Clinical Trials

Showing trials with last updates posted in 2023.

NCT03592641 | TERMINATED | PHASE2
5 participants

Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2023-10-17
Start Date:
2019-07-25
Completion:
2021-07-31
Conditions
  • Colorectal Carcinoma
  • Metastatic Colon Adenocarcinoma
  • Metastatic Rectal Adenocarcinoma
  • Stage III Colon Cancer AJCC v8
  • Stage III Rectal Cancer AJCC v8
  • Stage IIIA Colon Cancer AJCC v8
  • Stage IIIA Rectal Cancer AJCC v8
  • Stage IIIB Colon Cancer AJCC v8
  • Stage IIIB Rectal Cancer AJCC v8
  • Stage IIIC Colon Cancer AJCC v8
  • Stage IIIC Rectal Cancer AJCC v8
  • Stage IV Colon Cancer AJCC v8
  • Stage IV Rectal Cancer AJCC v8
  • Stage IVA Colon Cancer AJCC v8
  • Stage IVA Rectal Cancer AJCC v8
  • Stage IVB Colon Cancer AJCC v8
  • Stage IVB Rectal Cancer AJCC v8
  • Stage IVC Colon Cancer AJCC v8
  • Stage IVC Rectal Cancer AJCC v8
  • Unresectable Colon Adenocarcinoma
  • Unresectable Rectal Adenocarcinoma
Interventions
  • DRUG
NCT03366103 | TERMINATED | PHASE1/PHASE2
15 participants

Navitoclax and Vistusertib in Treating Patients With Relapsed Small Cell Lung Cancer and Other Solid Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2023-10-17
Start Date:
2018-03-20
Completion:
2021-07-28
Conditions
  • Metastatic Malignant Solid Neoplasm
  • Recurrent Lung Small Cell Carcinoma
  • Recurrent Malignant Solid Neoplasm
  • Refractory Malignant Solid Neoplasm
  • Stage III Lung Small Cell Carcinoma, by American Joint Committee on Cancer (AJCC) v7
  • Stage IIIA Lung Small Cell Carcinoma AJCC v7
  • Stage IIIB Lung Small Cell Carcinoma AJCC v7
  • Stage IV Lung Small Cell Carcinoma AJCC v7
  • Unresectable Solid Neoplasm
Interventions
  • BIOLOGICAL
  • DRUG
NCT03208010 | COMPLETED | NA
300 participants

Diabetes Prevention for Mexican Americans

Study Type:
INTERVENTIONAL
Last Updated:
2023-10-17
Start Date:
2017-04-01
Completion:
2023-07-31
Conditions
  • Prediabetic State
  • Overweight and Obesity
Interventions
  • BEHAVIORAL
  • OTHER
No Results Yet
NCT02780804 | COMPLETED | PHASE1
21 participants

Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2023-10-17
Start Date:
2017-01-06
Completion:
2021-06-30
Conditions
  • Brain Stem Neoplasm
  • Pineal Region Neoplasm
  • Recurrent Lymphoma
  • Recurrent Malignant Solid Neoplasm
  • Recurrent Primary Central Nervous System Neoplasm
  • Recurrent Visual Pathway Glioma
  • Refractory Lymphoma
  • Refractory Malignant Solid Neoplasm
  • Refractory Primary Central Nervous System Neoplasm
  • Refractory Visual Pathway Glioma
Interventions
  • DRUG
  • OTHER
NCT02500797 | COMPLETED | PHASE2
164 participants

Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery

Study Type:
INTERVENTIONAL
Last Updated:
2023-10-17
Start Date:
2015-08-13
Completion:
2019-04-01
Conditions
  • Locally Advanced Bone Sarcoma
  • Locally Advanced Dedifferentiated Liposarcoma
  • Locally Advanced Gastrointestinal Stromal Tumor
  • Locally Advanced Soft Tissue Sarcoma
  • Metastatic Bone Sarcoma
  • Metastatic Liposarcoma
  • Metastatic Soft Tissue Sarcoma
  • Metastatic Undifferentiated Pleomorphic Sarcoma
  • Metastatic Unresectable Sarcoma
  • Pleomorphic Liposarcoma
  • Stage III Bone Sarcoma AJCC v7
  • Stage III Soft Tissue Sarcoma AJCC v7
  • Stage IV Bone Sarcoma AJCC v7
  • Stage IV Soft Tissue Sarcoma AJCC v7
  • Stage IVA Bone Sarcoma AJCC v7
  • Stage IVB Bone Sarcoma AJCC v7
  • Unresectable Bone Sarcoma
  • Unresectable Dedifferentiated Liposarcoma
  • Unresectable Liposarcoma
  • Unresectable Malignant Gastrointestinal Stromal Tumor
  • Unresectable Soft Tissue Sarcoma
Interventions
  • BIOLOGICAL
  • OTHER
NCT02304458 | COMPLETED | PHASE1/PHASE2
140 participants

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

Study Type:
INTERVENTIONAL
Last Updated:
2023-10-17
Start Date:
2015-03-30
Completion:
2021-09-30
Conditions
  • Metastatic Melanoma
  • Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
  • Recurrent Hodgkin Lymphoma
  • Recurrent Malignant Solid Neoplasm
  • Recurrent Melanoma
  • Recurrent Neuroblastoma
  • Recurrent Non-Hodgkin Lymphoma
  • Recurrent Osteosarcoma
  • Recurrent Rhabdomyosarcoma
  • Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
  • Refractory Hodgkin Lymphoma
  • Refractory Malignant Solid Neoplasm
  • Refractory Melanoma
  • Refractory Neuroblastoma
  • Refractory Non-Hodgkin Lymphoma
  • Refractory Osteosarcoma
  • Refractory Rhabdomyosarcoma
  • Stage III Cutaneous Melanoma AJCC v7
  • Stage IIIA Cutaneous Melanoma AJCC v7
  • Stage IIIB Cutaneous Melanoma AJCC v7
  • Stage IIIC Cutaneous Melanoma AJCC v7
  • Stage IV Cutaneous Melanoma AJCC v6 and v7
  • Unresectable Melanoma
Interventions
  • BIOLOGICAL
  • OTHER
NCT01956058 | COMPLETED | PHASE2
30 participants

Brachytherapy for Recurrent Prostate Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2023-10-17
Start Date:
2013-03-26
Completion:
2013-03-26
Conditions
  • Recurrent Prostate Cancer
  • Brachytherapy Remedial
Interventions
  • RADIATION
No Results Yet
NCT01622868 | COMPLETED | PHASE2
143 participants

Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2023-10-17
Start Date:
2012-12-06
Completion:
2019-12-30
Conditions
  • HER2-Positive Breast Carcinoma
  • Invasive Breast Carcinoma
  • Metastatic Malignant Neoplasm in the Brain
  • Recurrent Breast Carcinoma
  • Stage IV Breast Cancer AJCC v6 and v7
Interventions
  • OTHER
  • DRUG
  • RADIATION
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