Clinical Trials Updated in 2025

NCT06016348 | COMPLETED

400 participants

PROMISE: PRedictors Of Good outcoMes in Thrombectomy for Large Infarct Core Stroke Evaluation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-07-28
Completion:: 2025-08-01

Conditions

Acute Ischemic Stroke

Interventions

PROCEDURE

No Results Yet

NCT06000488 | WITHDRAWN | NA

0 participants

Trial to Evaluate the Efficacy of a Manualized Reflective Writing Program for Clinical Phase Physician Assistant (PA) Students.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2025-01-31
Completion:: 2026-01-31

Conditions

Burn Out
Student Burnout
Physician Assistant Student Burnout

Interventions

BEHAVIORAL

No Results Yet

NCT05950503 | RECRUITING

100 participants

Role of MRI in the Evaluation of Hepatic Metastases of Colorectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-07-10
Completion:: 2026-06-07

Conditions

Colorectal Cancer

Interventions

RADIATION

No Results Yet

NCT05926414 | ACTIVE_NOT_RECRUITING

15000 participants

To Evaluate the Efficacy and Safety of Envlo Tablet or Envlomet SR Tablet in Patients With Type II Diabetes Mellitus

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-09-21
Completion:: 2025-01-17

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT05900206 | RECRUITING | PHASE2

370 participants

Trastuzumab Deruxtecan Versus Standard Neoadjuvant Treatment for HER2-positive Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-10-26
Completion:: 2027-04-30

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05899062 | COMPLETED | NA

32 participants

Telerehabilitation-based Exercise Training in Constipated Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-06-01
Completion:: 2024-05-27

Conditions

Constipation

Interventions

OTHER

No Results Yet

NCT05897398 | COMPLETED

1100 participants

SEMASEARCH, Retrospective/Prospective Cohort Nested at ATUc/AP2 WEGOVY®

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-02
Start Date:: 2024-06-10
Completion:: 2025-06-10

Conditions

Obesity
Bariatric Surgery
Binge Eating Disorder
Syndromic Obesity
Sarcopenic Obesity
Iatrogenic Obesity
Psychotropic Drugs

Interventions

OTHER

No Results Yet

NCT05853302 | COMPLETED

316 participants

Robot-assisted vs Laparoscopic Lateral Transabdominal Adrenalectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-12-15
Completion:: 2024-06-01

Conditions

Adrenalectomy; Status

No Results Yet

NCT05834296 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

30 participants

Study in Subjects With Mild-to-Moderate Alzheimer's Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-07-05
Completion:: 2028-03-03

Conditions

Alzheimer Disease

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05828095 | COMPLETED | PHASE1

20 participants

A Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding a Native-like HIV Env Trimer and Interleukin-12 (INO-6160), Alone or in a Prime-boost Regimen With 3M-052-AF + Alum Adjuvanted VRC HIV Env Trimer 4571 in Adult Participants Without HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-04-05
Completion:: 2025-01-23

Conditions

HIV-1-infection

Interventions

BIOLOGICAL

Results Available

NCT05826782 | COMPLETED | NA

30 participants

Effect of Antioxidant Food Supplement on Sperm Proteomic Structure and Semen Parameters

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-11-30
Completion:: 2024-08-30

Conditions

Asthenozoospermia

Interventions

BIOLOGICAL

No Results Yet

NCT05815576 | COMPLETED | NA

72 participants

Biomechanics and Intrinsic Foot Muscle Roles in Subjects With Chronic Ankle Instability

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-02-03
Completion:: 2025-02-17

Conditions

Chronic Ankle Instability
Lateral Ankle Sprain

Interventions

BEHAVIORAL

No Results Yet

NCT05815524 | TERMINATED | NA

30 participants

Physical Activity in Patients With Parkinson's Disease: a "Disease Modifying" Intervention?

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-05-02
Completion:: 2024-12-31

Conditions

Parkinson Disease

Interventions

OTHER

No Results Yet

NCT05790174 | ACTIVE_NOT_RECRUITING

700 participants

Weight-loss Treatment Program in Children and Adolescents

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-02
Start Date:: 2010-01-01
Completion:: 2022-12-30

Conditions

Childhood Obesity
Health Behavior
Weight Loss
Motivation

Interventions

BEHAVIORAL

No Results Yet

NCT05785429 | COMPLETED | NA

59 participants

The Effect of Colchicine on Food-related Effort-based Decision Making in Brain and Behaviour in Overweight and Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-08-02
Completion:: 2025-01-20

Conditions

Overweight and Obesity

Interventions

DRUG

No Results Yet

NCT05754996 | COMPLETED | PHASE3

80 participants

Efficacy and Safety of Nifuroxazide in the Treatment of Hepatic Encephalopathy in Egyptian Patients With Liver Cirrhosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-03-12
Completion:: 2025-07-29

Conditions

Hepatic Encephalopathy

Interventions

DRUG

No Results Yet

NCT05749770 | COMPLETED

220 participants

Hormonal Contributors to COVID-19 Infection (COV-ENDO)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-02
Start Date:: 2020-05-01
Completion:: 2023-12-31

Conditions

COVID-19 Pandemic
Endocrine System Diseases

Interventions

OTHER

No Results Yet

NCT05742906 | RECRUITING | NA

92 participants

CorMatrix Cor TRICUSPID ECM Valve Replacement - Pivotal Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-08-10
Completion:: 2025-12-31

Conditions

Tricuspid Valve Disease
Tricuspid Valve Insufficiency

Interventions

DEVICE

No Results Yet

NCT05731986 | RECRUITING | NA

12 participants

Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-12-01
Completion:: 2026-08-31

Conditions

Spinal Cord Injuries
Spinal Cord Diseases
Trauma, Nervous System
Nervous System Diseases
Central Nervous System Diseases
Hypotension
Orthostatic Hypotension
Cardiovascular Diseases
Acute Spinal Cord Injury
Blood Pressure

Interventions

DIAGNOSTIC_TEST
DEVICE

No Results Yet

NCT05725499 | RECRUITING | NA

5 participants

The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-02-01
Completion:: 2026-08-01

Conditions

Spinal Cord Injuries
Hypotension
Orthostatic Hypotension
Spinal Cord Diseases
Cardiovascular Diseases
Trauma, Nervous System
Central Nervous System Diseases
Nervous System Diseases
Blood Pressure

Interventions

DEVICE
DIAGNOSTIC_TEST

No Results Yet

NCT05706779 | RECRUITING | PHASE2

30 participants

Encorafenib Plus Cetuximab in a Neoadjuvant Setting in Patients With BRAF Mutation Localised Colon or Upper Rectum Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-02-13
Completion:: 2026-12-30

Conditions

Colorectal Cancer
BRAF V600E Mutation Positive

Interventions

DRUG

No Results Yet

NCT05698810 | RECRUITING | NA

150 participants

Preparation and Feasibility of Exams for Expected Studies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-03-20
Completion:: 2033-03-20

Conditions

Healthy Volunteers
Parkinson's Disease Patients
Para/Tetraplegic Patients

Interventions

OTHER

No Results Yet

NCT05694052 | COMPLETED | NA

56 participants

Impact of a Multifaceted Intervention of Environment Control in the ICU to Optimize Quantity and Quality of Sleep

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-05-02
Completion:: 2025-01-31

Conditions

Sleep Disturbance

Interventions

BEHAVIORAL

No Results Yet

NCT05669482 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

40 participants

Study of Avutometinib (VS-6766) +Defactinib With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-03-22
Completion:: 2026-08-31

Conditions

KRAS Activating Mutation
Metastatic Cancer
Pancreas Cancer
Neoplasms Pancreatic
Malignant Neoplasm of Pancreas

Interventions

DRUG

No Results Yet

NCT05669365 | COMPLETED | NA

1227 participants

The Care Ecosystem Consortium Effectiveness Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-01-17
Completion:: 2025-08-15

Conditions

Dementia
Dementia, Vascular
Dementia With Lewy Bodies
Dementia Alzheimers
Frontotemporal Dementia

Interventions

BEHAVIORAL

No Results Yet

NCT05642039 | COMPLETED | NA

37 participants

Mindfulness Training Hidradenitis Suppurativa (HS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2023-05-01
Completion:: 2025-08-21

Conditions

Hidradenitis Suppurativa
Quality of Life

Interventions

BEHAVIORAL

No Results Yet

NCT05619523 | COMPLETED | NA

885 participants

Developing Inclusive Youth: Promoting Intergroup Friendships and Inclusive Classrooms in Childhood

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-09-27
Completion:: 2023-12-23

Conditions

Social Exclusion
Prejudice, Racial
Prejudice
Sexism
Peer Group

Interventions

BEHAVIORAL

Results Available

NCT05597436 | NO_LONGER_AVAILABLE

Intermediate-Sized Expanded Access Study

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-02

Conditions

Amyotrophic Lateral Sclerosis

Interventions

DRUG

No Results Yet

NCT05585320 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

209 participants

A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-10-31
Completion:: 2026-06-30

Conditions

Advanced Solid Tumor
Pancreatic Adenocarcinoma
Malignant Melanoma (Cutaneous)
Non-small Cell Lung Cancer (NSCLC)

Interventions

DRUG

No Results Yet

NCT05530850 | COMPLETED | NA

62 participants

The Effect of Holistic Corrective Exercise Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-02-15
Completion:: 2022-05-15

Conditions

Kyphosis Thoracic

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05511688 | ACTIVE_NOT_RECRUITING

637 participants

National Cohort of Colorectal Cancers With Microsatellite Instability

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-02
Start Date:: 2017-03-22
Completion:: 2025-12-31

Conditions

Colorectal Cancer
Microsatellite Instability

No Results Yet

NCT05449366 | COMPLETED | PHASE1/PHASE2

7 participants

Intraperitoneal Paclitaxel for Patients With Primary Malignant Peritoneal Mesothelioma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-02-01
Completion:: 2025-06-01

Conditions

Peritoneal Malignant Mesothelioma

Interventions

DRUG

No Results Yet

NCT05417737 | RECRUITING

105 participants

Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-06-15
Completion:: 2025-12-31

Conditions

Radiation Toxicity
Chemotherapeutic Toxicity
Chemotherapy-induced Peripheral Neuropathy
Delayed Wound Healing
Chronic Pain
Refractory Pain

Interventions

OTHER

No Results Yet

NCT05393401 | RECRUITING | NA

27 participants

Photoplethysmographic Measurements of Pulse Wave Velocity (PWV) and Blood Pressure (BP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-10-25
Completion:: 2026-06-30

Conditions

Healthy Volunteers

Interventions

DEVICE

No Results Yet

NCT05335278 | TERMINATED | NA

11 participants

Tolerability and Safety of Nintedanib in Myositis Associated Interstitial Lung Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2021-06-01
Completion:: 2024-12-31

Conditions

Interstitial Lung Disease
Myopathy, Inflammatory

Interventions

DRUG

No Results Yet

NCT05331248 | COMPLETED | NA

8754 participants

Training Local Leaders to Prevent and Reduce Domestic Violence Evidence From Peru

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-05-02
Completion:: 2025-04-20

Conditions

Domestic Violence

Interventions

BEHAVIORAL

No Results Yet

NCT05323656 | COMPLETED | PHASE2

55 participants

A Study of Setanaxib Co-Administered With Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-04-06
Completion:: 2024-02-18

Conditions

Squamous Cell Carcinoma of Head and Neck

Interventions

DRUG
BIOLOGICAL

Results Available

NCT05323006 | COMPLETED | NA

40 participants

Scapular Stabilization Exercises on the Clavicular Movement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2017-06-20
Completion:: 2017-07-11

Conditions

Clavicle

Interventions

OTHER

No Results Yet

NCT05318417 | RECRUITING | NA

60 participants

Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-08-19
Completion:: 2027-05-31

Conditions

Hearing Loss, Unilateral
Deafness, Unilateral

Interventions

DEVICE

No Results Yet

NCT05314075 | COMPLETED | NA

124 participants

Determination of Core Body Temperature in Parturient Warmed With Upper or Underbody Forced Air Cover (Bair Hugger)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-02
Start Date:: 2022-12-27
Completion:: 2025-07-30

Conditions

Cesarean Section

Interventions

PROCEDURE

No Results Yet