Clinical Trials Updated in 2024

NCT04827875 | COMPLETED | PHASE1

25 participants

Safety and Efficacy of AIV001 on Scar Formation and Keloid Recurrence Following Keloidectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-06-23
Completion:: 2022-12-15

Conditions

Keloid
Scar
Incision
Excision Margin

Interventions

DRUG

No Results Yet

NCT04823689 | COMPLETED | NA

120 participants

Reduction of Anterior Glenohumeral Dislocation in Ventral Decubitus Versus Dorsal Decubitus Under Procedural Sedation

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-07-21
Completion:: 2024-02-10

Conditions

Reduction
Emergencies
Anterior Shoulder Dislocation

Interventions

PROCEDURE

No Results Yet

NCT04807777 | TERMINATED | PHASE2

3 participants

Study of Ruxolitinib in Solid Organ Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2022-04-07
Completion:: 2023-04-04

Conditions

Advanced Cutaneous Squamous Cell Carcinoma

Interventions

DRUG

Results Available

NCT04802967 | COMPLETED | PHASE1

141 participants

A Study on Ketoprofen Lysine Salt (KLS) + Gabapentin (GABA) vs KLS to Investigate Their Pharmacodynamic in Healthy Males

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-02-08
Completion:: 2022-03-30

Conditions

No Condition

Interventions

DRUG
OTHER

Results Available

NCT04795245 | COMPLETED

805 participants

Non-interventional Study for Real-world Data of Afatinib Treatment in First-line Setting and of Subsequent Therapies for Patients With Advanced Epidermal Growth Factor Receptor (EGFR) Mutation-positive Lung Adenocarcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-08-26
Completion:: 2023-10-16

Conditions

Non-squamous, Non-Small Cell Lung Cancer

Interventions

DRUG

Results Available

NCT04758533 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

13 participants

Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-04-19
Completion:: 2026-04-30

Conditions

Diffuse Intrinsic Pontine Glioma
Medulloblastoma, Childhood, Recurrent

Interventions

BIOLOGICAL

No Results Yet

NCT04749615 | COMPLETED | PHASE4

94 participants

Does PAI Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving ACB & IPACK?

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-12-17
Completion:: 2022-04-01

Conditions

Total Knee Athroplasty

Interventions

DRUG

Results Available

NCT04743973 | COMPLETED | NA

40 participants

A Study to Asses Wellness Using a Brain Sensing Device on Physicians

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-08-15
Completion:: 2024-08-01

Conditions

Stress, Emotional
Sleep
Quality of Life

Interventions

DEVICE

Results Available

NCT04741542 | TERMINATED | PHASE1

2 participants

Safety of SP-420 in the Treatment of Transfusional Iron Overload

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-03-09
Completion:: 2024-01-10

Conditions

Iron Overload

Interventions

DRUG

No Results Yet

NCT04731467 | COMPLETED | PHASE1/PHASE2

79 participants

A Study of CM24 in Combination with Nivolumab in Adults with Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-03-19
Completion:: 2024-09-30

Conditions

Solid Tumor
Non Small Cell Lung Cancer
Pancreatic Cancer
Ovarian Cancer
Papillary Thyroid Cancer
Melanoma
Colorectal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT04729816 | COMPLETED | NA

17 participants

Assessing the Dose Response of a Lead Fiber Snack Prototype

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-02-22
Completion:: 2021-11-15

Conditions

Microbiota
Gastrointestinal Microbiome

Interventions

OTHER

No Results Yet

NCT04675476 | RECRUITING | NA

368 participants

A Patient and Provider Intervention to Address Health Disparities in Lung Cancer Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2024-03-11
Completion:: 2025-12-31

Conditions

Lung Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04660539 | COMPLETED | PHASE3

119 participants

A Study to Evaluate the Safety and Efficacy of Satralizumab in Participants With Neuromyelitis Optica Spectrum Disorder (NMOSD)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-03-02
Completion:: 2024-05-28

Conditions

Neuromyelitis Optica Spectrum Disorder

Interventions

DRUG

Results Available

NCT04659408 | COMPLETED | NA

14 participants

Probiotic and Prebiotic Supplementation in Elite Athletes with Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-03-01
Completion:: 2021-10-29

Conditions

Spinal Cord Injuries

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04623944 | ACTIVE_NOT_RECRUITING | PHASE1

61 participants

NKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-09-21
Completion:: 2024-10-02

Conditions

Relapsed/Refractory AML
AML, Adult
MDS
Refractory Myelodysplastic Syndromes

Interventions

BIOLOGICAL

No Results Yet

NCT04558983 | TERMINATED

32 participants

A Natural History Study to Evaluate Functional and Anatomical Progression in Retinitis Pigmentosa

Study Type:: OBSERVATIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-06-11
Completion:: 2024-12-20

Conditions

Retinitis Pigmentosa

No Results Yet

NCT04554953 | COMPLETED

10877 participants

A Combination Drug Including Fimasartan and Statins in Patients With Hypertension and Dyslipidemia

Study Type:: OBSERVATIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-04-13
Completion:: 2021-11-03

Conditions

Hypertension and Dyslipidemia

Interventions

DRUG

No Results Yet

NCT04541147 | TERMINATED | PHASE4

24 participants

Opioid & Steroid Use Following Tonsillectomy in Pediatric Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-04-14
Completion:: 2023-12-26

Conditions

Pain, Postoperative

Interventions

DRUG

Results Available

NCT04506866 | TERMINATED | NA

148 participants

InterStim Micro Post Market Clinical Follow-up Study (ELITE)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-08-25
Completion:: 2022-12-19

Conditions

Overactive Bladder
Fecal Incontinence
Non-obstructive Urinary Retention

Interventions

DEVICE

Results Available

NCT04500613 | COMPLETED | NA

24 participants

Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-02-22
Completion:: 2022-11-28

Conditions

Pain, Postoperative
Opioid Use
Recruitment

Interventions

PROCEDURE
OTHER

Results Available

NCT04485039 | COMPLETED | PHASE4

44 participants

Drug-drug Interaction Study of TPOXX When Co-administered With Phosphate Binders

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2022-06-08
Completion:: 2022-12-15

Conditions

Smallpox

Interventions

DRUG

Results Available

NCT04484428 | TERMINATED | PHASE2

126 participants

A Study to Evaluate the Efficacy and Safety of K-285 Compared With Menthol Gel for the Treatment of Delayed Onset Muscle Soreness (DOMS) in the Lower Extremity

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-08-15
Completion:: 2021-03-19

Conditions

Acute Pain

Interventions

DRUG

Results Available

NCT04470726 | COMPLETED | PHASE1/PHASE2

26 participants

Safety and Efficacy Evaluation of AIV001 in Nonmelanoma Skin Cancer of the Low Risk Basal Cell Carcinoma Subtype

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-08-18
Completion:: 2023-06-20

Conditions

Superficial Basal Cell Carcinoma
Nodular Basal Cell Carcinoma
Nonmelanoma Skin Cancers

Interventions

DRUG

No Results Yet

NCT04470011 | COMPLETED

2189 participants

Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-Zambia

Study Type:: OBSERVATIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-09-15
Completion:: 2021-04-30

Conditions

HIV
Antiretroviral Therapy

Interventions

OTHER

No Results Yet

NCT04468399 | COMPLETED

1781 participants

Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-Malawi

Study Type:: OBSERVATIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-05-21
Completion:: 2021-04-30

Conditions

HIV
Antiretroviral Therapy

Interventions

OTHER

No Results Yet

NCT04466241 | COMPLETED | PHASE2/PHASE3

294 participants

Combination Therapies to Reduce Carriage of SARS-Cov-2 and Improve Outcome of COVID-19 in Ivory Coast: a Phase Randomized IIb Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-11-27
Completion:: 2021-11-01

Conditions

COVID-19
COVID-19 Drug Treatment
Severe Acute Respiratory Syndrome Coronavirus 2

Interventions

DRUG

No Results Yet

NCT04436835 | COMPLETED | NA

21 participants

Psychotherapy (Accelerated Resolution Therapy) for Cancer Related Trauma and Distress

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2019-11-27
Completion:: 2021-08-19

Conditions

Hematopoietic and Lymphoid System Neoplasm
Malignant Solid Neoplasm

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT04422899 | COMPLETED | PHASE1

3 participants

Effect of Intravitreally Administered AIV007 in Subjects With Neovascular Age-Related Macular Degeneration

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-08-28
Completion:: 2021-09-29

Conditions

Neovascular Age-related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT04418466 | COMPLETED | PHASE1/PHASE2

34 participants

Safety, Tolerability, and Pharmacokinetics of Switching From Oral Risperidone to Risperidone Implant

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2021-04-01
Completion:: 2023-02-10

Conditions

Schizophrenia

Interventions

COMBINATION_PRODUCT

Results Available

NCT04396145 | ACTIVE_NOT_RECRUITING

30 participants

The Effects of Chronic Otitis Surgery on SVV

Study Type:: OBSERVATIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-04-29
Completion:: 2025-12-30

Conditions

Chronic Otitis Media

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04366310 | TERMINATED

65 participants

Capillary Refill Index with Rewarming

Study Type:: OBSERVATIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-11-16
Completion:: 2022-03-01

Conditions

Peripheral Perfusion

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT04263311 | COMPLETED | NA

195 participants

Scaling Community-Clinical Linkage Models to Address Diabetes and Hypertension Disparities in the Southeast United States

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-07-20
Completion:: 2021-09-30

Conditions

Hypertension

Interventions

BEHAVIORAL

Results Available

NCT04256941 | TERMINATED | PHASE2

4 participants

Aromatase Inhibitor Therapy With or Without Fulvestrant for the Treatment of HR Positive Metastatic Breast Cancer With an ERS1 Activating Mutation, the INTERACT Study

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2019-05-31
Completion:: 2023-09-22

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Breast Carcinoma
Prognostic Stage IV Breast Cancer AJCC v8

Interventions

DRUG

Results Available

NCT04233216 | COMPLETED | PHASE3

35 participants

Doravirine/Islatravir (DOR/ISL) in Heavily Treatment-Experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-03-18
Completion:: 2022-11-21

Conditions

HIV-1 Infection

Interventions

DRUG

Results Available

NCT04214990 | RECRUITING | PHASE3

1700 participants

Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-02-15
Completion:: 2031-03-31

Conditions

Aspirin
Gastric Cancer

Interventions

DRUG

No Results Yet

NCT04197869 | COMPLETED | PHASE4

71 participants

Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2019-12-09
Completion:: 2023-06-21

Conditions

Constipation
Post-Op Complication

Interventions

DRUG

Results Available

NCT04180202 | TERMINATED

8 participants

Comparison of Non-invasive Vs. Invasive Hemodynamic Measurements

Study Type:: OBSERVATIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-01-16
Completion:: 2022-06-20

Conditions

Heart Failure，Congestive

Interventions

DEVICE

No Results Yet

NCT04171999 | COMPLETED | NA

660 participants

CommunityRx-Hunger

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-01-06
Completion:: 2023-09-30

Conditions

Food Insecurity

Interventions

OTHER

Results Available

NCT04170374 | COMPLETED

831 participants

Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-South Africa

Study Type:: OBSERVATIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-11-01
Completion:: 2021-04-30

Conditions

HIV
Antiretroviral Therapy

Interventions

OTHER

No Results Yet

NCT04164069 | COMPLETED | PHASE1

9 participants

Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab

Study Type:: INTERVENTIONAL
Last Updated:: 2024-12-27
Start Date:: 2020-09-02
Completion:: 2023-06-22

Conditions

Advanced Colorectal Carcinoma
Metastatic Colorectal Carcinoma
Stage IV Colorectal Cancer AJCC v8
Stage IVA Colorectal Cancer AJCC v8
Stage IVB Colorectal Cancer AJCC v8
Stage IVC Colorectal Cancer AJCC v8
Stage II Colon Cancer
Stage II Rectal Cancer
Stage III Colon Cancer
Stage III Rectal Cancer
Esophageal Cancer
Pancreatic Cancer
Bile Duct Cancer
Gastric Cancer
Gall Bladder Cancer
Small Bowel Adenocarcinoma

Interventions

BIOLOGICAL
DRUG
OTHER

No Results Yet