Clinical Trials

NCT04820530 | COMPLETED | PHASE3

40 participants

Study of Efficacy and Safety of Twice Daily Oral Iptacopan (LNP023) in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-07-19

Completion:

2022-11-02

Conditions

• Paroxysmal Nocturnal Hemoglobinuria (PNH)

Interventions

• DRUG

Results Available

NCT04820205 | COMPLETED | NA

136 participants

Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Procedural Sedation in Children

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-10-29

Completion:

2024-03-05

Conditions

• Sedation

Interventions

• DRUG

No Results Yet

NCT04807400 | COMPLETED | PHASE3

892 participants

Study in Primary Care Evaluating Inclisiran Delivery Implementation + Enhanced Support

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-07-07

Completion:

2023-01-13

Conditions

• Atherosclerotic Cardiovascular Disease
• Atherosclerotic Cardiovascular Disease Risk Equivelents
• Elevated Low Density Lipoprotein Cholesterol

Interventions

• DRUG
• BEHAVIORAL

Results Available

NCT04784533 | COMPLETED | PHASE2

317 participants

A Study to Evaluate the Durability of Response of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-02-26

Completion:

2023-05-16

Conditions

• Alopecia Areata

Interventions

• DRUG

Results Available

NCT04780204 | ACTIVE_NOT_RECRUITING | PHASE4

600 participants

Effectiveness of Antiviral Treatment in Cirrhotic Patients with Low-level Hepatitis B Virus DNA Levels

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-08-23

Completion:

2027-01-31

Conditions

• Hepatitis B, Chronic

Interventions

• DRUG

No Results Yet

NCT04773587 | COMPLETED | PHASE3

654 participants

Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-01-27

Completion:

2022-08-30

Conditions

• Atopic Dermatitis Eczema

Interventions

• DRUG

Results Available

NCT04746794 | COMPLETED | NA

20184 participants

Early Detection of GEnetic Risk (EDGE)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-09-25

Completion:

2023-05-31

Conditions

• Genetic Predisposition

Interventions

• BEHAVIORAL

Results Available

NCT04711902 | COMPLETED | PHASE3

41 participants

Study of Efficacy and Safety of Secukinumab in Chinese Subjects With Active PsA Compared to Placebo.

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-06-24

Completion:

2022-06-02

Conditions

• Psoriatic Arthritis

Interventions

• DRUG
• OTHER

Results Available

NCT04709211 | COMPLETED | NA

128 participants

Fascia Iliaca Compartment Block Versus Anterior Quadratus Lumborum Block

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-01-10

Completion:

2021-06-30

Conditions

• Postoperative Pain

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04667117 | COMPLETED | PHASE4

63 participants

A Multicenter Study to Assess Response to Influenza Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-01-14

Completion:

2023-07-06

Conditions

• Relapsing Multiple Sclerosis

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04660331 | COMPLETED | NA

42 participants

Communication Strategy to PROMOTE HPV Vaccination in Pharmacies: PROMOTE Study

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-02-01

Completion:

2023-07-31

Conditions

• Human Papillomavirus Infection

Interventions

• OTHER
• BEHAVIORAL

Results Available

NCT04630158 | COMPLETED | PHASE2

153 participants

Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-04-21

Completion:

2023-06-07

Conditions

• Chronic Ocular Pain

Interventions

• OTHER
• DRUG

Results Available

NCT04598750 | RECRUITING

250 participants

The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2021-06-15

Completion:

2025-12-31

Conditions

• Neonatal Thrombocytopenia
• Bleeding

No Results Yet

NCT04597632 | COMPLETED | PHASE3

248 participants

An Extension Study Assessing the Efficacy and Safety of Brolucizumab in a Treat-to-Control Regimen in Patients With Neovascular Age-related Macular Degeneration Who Have Completed the CRTH258A2303 (TALON) Study

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-12-16

Completion:

2023-03-28

Conditions

• Neovascular Age-related Macular Degeneration

Interventions

• DRUG

Results Available

NCT04581941 | COMPLETED

4 participants

Deep Brain Stimulation Effects in Essential Tremor

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2020-12-05

Completion:

2024-05-30

Conditions

• Essential Tremor

No Results Yet

NCT04576169 | RECRUITING | NA

204 participants

Trial Comparing Treatment Strategies in Triangular Fibrocartilage Complex Ruptures

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-10-27

Completion:

2028-03-31

Conditions

• Triangular Fibrocartilage Complex Injury

Interventions

• PROCEDURE

No Results Yet

NCT04575064 | WITHDRAWN | PHASE2/PHASE3

0 participants

An International Randomized Trial of Additional Treatments for COVID-19 in Hospitalized Patients Who Are All Receiving the Local Standard of Care - WHO-SOLIDARITY-GERMANY

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-06-29

Completion:

2022-03-31

Conditions

• SARS-CoV-2 Infection
• COVID-19
• Moderate and Severe COVID-19

Interventions

• OTHER
• DRUG

No Results Yet

NCT04558918 | COMPLETED | PHASE3

97 participants

Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-01-25

Completion:

2022-09-26

Conditions

• Paroxysmal Nocturnal Hemoglobinuria (PNH)

Interventions

• DRUG

Results Available

NCT04522817 | WITHDRAWN | PHASE1

0 participants

CLBS119 for Repair of COVID-19 Induced Pulmonary Damage

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-10-05

Completion:

2021-05-31

Conditions

• Covid-19

Interventions

• BIOLOGICAL

No Results Yet

NCT04505956 | COMPLETED | NA

171 participants

A Comparison of Ureteroscopic Treatment of Nephrolithiasis With and Without Moses Technology

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-01-13

Completion:

2023-08-01

Conditions

• Nephrolithiasis

Interventions

• DEVICE

Results Available

NCT04488536 | ACTIVE_NOT_RECRUITING

10000 participants

Management and Outcomes of Patients Admitted to Coronary Care Units, Depending on Degree of Frailty and Comorbidities

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2020-07-29

Completion:

2021-12-31

Conditions

• Myocardial Infarction
• Frailty

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04460560 | COMPLETED | PHASE3

50 participants

Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-12-11

Completion:

2023-12-27

Conditions

• Hepatorenal Syndrome

Interventions

• DRUG

Results Available

NCT04428333 | TERMINATED | PHASE3

117 participants

Study of GSK3359609 With Pembrolizumab and 5-fluorouracil (5-FU)-Platinum Chemotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-08-12

Completion:

2021-04-27

Conditions

• Neoplasms, Head and Neck

Interventions

• DRUG

Results Available

NCT04345601 | COMPLETED | PHASE1/PHASE2

28 participants

Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-02-12

Completion:

2023-01-10

Conditions

• Sars-CoV2
• Acute Respiratory Distress Syndrome
• COVID-19

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04335903 | COMPLETED

248 participants

The Turkish Version of the Vividness of Visual Imagery Questionnaire-2

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2021-08-21

Completion:

2021-10-21

Conditions

• Body Image
• Assessment, Self

No Results Yet

NCT04323436 | TERMINATED | PHASE2

31 participants

Study of Capmatinib and Spartalizumab/Placebo in Advanced NSCLC Patients With MET Exon 14 Skipping Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-08-19

Completion:

2022-12-14

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT04308226 | COMPLETED | NA

261 participants

Lung Cancer Screening Navigation for Homeless People

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-11-20

Completion:

2023-02-06

Conditions

• Lung Cancer
• Tobacco Use
• Homelessness

Interventions

• BEHAVIORAL

Results Available

NCT04271930 | TERMINATED | NA

24 participants

Effect of Sleep Quality on Hematopoietic Cell Transplant Patient Outcomes

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-11-01

Completion:

2023-05-23

Conditions

• Sleep
• Multiple Myeloma

Interventions

• BEHAVIORAL

No Results Yet

NCT04239027 | COMPLETED | PHASE3

210 participants

A Study to Assess the Effects of Brolucizumab in Adult Patients With Neovascular Age Related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2021-01-26

Completion:

2022-05-23

Conditions

• Neovascular Age Related Macular Degeneration

Interventions

• DRUG

Results Available

NCT04190537 | COMPLETED

749 participants

PARADOX - the Incidence of Paradoxical Reactions in Pediatric Patients Premedicated with Midazolam

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2019-09-01

Completion:

2021-06-16

Conditions

• Pharmacological Action

No Results Yet

NCT04159688 | COMPLETED | EARLY_PHASE1

8 participants

Imaging Glutamate Release From Alcohol

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-03-01

Completion:

2022-06-30

Conditions

• Alcohol Drinking

Interventions

• DRUG

Results Available

NCT04154787 | TERMINATED | PHASE2

37 participants

Efficacy and Safety of LNP023 Compared With Rituximab in Subjects With Idiopathic Membranous Nephropathy

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-11-23

Completion:

2023-01-20

Conditions

• Idiopathic Membranous Nephropathy

Interventions

• DRUG

Results Available

NCT04139317 | TERMINATED | PHASE2

76 participants

Safety and Efficacy of Capmatinib (INC280) Plus Pembrolizumab vs Pembrolizumab Alone in NSCLC With PD-L1≥ 50%

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-01-22

Completion:

2022-01-14

Conditions

• Non-small Cell Lung Cancer (NSCLC)

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04138823 | COMPLETED | PHASE1

12 participants

A Study to Test Different Doses of BI 891065 Alone and in Combination With BI 754091 in Asian Patients With Different Types of Advanced Cancer (Solid Tumours)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-11-26

Completion:

2023-05-17

Conditions

• Neoplasm

Interventions

• DRUG

Results Available

NCT04135326 | WITHDRAWN | EARLY_PHASE1

0 participants

Transcranial Direct Current Stimulation in Reducing Pain in Cancer Patients With Chemotherapy Induced Peripheral Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-10-10

Completion:

2020-10-26

Conditions

• Chemotherapy-Induced Peripheral Neuropathy
• Malignant Neoplasm

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT04129229 | ENROLLING_BY_INVITATION | NA

80 participants

LinguaFlex Tongue Retractor (LTR) for the Treatment of OSA and Snoring in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-01-10

Completion:

2025-12-31

Conditions

• Obstructive Sleep Apnea
• Snoring

Interventions

• DEVICE

No Results Yet

NCT04106661 | COMPLETED | NA

17 participants

Tai Chi as Physical Activity for Women With Morbid Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2016-09-02

Completion:

2017-11-21

Conditions

• Morbid Obesity

Interventions

• OTHER

Results Available

NCT04084314 | COMPLETED | PHASE4

701 participants

Assessment of Prolonged Safety and tOLerability of in Migraine Patients in a Long-term OpeN-label Study

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-09-30

Completion:

2023-02-23

Conditions

• Migraine
• Migraine Disorders
• Migraine Headache

Interventions

• BIOLOGICAL

Results Available

NCT04066114 | COMPLETED | PHASE1/PHASE2

24 participants

Treg Modulation With CD28 and IL-6 Receptor Antagonists

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-12-11

Completion:

2023-09-14

Conditions

• Living-Donor Kidney Transplant
• Kidney Transplant Recipients

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04065438 | RECRUITING | NA

35 participants

Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-01-01

Completion:

2026-04-01

Conditions

• Focal Segmental Glomerulosclerosis

Interventions

• DEVICE

No Results Yet