Clinical Trials Updated in 2024

NCT04743804 | TERMINATED | PHASE3

16 participants

Ravulizumab in Thrombotic Microangiopathy Associated With a Trigger

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-06-29
Completion:: 2022-12-22

Conditions

Thrombotic Microangiopathy

Interventions

BIOLOGICAL
OTHER

Results Available

NCT04739722 | COMPLETED | NA

14263 participants

Colorectal Cancer and Pre-Cancerous Adenoma Non-Invasive Detection Test Study

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-04-12
Completion:: 2022-10-27

Conditions

Colorectal Cancer
Advanced Adenocarcinoma
Serrated Polyp

Interventions

DIAGNOSTIC_TEST

Results Available

NCT04712019 | TERMINATED | NA

10 participants

Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-11-06
Completion:: 2022-08-26

Conditions

Surgical Wound
Bilateral Total Knee Arthroplasty
Wounds and Injuries
Joint Diseases
Musculoskeletal Diseases
Edema Leg
Joint Pain
Arthritis Knee

Interventions

DEVICE

Results Available

NCT04696354 | TERMINATED | NA

12 participants

Intravascular Ultrasound-Guided Intervention for Venous Leg Ulcers (IGuideU)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-10-12
Completion:: 2023-01-11

Conditions

Venous Ulcer of Leg

Interventions

DIAGNOSTIC_TEST
OTHER

Results Available

NCT04677751 | RECRUITING | NA

10 participants

Clinical and Electrographic Changes in Responsive Neurostimulation System (RNS) Patients with Acupuncture Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-04-01
Completion:: 2025-12-01

Conditions

Epilepsy

Interventions

DEVICE

No Results Yet

NCT04659629 | COMPLETED | PHASE1

59 participants

NL-201 Monotherapy and in Combination With Pembrolizumab in Patients With Relapsed or Refractory Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-04-26
Completion:: 2022-12-15

Conditions

Solid Tumor
Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT04601103 | TERMINATED | NA

53 participants

3M Oral Rinse Incidence and Patient Acceptance of Sloughing When Used With Sodium Lauryl Sulfate (SLS) Toothpastes

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-01-06
Completion:: 2020-03-10

Conditions

Oral Mucosal Disorder

Interventions

DRUG
DEVICE

Results Available

NCT04598451 | COMPLETED | PHASE3

222 participants

A Study to Assess the Efficacy and Safety of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-12-01
Completion:: 2023-08-22

Conditions

Pemphigus Vulgaris
Pemphigus Foliaceus

Interventions

BIOLOGICAL
OTHER
DRUG

Results Available

NCT04579445 | COMPLETED

2408 participants

Setting a Benchmark for Resource Utilization and Quality of Care in Patients Undergoing TAVI in Europe

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-05-03
Completion:: 2023-04-30

Conditions

Transcatheter Aortic Valve Implantation (TAVI)

Interventions

OTHER

No Results Yet

NCT04567368 | ACTIVE_NOT_RECRUITING

753 participants

TB-CAPT MTB/XDR Study

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-05-14
Completion:: 2024-12-30

Conditions

Tuberculosis
Resistance Bacterial
Diagnoses Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04564378 | COMPLETED

43 participants

Association Between Fuchs' Endothelial Corneal Dystrophy Severity and Estrogen Exposure

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2018-01-17
Completion:: 2023-04-27

Conditions

Fuchs Dystrophy

Interventions

OTHER

No Results Yet

NCT04563533 | COMPLETED | PHASE1/PHASE2

580 participants

Clinical Trial of Quadrivalent Recombinant Norovirus Vaccine (Pichia Pastoris)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-08-05
Completion:: 2024-09-29

Conditions

Acute Gastroenteritis

Interventions

BIOLOGICAL

No Results Yet

NCT04521621 | TERMINATED | PHASE1/PHASE2

76 participants

A Study of Gebasaxturev (V937) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (V937-013)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-10-28
Completion:: 2023-07-25

Conditions

Neoplasm Metastasis

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04482595 | ACTIVE_NOT_RECRUITING | PHASE2

50 participants

BIO 300 Oral Suspension in Previously Hospitalized Long COVID Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-11-11
Completion:: 2024-07-31

Conditions

COVID-19
Long COVID
Pulmonary Fibrosis
Post-acute Respiratory Complications of COVID-19

Interventions

DRUG

No Results Yet

NCT04481230 | COMPLETED | EARLY_PHASE1

6 participants

Assessment of 99mTc-NTP 15-5 Uptake on Cartilage, a New Proteoglycan Tracer

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-11-12
Completion:: 2022-07-28

Conditions

Osteoarthritis, Knee
Breast Cancer

Interventions

DRUG

No Results Yet

NCT04480671 | COMPLETED | NA

94 participants

Impact of Level III Support Procedure on Enlarged Genital Hiatus After Minimally Invasive Sacrocolpopexy

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-08-26
Completion:: 2023-02-02

Conditions

Pelvic Organ Prolapse

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04471233 | COMPLETED | NA

250 participants

Influence of Patient Sex on Pain Control and Multimodal Analgesia in Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-12-09
Completion:: 2023-06-20

Conditions

Knee Osteoarthritis
Pain, Postoperative

Interventions

OTHER

No Results Yet

NCT04416737 | COMPLETED | PHASE1

16 participants

Evaluating the Benefits of Physiologic Insulin Delivery

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-11-01
Completion:: 2023-06-02

Conditions

Type 1 Diabetes

Interventions

DRUG

Results Available

NCT04360174 | COMPLETED | PHASE1

19 participants

CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2018-04-25
Completion:: 2021-05-24

Conditions

Ocular Hypertension
Open Angle Glaucoma

Interventions

DRUG

Results Available

NCT04325698 | TERMINATED | PHASE3

8 participants

A BRIDGING STUDY OF PF-06439535 (CN) PLUS PACLITAXEL-CARBOPLATIN VERSUS BEVACIZUMAB PLUS PACLITAXEL-CARBOPLATIN IN NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-06-11
Completion:: 2021-05-10

Conditions

Advanced Non-squamous NSCLC

Interventions

DRUG

Results Available

NCT04265599 | RECRUITING

200 participants

Exploring Pathogenesis and Treatment of Hypercalcemia Caused by Intramuscular Injection of Paraffinoil

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-04-30
Completion:: 2027-01-31

Conditions

Hypercalcemia
Renal Injury
Paraffinoma

No Results Yet

NCT04258969 | WITHDRAWN | NA

0 participants

Pedaling at a Low-Moderate Intensity During Chemotherapy Administration

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-01-11
Completion:: 2021-10-14

Conditions

Colorectal Cancer
Exercise, Aerobic
Chemotherapy
Chemotherapeutic Toxicity

Interventions

BEHAVIORAL

No Results Yet

NCT04238143 | RECRUITING | NA

100 participants

Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-01-10
Completion:: 2026-09-30

Conditions

Osteoarthritis
Osteo Arthritis Knee
Osteo Arthritis Shoulders
Osteoarthritis of Multiple Joints
Osteoarthritis, Hip
Osteoarthritis - Ankle/Foot

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT04216589 | COMPLETED | PHASE2

51 participants

Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-02-19
Completion:: 2023-03-16

Conditions

HIV Infections
Non-Alcoholic Fatty Liver Disease

Interventions

DRUG

Results Available

NCT04202913 | COMPLETED | NA

867 participants

Building Resilience for Healthy Kids

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-01-12
Completion:: 2021-05-31

Conditions

Mental Health Wellness 1

Interventions

BEHAVIORAL

No Results Yet

NCT04194320 | COMPLETED | NA

45 participants

Dexamethasone Versus Nalbuphine as Adjuvants in Brachial Plexus Block

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-12-01
Completion:: 2020-05-05

Conditions

Anesthesia

Interventions

PROCEDURE

No Results Yet

NCT04144036 | COMPLETED | PHASE1

12 participants

Neihulizumab for Standard-Risk Acute Graft Versus Host Disease (GVHD)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-12-14
Completion:: 2023-04-20

Conditions

Graft-versus-host Disease

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04114357 | COMPLETED | PHASE1

12 participants

Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-06-22
Completion:: 2023-06-09

Conditions

Type 1 Diabetes

Interventions

DRUG

Results Available

NCT04086212 | WITHDRAWN | PHASE2

0 participants

Ultrafiltration Efficacy of a PD Solution Containing Icodextrin-Xylitol-Carnitine

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-10-02
Completion:: 2022-12-31

Conditions

End Stage Renal Disease (ESRD)

Interventions

DRUG

No Results Yet

NCT04076423 | COMPLETED | PHASE4

141 participants

A Phase IV Study to Assess the Impact of the Change of Antiretroviral Treatment From Dual Therapy to Triple Therapy on Inflammation in Patients With HIV Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-10-10
Completion:: 2023-06-15

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT04066296 | RECRUITING | PHASE2

100 participants

Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-09-08
Completion:: 2024-12-31

Conditions

Lumbar Spinal Stenosis

Interventions

DRUG

No Results Yet

NCT04042922 | ACTIVE_NOT_RECRUITING | NA

80 participants

High Frequency Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-04-19
Completion:: 2026-04-30

Conditions

Alzheimer Disease

Interventions

DEVICE

No Results Yet

NCT04021121 | COMPLETED | PHASE2

40 participants

Adjunctive Linezolid for the Treatment of Tuberculous Meningitis

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-05-05
Completion:: 2023-07-05

Conditions

Tuberculosis, Meningeal

Interventions

DRUG

Results Available

NCT04017832 | COMPLETED | PHASE3

1441 participants

A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-07-29
Completion:: 2021-10-27

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

Results Available

NCT04010526 | RECRUITING | PHASE2

84 participants

Evaluation of Local Co-administration of Autologous ADIpose Derived Stromal Vascular Fraction With Microfat for Refractory Perianal CROHN's Fistulas.

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-02-19
Completion:: 2028-07-31

Conditions

Crohn Disease

Interventions

COMBINATION_PRODUCT
OTHER

No Results Yet

NCT03991013 | COMPLETED | PHASE2

192 participants

Tenofovir-lamivudine-dolutegravir Combination as Second-line ART: a Randomised Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-08-08
Completion:: 2022-04-26

Conditions

HIV Infections

Interventions

DRUG

Results Available

NCT03981900 | COMPLETED

314 participants

IDentification of Factors Predictive of Tofacitinib's Survival in Patient With Rheumatoid Arthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-01-04
Completion:: 2023-02-06

Conditions

Arthritis, Rheumatoid

Interventions

DRUG

Results Available

NCT03909750 | SUSPENDED | PHASE1

50 participants

Use of Autologous Stem/Stromal Cells In Chronic Lung Disorders: Obstructive (COPD) & Restrictive (RLD)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-04-10
Completion:: 2025-09-30

Conditions

COPD
Respiratory Insufficiency

Interventions

PROCEDURE

No Results Yet

NCT03875092 | COMPLETED | PHASE3

125 participants

A Study of Carboplatin-Paclitaxel/Nab-Paclitaxel Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With First Line Metastatic Squamous Non-small Cell Lung Cancer (MK-3475-407/KEYNOTE-407)-China Extension Study

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2017-04-21
Completion:: 2020-09-30

Conditions

Non-small Cell Lung Cancer

Interventions

BIOLOGICAL
DRUG

Results Available

NCT03863704 | COMPLETED | NA

30 participants

Transcutaneous VNS to Treat Pediatric IBD

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-02-14
Completion:: 2022-12-31

Conditions

Crohn Disease
Ulcerative Colitis

Interventions

DEVICE

No Results Yet