Clinical Trials

NCT05480865 | TERMINATED | PHASE1

28 participants

SHP2 Inhibitor BBP-398 in Combination With Sotorasib in Patients With Advanced Solid Tumors and a KRAS-G12C Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-07-06

Completion:

2024-08-22

Conditions

• Solid Tumor, Adult
• Metastatic Solid Tumor
• Metastatic NSCLC
• Non Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05454254 | COMPLETED | NA

20 participants

Effect of Muscle Strengthening Training in Adults with Fontan Circulation

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-08-15

Completion:

2023-11-30

Conditions

• Congenital Heart Disease
• Univentricular Heart

Interventions

• OTHER

No Results Yet

NCT05451251 | RECRUITING | PHASE1

6 participants

Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2024-10-15

Completion:

2025-10-15

Conditions

• Trigeminal Neuralgia

Interventions

• DEVICE

No Results Yet

NCT05450185 | RECRUITING

600 participants

Filter Lifespan in Continuous Renal Replacement Therapy

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2023-03-02

Completion:

2025-05-31

Conditions

• Critically Ill
• Continuous Renal Replacement Therapy
• Infections

Interventions

• PROCEDURE

No Results Yet

NCT05375084 | TERMINATED | PHASE1

21 participants

SHP2 Inhibitor BBP-398 in Combination With Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer With a KRAS Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-10-20

Completion:

2024-04-12

Conditions

• Non Small Cell Lung Cancer
• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05356806 | RECRUITING

277 participants

Incidence of Peri-implant Mucositis in Patients With Treated Periodontitis

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2022-01-10

Completion:

2025-12-31

Conditions

• Peri-implant Mucositis

Interventions

• OTHER

No Results Yet

NCT05345769 | COMPLETED | PHASE1

21 participants

Safety and Efficacy of AM712 in Patients with NAMD

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-04-28

Completion:

2024-11-04

Conditions

• Neovascular Age-related Macular Degeneration

Interventions

• BIOLOGICAL

No Results Yet

NCT05339529 | RECRUITING | NA

330 participants

Protective Effect of Thymosin Α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA II)

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-07-01

Completion:

2025-12-31

Conditions

• Acute Aortic Syndrome
• Aortic Dissection Type a

Interventions

• DRUG

No Results Yet

NCT05335317 | RECRUITING | NA

120 participants

Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-04-18

Completion:

2025-09-01

Conditions

• Postmenopausal Period
• Vaginal Atrophy
• Vaginal Prolapse

Interventions

• DEVICE
• DRUG
• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT05324280 | RECRUITING | NA

68 participants

Acupuncture in a Multidisciplinary Approach for Vulvodynia and Chronic Pelvic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-06-23

Completion:

2026-01-31

Conditions

• Vulvodynia
• Chronic Pelvic Pain

Interventions

• PROCEDURE

No Results Yet

NCT05320068 | COMPLETED | PHASE3

24 participants

Oral Vancomycin Vs Placebo in the Prevention of Recurrence of Clostridioides Difficile's Infection

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-08-02

Completion:

2024-03-01

Conditions

• Clostridioides Difficile Infection

Interventions

• DRUG

No Results Yet

NCT05276622 | TERMINATED

64 participants

Patient and Care Partner Experiences Living With Multiple Myeloma (PaCE-MM)

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2022-02-08

Completion:

2023-10-03

Conditions

• Multiple Myeloma

Interventions

• OTHER

No Results Yet

NCT05207722 | TERMINATED | PHASE1/PHASE2

1 participants

CYNK-101 in Combination with Trastuzumab and Pembrolizumab in Patients with Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-04-14

Completion:

2024-02-15

Conditions

• Metastatic HER2 Positive Gastroesophageal Junction Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05159349 | RECRUITING

1200 participants

Mental Health During the Whole Life Cycle of Community Patients with Schizophrenia

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2021-12-01

Completion:

2025-12-31

Conditions

• Schizophrenia

No Results Yet

NCT05122533 | COMPLETED

100 participants

Reliability of Clinical Limb-length Measurements Methods

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2021-10-01

Completion:

2022-06-30

Conditions

• Leg Length Inequality

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05094544 | WITHDRAWN | NA

0 participants

Pre-Operative Immuno-Modulatory SBRT (POIMS Trial): A Pilot Trial in Early Stage NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-10-01

Completion:

2023-03-23

Conditions

• Non-small Cell Lung Cancer

Interventions

• RADIATION

No Results Yet

NCT05086341 | COMPLETED | NA

22 participants

A Pilot- and Feasibility Trial of the EHealth Tool My COPD for People with COPD

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-11-05

Completion:

2023-10-01

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

• DEVICE

No Results Yet

NCT05070468 | COMPLETED | PHASE3

84 participants

Effect of Dexamethasone on Labor Induction

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2020-11-22

Completion:

2021-01-21

Conditions

• Dexamethasone
• Pregnancy

Interventions

• DRUG

Results Available

NCT05055934 | COMPLETED | PHASE2

112 participants

Study of the Effectiveness and Safety of SHR-1314 for Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-10-22

Completion:

2024-06-05

Conditions

• Psoriatic Arthritis

Interventions

• DRUG

No Results Yet

NCT05036044 | COMPLETED

1002 participants

Stroke and Carotid-Cerebral Vascular Disease After CABG

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2021-09-04

Completion:

2023-01-21

Conditions

• Coronary Artery Bypass

No Results Yet

NCT05020899 | COMPLETED | NA

109 participants

Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2022-02-24

Completion:

2023-08-01

Conditions

• Smoking Cessation
• HIV Infections

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT05015543 | COMPLETED | NA

54 participants

Physical Training in Glioblastoma Patients During Cytotoxic Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2020-07-23

Completion:

2024-10-17

Conditions

• Glioblastoma

Interventions

• OTHER

No Results Yet

NCT05000957 | ACTIVE_NOT_RECRUITING | NA

129 participants

Pelvic Organs Prolapse Treatment Using Neodymium Laser

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-10-03

Completion:

2025-04-01

Conditions

• Pelvic Organ Prolapse
• Female Urogenital Diseases

Interventions

• DEVICE
• DIAGNOSTIC_TEST
• PROCEDURE
• OTHER
• GENETIC

No Results Yet

NCT04996758 | COMPLETED | PHASE2

40 participants

Toripalimab and Anlotinib Combination Treatment in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma After Failure of at Least One Line of Platinum-Based Chemotherapy (TORAL)

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-10-30

Completion:

2023-09-30

Conditions

• Nasopharyngeal Carcinoma
• Recurrent or Metastatic Nasopharyngeal Carcinoma

Interventions

• DRUG

No Results Yet

NCT04977362 | COMPLETED | NA

201 participants

Interdisciplinary Perioperative Care in Minimally-invasive Heart Valve Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-07-01

Completion:

2024-03-24

Conditions

• Heart Valve Diseases

Interventions

• OTHER

No Results Yet

NCT04946019 | COMPLETED | PHASE2

55 participants

MR-Linac Guided Adaptive FSRT for Brain Metastases From Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-06-01

Completion:

2024-07-17

Conditions

• Non-small Cell Lung Cancer

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04935086 | COMPLETED

370 participants

Risk Factors for Predictors of MACEs After RA-CABG

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2021-06-30

Completion:

2021-11-30

Conditions

• Coronary Artery Disease

No Results Yet

NCT04891419 | COMPLETED | PHASE3

168 participants

JUVÉDERM® VOLUMA® With Lidocaine for Correction of Temple Hollowing in Chinese Population

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-07-20

Completion:

2023-11-22

Conditions

• Temple Hollowing

Interventions

• DEVICE

Results Available

NCT04859504 | COMPLETED | NA

60 participants

Developing Dual-channel Transcranial Alternating Current Stimulations Targeting Negative Symptoms in Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-04-01

Completion:

2024-07-31

Conditions

• Schizophrenia
• Transcranial Alternating Current Stimulations
• Negative Symptoms

Interventions

• DEVICE

No Results Yet

NCT04856722 | COMPLETED | NA

255 participants

Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-04-05

Completion:

2024-06-04

Conditions

• Renal Stone
• Percutaneous Nephrolithotomy
• Retrograde Intrarenal Surgery
• Extracorporeal Shockwave Lithotripsy

Interventions

• PROCEDURE

No Results Yet

NCT04794010 | ACTIVE_NOT_RECRUITING

825 participants

A Study in Participants With First-Line Nivolumab Plus Ipilimumb Therapy Combined With Two Cycles of Chemotherapy for Metastatic Non-Small Cell Lung Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2020-12-22

Completion:

2027-12-22

Conditions

• Carcinoma, Non-Small-Cell Lung

No Results Yet

NCT04767854 | ACTIVE_NOT_RECRUITING | NA

68 participants

Digital Osteoarthritis Care

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-06-01

Completion:

2023-12-31

Conditions

• Osteoarthritis

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04757233 | COMPLETED | NA

20 participants

Personalizing Self-management in Diabetes - Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2018-02-01

Completion:

2018-04-30

Conditions

• Type 2 Diabetes Mellitus

Interventions

• BEHAVIORAL

No Results Yet

NCT04735549 | COMPLETED | NA

120 participants

Vulvovaginal Atrophy Correction Using Neodymium Laser

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-09-01

Completion:

2023-10-20

Conditions

• Postmenopausal Period
• Vaginal Atrophy
• Female Urogenital Diseases

Interventions

• DEVICE
• DRUG
• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT04717388 | RECRUITING | NA

300 participants

Pathophysiology, Psycho-emotional and Cognitive Functioning Associated With Tinnitus

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-06-15

Completion:

2027-10-15

Conditions

• Tinnitus
• Epilepsy, Temporal Lobe

Interventions

• OTHER
• RADIATION

No Results Yet

NCT04714762 | ACTIVE_NOT_RECRUITING | NA

200 participants

eHealth in Treatment of Gestational Diabetes (eMOMGDM)

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2021-03-10

Completion:

2022-12-12

Conditions

• Gestational Diabetes
• Mobile Application

Interventions

• DEVICE

No Results Yet

NCT04633603 | ENROLLING_BY_INVITATION

10000 participants

LázBarát™ (FeverFriend™) Projekt: Attitude Toward Fever and Its Change in the Healthcare System

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2020-01-15

Completion:

2028-01-15

Conditions

• Fever
• Anxiety
• Help-Seeking Behavior
• Virus Diseases
• Bacterial Infections
• Overdose of Analgesic Drug

Interventions

• DEVICE

No Results Yet

NCT04607980 | COMPLETED | PHASE3

563 participants

A Study to Investigate ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2020-11-11

Completion:

2022-01-13

Conditions

• Plaque Psoriasis

Interventions

• DRUG

Results Available

NCT04541602 | TERMINATED

5 participants

Detection of Neuromuscular Complications in Critically Ill Patients

Study Type:

OBSERVATIONAL

Last Updated:

2024-12-12

Start Date:

2020-09-01

Completion:

2024-12-08

Conditions

• Critical Illness
• Dysphagia
• Intensive Care Unit Acquired Weakness
• Neuromuscular Diseases

No Results Yet

NCT04528836 | TERMINATED | PHASE1

72 participants

First-in-Human Study of the SHP2 Inhibitor BBP-398 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2024-12-12

Start Date:

2020-11-12

Completion:

2024-03-22

Conditions

• Tumor, Solid

Interventions

• DRUG

No Results Yet