Clinical Trials Updated in 2024

NCT05155293 | COMPLETED | PHASE3

413 participants

Clinical Study to Compare Efficacy and Safety of AVT06 and EU-Eylea (ALVOEYE)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2022-06-28
Completion:: 2023-11-17

Conditions

Neovascular (Wet) AMD

Interventions

DRUG

No Results Yet

NCT05145231 | COMPLETED

83 participants

valıdıty and relıabılıty of the turkısh versıon of the functıonal mobılıty Scale ın ındıvıduals wıth Cerebral Palsy

Study Type:: OBSERVATIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-09-15
Completion:: 2022-04-30

Conditions

Cerebral Palsy

Interventions

OTHER

No Results Yet

NCT05118516 | COMPLETED | PHASE1

8 participants

Safety, Tolerability, and Pharmacokinetics of ASC43F, a Fixed Dose Combination Tablet in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-11-01
Completion:: 2021-12-07

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT05118360 | WITHDRAWN | PHASE2

0 participants

Study to Evaluate the Safety, Tolerability, and Efficacy of ASC41 in Adults With NASH

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2023-12-01
Completion:: 2024-11-10

Conditions

Nonalcoholic Steatohepatitis (NASH)

Interventions

DRUG

No Results Yet

NCT05077267 | COMPLETED | PHASE2

197 participants

ABNCoV2 Vaccine in SARS-CoV-2 (COVID-19) Seronegative and Seropositive Adult Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-08-19
Completion:: 2022-02-02

Conditions

COVID-19 Disease

Interventions

BIOLOGICAL

Results Available

NCT05015374 | COMPLETED | NA

46 participants

Effect of Astaxanthin on the Patients With Alzheimer Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2018-11-14
Completion:: 2024-06-01

Conditions

To Evaluate the Possible Benefit of Astaxanthin on Alzheimer Disease

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04964674 | TERMINATED | NA

122 participants

Psychometric Testing and Cue Utilization During Cued Visual Search

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-04-12
Completion:: 2022-08-27

Conditions

Healthy

Interventions

BEHAVIORAL

No Results Yet

NCT04944316 | COMPLETED | NA

35 participants

Effect of a Dietary Intervention on Insulin Requirements in Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2022-01-19
Completion:: 2022-11-09

Conditions

Diabetes Mellitus, Type 1

Interventions

BEHAVIORAL

No Results Yet

NCT04889092 | COMPLETED | NA

5 participants

Blood Flow Restriction Exercise for Those With SCI

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-07-01
Completion:: 2024-08-31

Conditions

Spinal Cord Injury

Interventions

OTHER

No Results Yet

NCT04845646 | COMPLETED | PHASE1

24 participants

DDI Study of ASC41 in HV and the PK, Safety and Tolerability in Subjects With NAFLD.

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-03-16
Completion:: 2021-06-10

Conditions

Healthy
NAFLD

Interventions

DRUG

No Results Yet

NCT04821752 | SUSPENDED | NA

20 participants

Environmental Toxicants Avoidance Study

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2022-05-01
Completion:: 2025-09-01

Conditions

Pollution; Exposure
Glucose Intolerance
Glycemic Control

Interventions

BEHAVIORAL

No Results Yet

NCT04819360 | TERMINATED | PHASE4

1 participants

Botulinum Toxin a Vs Anticholinergic Treatment of Neurogenic Overactive Bladder in Patients with Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-06-01
Completion:: 2022-03-09

Conditions

Urinary Bladder, Neurogenic
Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT04798586 | COMPLETED | PHASE1

4 participants

MAGNETISMM-2: Study of Elranatamab (PF-06863135) in Japanese Participants With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-03-22
Completion:: 2022-05-27

Conditions

Relapsed or Refractory Multiple Myeloma

Interventions

DRUG

Results Available

NCT04776954 | TERMINATED | NA

15 participants

Warming Blanket Comparison Study

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-09-27
Completion:: 2022-11-17

Conditions

Surgery
Temperature Change, Body

Interventions

DEVICE

Results Available

NCT04776746 | TERMINATED | PHASE3

77 participants

Open-Label Extension Study of Trofinetide for Rett Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-11-08
Completion:: 2023-06-30

Conditions

Rett Syndrome

Interventions

DRUG

Results Available

NCT04763278 | COMPLETED | NA

7 participants

Validation of User Needs of the Point Digit With Partial Hand Amputees

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-01-07
Completion:: 2022-03-30

Conditions

Amputation; Traumatic, Hand

Interventions

DEVICE

Results Available

NCT04714281 | COMPLETED | NA

82 participants

Comparison of Clinical Performance and Hemocompatibility of Dialyzers Applied During Post-dilution Online Hemodiafiltration

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-02-03
Completion:: 2023-05-05

Conditions

Renal Failure
End Stage Renal Disease

Interventions

DEVICE

No Results Yet

NCT04692025 | COMPLETED | PHASE1

12 participants

Study to Evaluate the Effect of Food on the Pharmacokinetics of ASC41 in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-12-27
Completion:: 2021-01-14

Conditions

Healthy
NAFLD
Hyperlipidemia

Interventions

DRUG

No Results Yet

NCT04686994 | COMPLETED | PHASE1

20 participants

Study to Evaluate the Safety and Efficacy of ASC41 in Overweight and Obese Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-12-22
Completion:: 2021-01-19

Conditions

Overweight and Obesity
NAFLD
Hyperlipidemia

Interventions

DRUG

No Results Yet

NCT04679129 | COMPLETED | PHASE1

64 participants

Study to Evaluate Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of ASC42 in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-11-30
Completion:: 2021-05-03

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT04638790 | RECRUITING | PHASE3

300 participants

First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-02-01
Completion:: 2026-12-31

Conditions

Hodgkin Lymphoma, Adult

Interventions

DRUG

No Results Yet

NCT04614584 | COMPLETED | PHASE1

15 participants

Mirtazapine and Methamphetamine Drug-drug Interaction Study

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-05-03
Completion:: 2024-05-31

Conditions

Methamphetamine Use Disorder
Drug Interaction
Cardiovascular Abnormalities

Interventions

DRUG

No Results Yet

NCT04589065 | SUSPENDED | NA

10 participants

SCD for CRS in Congestive Heart Failure (CHF) (No Left Ventricular Assist Device)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2025-09-30
Completion:: 2027-12-31

Conditions

Heart Failure
Chronic Systolic Heart Failure
Renal Failure
Cardiorenal Syndrome

Interventions

DEVICE

No Results Yet

NCT04508803 | COMPLETED | PHASE2

37 participants

Combination of HX008 And Niraparib in GErm-line-mutAted Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-09-14
Completion:: 2022-08-20

Conditions

Treatment Efficacy

Interventions

DRUG

No Results Yet

NCT04437888 | COMPLETED | EARLY_PHASE1

200 participants

Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-09-14
Completion:: 2024-04-05

Conditions

Pain, Postoperative
Arthroplasty Complications

Interventions

DRUG

No Results Yet

NCT04431635 | TERMINATED | PHASE1

6 participants

Dose De-escalation Study of the PI3k Alpha/Delta Inhibitor, Copanlisib Given in Combination With the Immunotherapeutic Agents, Nivolumab and Rituximab in Patients With Relapsed/Refractory Indolent Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-06-15
Completion:: 2023-11-14

Conditions

Indolent Lymphoma

Interventions

DRUG

No Results Yet

NCT04291508 | COMPLETED | PHASE2

488 participants

Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-10-13
Completion:: 2023-04-27

Conditions

Acute Respiratory Distress Syndrome
Critical Illness
Respiratory Failure
Sepsis

Interventions

DRUG

Results Available

NCT04258280 | RECRUITING | NA

200 participants

Improving Genetic Counseling for BRCA+ Mothers

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-07-01
Completion:: 2025-12-31

Conditions

Breast Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04225065 | TERMINATED | NA

10 participants

Chlorhexidine and/or Betadine Prep in Pediatric Arm Surgery Following Trauma

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-06-17
Completion:: 2023-12-01

Conditions

Arm Fracture
Surgical Site Infection

Interventions

OTHER

No Results Yet

NCT04213209 | COMPLETED

95 participants

Special Drug Use Surveillance for Brentuximab Vedotin Intravenous Infusion "Relapsed or Refractory CD30-positive Peripheral T Cell Lymphoma or Pediatric Hodgkin Lymphoma"

Study Type:: OBSERVATIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-02-14
Completion:: 2023-12-13

Conditions

Peripheral T Cell Lymphoma
Pediatric Hodgkin Lymphoma

Interventions

DRUG

Results Available

NCT04211766 | COMPLETED | NA

38 participants

Fiber and Fish Oil Supplements for the Prevention of Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-01-05
Completion:: 2022-08-16

Conditions

Healthy Subject

Interventions

DIETARY_SUPPLEMENT
OTHER

Results Available

NCT04206163 | COMPLETED | NA

78 participants

Somatostatin Receptor Imaging in Acute Myocarditis and Cardiac Sarcoidosis

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-01-20
Completion:: 2024-06-24

Conditions

Acute Myocarditis
Cardiac Sarcoidosis

Interventions

DIAGNOSTIC_TEST
BIOLOGICAL

No Results Yet

NCT04147819 | COMPLETED | PHASE1

14 participants

A First in Human Study of BAY2701439 to Look at Safety, How the Body Absorbs, Distributes and Excretes the Drug, and How Well the Drug Works in Participants With Advanced Cancer Expressing the HER2 Protein

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-07-02
Completion:: 2023-08-21

Conditions

Cancers With HER2 Expression

Interventions

DRUG

No Results Yet

NCT04117945 | ACTIVE_NOT_RECRUITING | PHASE2

22 participants

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2020-03-03
Completion:: 2023-09-05

Conditions

BRAF V600E Negative
KRAS Gene Mutation Negative
Locally Advanced Unresectable Colorectal Adenocarcinoma
Metastatic Colorectal Adenocarcinoma
NRAS Gene Mutation Negative
Stage III Colorectal Cancer AJCC v8
Stage IIIA Colorectal Cancer AJCC v8
Stage IIIB Colorectal Cancer AJCC v8
Stage IIIC Colorectal Cancer AJCC v8
Stage IV Colorectal Cancer AJCC v8
Stage IVA Colorectal Cancer AJCC v8
Stage IVB Colorectal Cancer AJCC v8
Stage IVC Colorectal Cancer AJCC v8

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04079933 | COMPLETED | NA

154 participants

A Study to Evaluate Changes in Smokers Using An Oral Tobacco-Derived Nicotine Product

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2013-08-27
Completion:: 2013-11-26

Conditions

Tobacco Use

Interventions

OTHER

Results Available

NCT03998319 | RECRUITING | PHASE3

445 participants

A Study of Low-dose Intracoronary Thrombolytic Therapy in STEMI (Heart Attack) Patients.

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2021-10-14
Completion:: 2024-12-31

Conditions

STEMI
Elevated IMR (>32)

Interventions

DRUG
OTHER

No Results Yet

NCT03920683 | COMPLETED

707 participants

Toe-brachial Index and Coronary Calcification in Type 1 and 2 Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2024-09-27
Start Date:: 2019-07-08
Completion:: 2022-04-14

Conditions

Coronary Artery Calcification

Interventions

OTHER

No Results Yet

NCT03891329 | COMPLETED | NA

130 participants

Master Study of the Acticor/Rivacor ICDs/CRT-Ds and the Plexa ProMRI S DX Lead

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2019-04-30
Completion:: 2020-12-21

Conditions

Heart Failure
Tachyarrhythmia

Interventions

DEVICE

Results Available

NCT03864042 | COMPLETED | PHASE1

56 participants

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2018-01-02
Completion:: 2022-07-11

Conditions

Advanced Solid Tumors
Metastatic Melanoma

Interventions

DRUG

Results Available

NCT03823651 | COMPLETED | NA

29 participants

A Research Program Targeting Pre- and Peri-transplant Optimization Program (R-PPOP)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-09-27
Start Date:: 2019-05-06
Completion:: 2022-10-27

Conditions

Hematologic Malignancy

Interventions

BEHAVIORAL

Results Available