886 | COMPLETED | NA

3087 participants

Spine Pain INtervention to Enhance Care Quality And Reduce Expenditure

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2017-06-05

Completion:

2021-03-31

Conditions

• Back Pain
• Neck Pain

Interventions

• OTHER

Results Available

NCT03032601 | ENROLLING_BY_INVITATION | NA

55 participants

Physiological Effects of N-Acetyl Cysteine in Patients With Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2017-01-05

Completion:

2027-07-08

Conditions

• Multiple Sclerosis

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT02925156 | COMPLETED

2506 participants

Modeling the Epidemiologic Transition Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2008-07-16

Completion:

2024-05-20

Conditions

• Obesity
• Diabetes

Results Available

NCT02869282 | WITHDRAWN

0 participants

Circulating And Intra-Tumoral Chemokines In Patients With Prostate Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2011-06-30

Completion:

2016-12-31

Conditions

• Prostate Cancer

Interventions

• OTHER

No Results Yet

NCT02833285 | RECRUITING

60 participants

B Cell Functions in Periodontitis

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2015-05-01

Completion:

2025-09-30

Conditions

• Chronic Periodontitis
• Aggressive Periodontitis

No Results Yet

NCT02170181 | COMPLETED

149 participants

Clinical Registry for Oligometastic Disease, Consolidation Therapy, Debulking Prior to Chemotherapy, or Re-Irradiation

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2014-05-28

Completion:

2025-08-31

Conditions

• Cancer Patients Receiving Stereotactic Body RTX

Interventions

• RADIATION

No Results Yet

NCT02129751 | NOT_YET_RECRUITING | PHASE4

246 participants

Efficacy and Safety of Bupropion Hydrobromide in Adolescents and Children With Major Depressive Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2026-06-30

Completion:

2029-07-31

Conditions

• Major Depressive Disorder

Interventions

• DRUG

No Results Yet

NCT02129660 | COMPLETED | PHASE2

105 participants

Comparator Study of the Effect of Glycopyrrolate and Glycopyrronium in Subjects With Axillary Hyperhidrosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2014-04-30

Completion:

2015-01-31

Conditions

• Hyperhidrosis

Interventions

• DRUG
• OTHER

Results Available

NCT02040298 | COMPLETED | PHASE2

50 participants

Assessment of Clemastine Fumarate as a Remyelinating Agent in Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2014-01-31

Completion:

2015-09-30

Conditions

• Multiple Sclerosis, Relapsing-Remitting

Interventions

• DRUG

Results Available

NCT01311258 | RECRUITING

400 participants

Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2007-08-31

Completion:

2030-08-31

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndrome

No Results Yet

NCT01241708 | COMPLETED | PHASE3

148 participants

Tandem Auto Stem Cell Transplant With Melphalan Followed by Melphalan and Bortezomib in Patients With Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2010-04-08

Completion:

2023-07-15

Conditions

• Multiple Myeloma
• Auto Stem Cell Transplant

Interventions

• DRUG

Results Available

NCT01061515 | ACTIVE_NOT_RECRUITING | PHASE1

21 participants

Biweekly Intraperitoneal Oxaliplatin With Systemic Capecitabine and Bevacizumab for Patients With Peritoneal Carcinomatosis From Appendiceal or Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-17

Start Date:

2011-05-10

Completion:

2026-09-27

Conditions

• Carcinoma

Interventions

• DRUG

No Results Yet

NCT00608764 | ACTIVE_NOT_RECRUITING

10718 participants

Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2007-11-30

Completion:

2028-08-31

Conditions

• Pulmonary Disease, Chronic Obstructive
• Emphysema
• Bronchitis, Chronic

No Results Yet

NCT00267501 | RECRUITING

5000 participants

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-17

Start Date:

2005-05-31

Completion:

2050-01-31

Conditions

• Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease
• Food Allergy

No Results Yet

NCT07177300 | RECRUITING | PHASE4

50 participants

Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2024-12-19

Completion:

2026-12-31

Conditions

• Sickle Cell Anemia (HbSS)
• Sickle-β0-thalassemia (HbSβ0)

Interventions

• DRUG

No Results Yet

NCT07177274 | ACTIVE_NOT_RECRUITING | NA

20 participants

Evaluation of Skin Stiffness Changes in Wounds Before and After Low-Level Laser Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2024-09-19

Completion:

2025-07-24

Conditions

• Wound - in Medical Care

Interventions

• RADIATION

No Results Yet

NCT07177248 | COMPLETED | NA

136 participants

12-Week Family-Based Multicomponent Program to Improve 24-Hour Movement Behaviors in Parents and Children

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-05-01

Completion:

2023-10-31

Conditions

• Physical Activity
• Sedentary Behaviors
• Exercise
• Sleep
• Physical Fitness
• Health Promotion

Interventions

• BEHAVIORAL

No Results Yet

NCT07177235 | NOT_YET_RECRUITING | PHASE4

50 participants

Ketamine for the Treatment of Refractory Status Epilepticus

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2025-11-30

Completion:

2027-07-31

Conditions

• Refractory Status Epilepticus

Interventions

• DRUG

No Results Yet

NCT07177222 | COMPLETED

38 participants

Compare the Quality of Life of Patients With Achalasia Cardia (AC) After Laparoscopic and Open Esophagocardiomyotomy.

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2017-12-01

Completion:

2025-07-30

Conditions

• Achalasia Cardia
• GERD-HRQL Scale
• Eckardt Scale

Interventions

• PROCEDURE

No Results Yet

NCT07177196 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

1 participants

Personalized Antisense Oligonucleotide Therapy for a Single Participant With PRPH2 Mutation Associated With Retinal Dystrophy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2025-08-28

Completion:

2027-08-31

Conditions

• Retinal Dystrophy

Interventions

• DRUG

No Results Yet

NCT07177170 | RECRUITING | NA

1422 participants

Impact of a Single Versus Multiple Visits on the Cervical Cancer Screening Completeness, Feasibility and Acceptability Among Women Living With HIV in Cameroon

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2024-12-12

Completion:

2026-04-30

Conditions

• Cervical Cancer Screening
• HIV

Interventions

• OTHER

No Results Yet

NCT07177157 | NOT_YET_RECRUITING | PHASE1

150 participants

The Prospective Improved Vitamin D Study for Inflammatory Bowel Disease Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2025-10-31

Completion:

2027-03-31

Conditions

• Ulcerative Colitis (UC)
• IBD (Inflammatory Bowel Disease)
• Crohn Disease (CD)

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT07177118 | NOT_YET_RECRUITING | PHASE3

260 participants

Risankizumab for Fibrostenotic Crohn's Disease Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2025-10-20

Completion:

2028-06-20

Conditions

• Crohn Disease
• Crohn Disease and Ulcerative Colitis

Interventions

• DRUG

No Results Yet

NCT07177105 | NOT_YET_RECRUITING | PHASE2

118 participants

Primary Tumor Resection With Sintilimab and Chemotherapy in Advanced NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2025-09-10

Completion:

2028-10-01

Conditions

• Non Small Cell Lung Cancer

Interventions

• PROCEDURE
• DRUG

No Results Yet