Clinical Trials

NCT04405180 | COMPLETED | PHASE2

64 participants

Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2021-04-23

Completion:

2023-07-14

Conditions

• Aging
• Sedentary Lifestyle
• Frailty

Interventions

• DRUG

Results Available

NCT04387773 | COMPLETED | PHASE4

8 participants

Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2020-11-05

Completion:

2022-09-01

Conditions

• Parkinson Disease

Interventions

• DRUG

Results Available

NCT04311983 | COMPLETED | NA

1973 participants

Interventions to Help More Low-income Smokers Quit

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2020-03-31

Completion:

2023-09-29

Conditions

• Tobacco Use Cessation
• Smoking Behaviors
• Health Disparity

Interventions

• BEHAVIORAL

Results Available

NCT04304833 | TERMINATED | NA

26 participants

Innovative Care of Older Adults With Chronic Heart Failure: A Comparative Effectiveness Clinical Trial (I-COACH)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2020-11-17

Completion:

2021-10-25

Conditions

• Heart Failure

Interventions

• OTHER
• BEHAVIORAL

Results Available

NCT04240405 | COMPLETED

42 participants

Effects of Episodic Specificity Induction in Normal and Pathological Ageing.

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-10

Start Date:

2019-12-11

Completion:

2024-04-19

Conditions

• Neurocognitive Disorders

No Results Yet

NCT04224155 | COMPLETED | NA

165 participants

Clinical Study to Evaluate the Safety and Performance of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens in Subjects Undergoing Cataract Extraction

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2020-03-10

Completion:

2022-06-14

Conditions

• Cataract

Interventions

• DEVICE

Results Available

NCT04212299 | COMPLETED | NA

5 participants

Transfemoral Socket Design and Muscle Function

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-09-24

Completion:

2022-09-23

Conditions

• Amputation

Interventions

• DEVICE

Results Available

NCT04198662 | COMPLETED | PHASE4

20 participants

Rib Fracture Analgesia Using Cryoanalgesia

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2020-04-03

Completion:

2023-08-28

Conditions

• Traumatic Rib Fracture(s)

Interventions

• DEVICE
• DRUG

Results Available

NCT04195789 | COMPLETED

34 participants

Assessment of Interstitial Lung Disease in Rheumatoid Arthritis by Lung Ultrasound

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-10

Start Date:

2020-08-04

Completion:

2024-05-04

Conditions

• Lung Diseases
• Lung Diseases, Interstitial
• Rheumatoid Arthritis

Interventions

• OTHER

No Results Yet

NCT04195503 | ENROLLING_BY_INVITATION | NA

10 participants

Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-12-10

Completion:

2029-12-31

Conditions

• Cholangiocarcinoma, Intrahepatic

Interventions

• PROCEDURE

No Results Yet

NCT04118530 | COMPLETED

21 participants

Long Term Arrhythmia Risk and Cardiovascular Events in Hematopoietic Stem Cell Transplant

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-10

Start Date:

2021-04-21

Completion:

2024-06-17

Conditions

• Hematopoietic Stem Cell Transplant
• Atrial Fibrillation
• Atrial Flutter

Interventions

• OTHER

No Results Yet

NCT04088097 | COMPLETED | NA

50 participants

Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-12-30

Completion:

2023-10-17

Conditions

• Binge Eating
• Eating Disorders in Adolescence
• Overweight and Obesity

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT04060394 | COMPLETED | PHASE1/PHASE2

49 participants

Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-09-13

Completion:

2023-12-27

Conditions

• Metastatic Castration-resistant Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04040985 | TERMINATED | NA

128 participants

LEGION™ Primary Safety and Efficacy

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2009-09-09

Completion:

2020-12-17

Conditions

• Osteo Arthritis Knee
• Total Knee Replacement

Interventions

• PROCEDURE

Results Available

NCT04039672 | COMPLETED | NA

10 participants

Interest of Tumor Replicates in Avian Embryo to Model Therapeutic Effects of BRAFi/MEKi in BRAF Mutated Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2021-04-02

Completion:

2024-07-02

Conditions

• Melanoma

Interventions

• PROCEDURE

No Results Yet

NCT04021277 | TERMINATED | PHASE1

11 participants

PS101-mediated ACT With Chemotherapy in Liver Metastases From Cancer of Gastrointestinal Origin

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-09-17

Completion:

2024-08-27

Conditions

• Solid Tumor
• Colorectal Cancer

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04005183 | COMPLETED

146 participants

Renal Cell Carcinoma Microenvironment Discovery Project

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-10

Start Date:

2019-05-06

Completion:

2023-07-20

Conditions

• Renal Cell Carcinoma

No Results Yet

NCT03998618 | COMPLETED | NA

250 participants

Telephone Support for Metastatic Breast Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-06-20

Completion:

2023-09-13

Conditions

• Metastatic Breast Cancer

Interventions

• BEHAVIORAL

Results Available

NCT03996473 | TERMINATED | PHASE1

8 participants

Study to Test the Safety and How Radium-223 Dichloride an Alpha Particle-emitting Radioactive Agent Works in Combination With Pembrolizumab an Immune Checkpoint Inhibitor in Patients With Stage IV Non-small Cell Lung Cancer With Bone Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2020-03-06

Completion:

2021-04-14

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT03989466 | COMPLETED | PHASE1

15 participants

Itacitinib and Alemtuzumab in Treating Patients With T-Cell Prolymphocytic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2020-01-15

Completion:

2024-09-24

Conditions

• Recurrent T-Cell Prolymphocytic Leukemia
• T-Cell Prolymphocytic Leukemia

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03923959 | COMPLETED | PHASE3

283 participants

Evaluation of TXA Prior to Surgery in the Geriatric Hip Fracture Population

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2020-02-01

Completion:

2022-12-09

Conditions

• Hip Fractures

Interventions

• DRUG
• OTHER

Results Available

NCT03879798 | TERMINATED | PHASE1/PHASE2

22 participants

DS-3201b and Irinotecan for Patients With Recurrent Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-03-15

Completion:

2023-05-02

Conditions

• Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT03821376 | TERMINATED | PHASE4

12 participants

Correlation of Renal Mass Pathologic Grade and Contrast Enhanced Ultrasound (CEUS)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-07-16

Completion:

2021-09-21

Conditions

• Renal Malignant Tumor

Interventions

• DRUG

Results Available

NCT03820661 | ACTIVE_NOT_RECRUITING | NA

30 participants

High Resolution Ultrasound in Pancreatic Ductal Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-02-01

Completion:

2026-12-31

Conditions

• Pancreatic Ductal Adenocarcinoma

Interventions

• DEVICE

No Results Yet

NCT03760237 | COMPLETED

84 participants

Cardiovascular Function in Acute Leukemia

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-10

Start Date:

2018-12-10

Completion:

2024-05-06

Conditions

• Leukemia, Myeloid, Acute
• Leukemia, Lymphoid, Acute
• Cardiotoxicity

Interventions

• OTHER

No Results Yet

NCT03710915 | TERMINATED | PHASE1

3 participants

A Study of HG146 Capsule in Chinese Subjects with Relapsed and Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-01-12

Completion:

2022-09-28

Conditions

• Multiple Myeloma
• Relapsed and Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT03620474 | COMPLETED | PHASE1/PHASE2

27 participants

Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2018-07-24

Completion:

2021-07-13

Conditions

• Hepatitis C
• Hepatitis B
• Liver Cirrhoses

Interventions

• DRUG

No Results Yet

NCT03579563 | COMPLETED | NA

290 participants

Impact of Hearing Aid Service-delivery Model and Technology on Patient Outcomes

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-02-22

Completion:

2023-12-22

Conditions

• Presbycusis

Interventions

• OTHER
• DEVICE

Results Available

NCT03555396 | COMPLETED | NA

132 participants

Couples ART Adherence Intervention for PWID in Kazakhstan

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2020-10-26

Completion:

2023-03-09

Conditions

• HIV Infections
• Substance Use Disorders

Interventions

• BEHAVIORAL

Results Available

NCT03541369 | TERMINATED | PHASE1

64 participants

Safety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2018-09-14

Completion:

2023-02-21

Conditions

• Relapsed/Refractory Acute Myeloid Leukemia (AML)

Interventions

• DRUG

Results Available

NCT03370887 | COMPLETED | PHASE2

11 participants

AZD8601 Study in CABG Patients

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2018-02-05

Completion:

2021-06-30

Conditions

• Heart Failure

Interventions

• DRUG

Results Available

NCT03321019 | COMPLETED

119 participants

Airway Protective Mechanisms in PD (R01)

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-10

Start Date:

2017-12-12

Completion:

2023-07-29

Conditions

• Parkinson Disease

Interventions

• DRUG
• DEVICE
• OTHER
• PROCEDURE

Results Available

NCT03207529 | COMPLETED | PHASE1

18 participants

Alpelisib and Enzalutamide in Treating Patients With Androgen Receptor and PTEN Positive Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2019-06-07

Completion:

2023-12-31

Conditions

• Advanced Breast Carcinoma
• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IIIA Breast Cancer AJCC v8
• Anatomic Stage IIIB Breast Cancer AJCC v8
• Anatomic Stage IIIC Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Androgen Receptor Positive
• HER2/Neu Negative
• Metastatic Breast Carcinoma
• Prognostic Stage III Breast Cancer AJCC v8
• Prognostic Stage IIIA Breast Cancer AJCC v8
• Prognostic Stage IIIB Breast Cancer AJCC v8
• Prognostic Stage IIIC Breast Cancer AJCC v8
• Prognostic Stage IV Breast Cancer AJCC v8
• PTEN Positive
• Recurrent Breast Carcinoma
• Refractory Breast Carcinoma
• Triple-Negative Breast Carcinoma

Interventions

• DRUG

No Results Yet

NCT03165526 | COMPLETED

131 participants

The AMPLATZER™ Post-infarct Muscular VSD Occluder Humanitarian Device Exemption (H070005) Post Approval Study

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-10

Start Date:

2018-10-01

Completion:

2021-11-29

Conditions

• Post-Infarction Ventricular Septal Defect

Interventions

• DEVICE

Results Available

NCT03087591 | COMPLETED | PHASE1

11 participants

APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2017-04-28

Completion:

2019-07-31

Conditions

• Metastatic Malignant Neoplasm in the Brain
• Metastatic Solid Neoplasm
• Recurrent Colorectal Carcinoma
• Recurrent Pancreatic Carcinoma
• Recurrent Solid Neoplasm
• Stage IV Colorectal Cancer
• Stage IV Pancreatic Cancer
• Stage IVA Colorectal Cancer
• Stage IVA Pancreatic Cancer
• Stage IVB Colorectal Cancer
• Stage IVB Pancreatic Cancer
• Unresectable Solid Neoplasm

Interventions

• OTHER
• BIOLOGICAL

Results Available

NCT03070301 | COMPLETED | PHASE2

21 participants

A Study of LEE011 With Everolimus in Patients With Advanced Neuroendocrine Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2017-02-27

Completion:

2024-01-31

Conditions

• Neuroendocrine Tumors

Interventions

• DRUG

Results Available

NCT02950493 | TERMINATED | NA

20 participants

Use of Reactivated DEFINITY or LUMASON in Patients Undergoing Rest or Stress Echocardiography

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2017-04-06

Completion:

2024-09-30

Conditions

• Stress Echocardiography

Interventions

• OTHER

No Results Yet

NCT02758431 | COMPLETED | NA

232 participants

Cardiovascular Outcomes of Low Testosterone

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2016-07-01

Completion:

2023-01-04

Conditions

• Hypogonadism

Interventions

• DRUG

No Results Yet

NCT02692248 | COMPLETED | PHASE2

64 participants

Ibrutinib in Patients With Refractory/Relapsed Non-GCB Diffuse Large B-cell Lymphoma Non-candidates to ASCT

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2016-04-07

Completion:

2018-11-08

Conditions

• Diffuse Large B-Cell Lymphoma

Interventions

• DRUG

Results Available

NCT02555397 | COMPLETED | PHASE1

15 participants

Phase 1 Trial of Interleukin 12 Gene Therapy for Locally Recurrent Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-10

Start Date:

2015-08-31

Completion:

2019-06-16

Conditions

• Prostate Cancer

Interventions

• BIOLOGICAL

Results Available