Clinical Trials Updated in 2022

NCT05024812 | UNKNOWN | PHASE1/PHASE2

64 participants

Fruquintinib Combined With Toripalimab and SOX Regimen in the First-line Treatment of Advanced Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2022-06-01
Completion:: 2023-08-31

Conditions

Metastatic Gastric Cancer

Interventions

DRUG

No Results Yet

NCT05016869 | UNKNOWN | PHASE1/PHASE2

48 participants

Fruquintinib Plus Capecitabine as Maintenance Treatment of RAS / BRAF Wild-type Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2022-04-12
Completion:: 2023-02-28

Conditions

Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT05004831 | UNKNOWN | PHASE2

54 participants

Fruquintinib Combined With TAS-102 in the Treatment of Patients With Advanced Metastatic CRC

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2022-03-11
Completion:: 2023-09-30

Conditions

Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT05001698 | COMPLETED | PHASE1

15 participants

Anifrolumab PK Study for Systemic Lupus Erythematosus (SLE)

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-07-27
Completion:: 2022-06-02

Conditions

Systemic Lupus Erythematosus

Interventions

BIOLOGICAL

No Results Yet

NCT05000333 | COMPLETED

50 participants

Consequences of Covid-19 on the Psychological and Physical Health of the Nursing Staff and on Their Professional Activity.

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-09-03
Completion:: 2022-03-15

Conditions

Work-related Illness

Interventions

OTHER

No Results Yet

NCT04974281 | UNKNOWN | EARLY_PHASE1

50 participants

PD-1 Antibody and Lenvatinib Plus TACE on Downstaging BCLC B/C HCC

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-01-01
Completion:: 2022-12-31

Conditions

Hepatocellular Carcinoma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT04949867 | COMPLETED | PHASE4

11 participants

Dual-Hormone Closed-Loop Glucose Control in Adolescents With Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-05-20
Completion:: 2022-04-26

Conditions

Type 1 Diabetes

Interventions

DRUG
DEVICE

No Results Yet

NCT04935866 | UNKNOWN

286 participants

Optimal Brain Oxygenation in Neurologic Intensive Care Unit : The NeurO2 Study

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-05-07
Completion:: 2024-07-31

Conditions

Traumatic Brain Injury
Subarachnoid Hemorrhage
Brain Injuries
Near-Infrared Spectroscopy
Intensive Care Neurological Disorder
Anemia

Interventions

OTHER

No Results Yet

NCT04918797 | COMPLETED | PHASE2/PHASE3

525 participants

COVAXIN in a Pediatric Cohort

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-05-26
Completion:: 2021-08-15

Conditions

SARS-CoV2 Infection

Interventions

BIOLOGICAL

No Results Yet

NCT04897750 | COMPLETED | PHASE2

25 participants

Pharmacokinetic Study of Intranasal CT001 in Children 1-17 Years of Age Undergoing Elective Surgical Procedures

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-08-19
Completion:: 2022-05-16

Conditions

Analgesia

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT04893876 | NOT_YET_RECRUITING

1200 participants

The OPERa Study: Evaluating QoL After Rectal Cancer Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2023-01-01
Completion:: 2028-09-30

Conditions

Rectal Cancer
Quality of Life
Bowel Dysfunction
Sexual Dysfunction
Urinary Dysfunction
Emotional Distress
Surgery

No Results Yet

NCT04866108 | UNKNOWN | PHASE2

49 participants

A Phase II Study of Fruquintinib Combined With Capecitabine as First-line Treatment for Advanced Metastatic Colorectal Cancer Unsuitable for Intravenous Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-12-08
Completion:: 2024-06-30

Conditions

Unresectable Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT04856761 | UNKNOWN

160 participants

A Study of Capecitabine Versus S-1 as Adjuvant Therapy in Patients With Biliary Tract Carcinoma After Surgical Resection

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-11-01
Completion:: 2022-12-30

Conditions

Biliary Tract Neoplasms
Recurrence
Cholangiocarcinoma
Gall Bladder Cancer

Interventions

DRUG

No Results Yet

NCT04834401 | COMPLETED

45 participants

Effect of Disease Modifying Therapy on Antibody Response to COVID19 Vaccination in Multiple Sclerosis

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-03-22
Completion:: 2022-05-17

Conditions

Multiple Sclerosis
Covid19

No Results Yet

NCT04819152 | UNKNOWN

8000 participants

Effectiveness of Tobacco Cessation Interventions in Sweden

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-04-09
Completion:: 2022-12-31

Conditions

Tobacco Use
Smoking
Cigarette Use, Electronic

Interventions

BEHAVIORAL

No Results Yet

NCT04782804 | UNKNOWN | PHASE1/PHASE2

30 participants

Adjuvant PD-1 Antibody in Combination With Capecitabine for Patients With ICC at High-Risk of Postoperative Recurrence

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-01-01
Completion:: 2023-12-30

Conditions

Cholangiocarcinoma, Intrahepatic

Interventions

DRUG

No Results Yet

NCT04751682 | COMPLETED | PHASE1

175 participants

Safety and Immunogenicity of an Intranasal SARS-CoV-2 Vaccine (BBV154) for COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-03-01
Completion:: 2021-06-25

Conditions

SARS-CoV Infection

Interventions

BIOLOGICAL

No Results Yet

NCT04684251 | WITHDRAWN | NA

0 participants

ARTerial EMbolization for haemorrhoIdal Disease (ART.EM.I. Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-11-25
Completion:: 2022-05-24

Conditions

Haemorrhoidal Bleeding

Interventions

PROCEDURE

No Results Yet

NCT04658901 | COMPLETED | NA

188 participants

ACOART RF CLOSURE:Radiofrequency for Varicose Veins of Lower Extremity in China

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2021-05-18
Completion:: 2022-01-01

Conditions

Varicose Veins of Lower Limb

Interventions

DEVICE

No Results Yet

NCT04640922 | COMPLETED | NA

152 participants

Clinical Performance and Safety of the Gedea Pessary in Adult Women With Bacterial Vaginosis

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-01-27
Completion:: 2022-01-31

Conditions

Bacterial Vaginosis

Interventions

DEVICE

No Results Yet

NCT04562298 | TERMINATED | PHASE1

15 participants

A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of LCAR-M23, a CAR-T Cell Therapy Targeting MSLN in Patients With Relapsed and Refractory Epithelial Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-10-21
Completion:: 2022-06-07

Conditions

Epithelial Ovarian Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT04562155 | COMPLETED | PHASE2

310 participants

Clinical Study to Evaluate the Efficacy and Safety of Three Different Doses of BAY1817080 Compared to Placebo in Patients With Chronic Cough

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-10-02
Completion:: 2021-06-22

Conditions

Refractory and/or Unexplained Chronic Cough

Interventions

DRUG

Results Available

NCT04555564 | WITHDRAWN | NA

0 participants

Tc99m Macroaggregated Albumin Bronchial Artery Study

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2022-08-01
Completion:: 2024-12-31

Conditions

Hemoptysis
Malignant Neoplasm
Lung Cancer

Interventions

PROCEDURE

No Results Yet

NCT04538222 | COMPLETED

86 participants

Workplace Physical Activity Intervention

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-09-07
Completion:: 2020-11-13

Conditions

Health Promotion

Interventions

OTHER

No Results Yet

NCT04478045 | COMPLETED

278 participants

The Application of Point-of-care Ultrasonography in Differential Diagnosis of Shock in Emergency and Critical Care

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-08-01
Completion:: 2022-07-31

Conditions

Shock
Ultrasonography
Differential Diagnosis
Emergencies
Critical Care

No Results Yet

NCT04471519 | COMPLETED | PHASE1/PHASE2

755 participants

Whole-Virion Inactivated SARS-CoV-2 Vaccine (BBV152) for COVID-19 in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-07-15
Completion:: 2020-07-31

Conditions

COVID-19
SARS-CoV-2 Infection

Interventions

BIOLOGICAL

No Results Yet

NCT04463628 | COMPLETED

746 participants

Impacts of the Covid-19 Epidemic and Associated Lockdown Measures on the Management, Health and Behaviors of Cystic Fibrosis Patients During the 2020 Epidemic

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-05-15
Completion:: 2021-12-30

Conditions

Cystic Fibrosis in Children
Cystic Fibrosis

Interventions

BEHAVIORAL

No Results Yet

NCT04463290 | UNKNOWN

200 participants

Association of Single Nucleotide Polymorphisms (SNPs) in Metalloproteinases (MMPs) Genes With the Risk of Primary Knee Osteoarthritis in Greek Population.

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-07-06
Completion:: 2022-11-28

Conditions

Metalloproteinase SNPs -1575 G/A MMP-2, 836 A/G MMP-9 and -77 A/G MMP-13 and Risk for Developing Knee Osteoarthritis in Greek Population

Interventions

OTHER

No Results Yet

NCT04443426 | UNKNOWN | PHASE2

8 participants

Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Chronic Heart Failure: Cardiovascular Effects

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2019-04-25
Completion:: 2022-11-01

Conditions

Heart Failure
Ketosis
Ketonemia

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04397107 | COMPLETED | NA

46 participants

The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 on Children With Rheumatic Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-08-15
Completion:: 2022-05-31

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT04387942 | COMPLETED | NA

59 participants

The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-schönlein Purpura

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-06-14
Completion:: 2022-05-31

Conditions

Purpura, Schoenlein-Henoch

Interventions

DRUG

No Results Yet

NCT04372329 | COMPLETED | NA

59 participants

Promoting the Use of CPAP Therapy Among OSA Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-07-01
Completion:: 2021-09-30

Conditions

Obstructive Sleep Apnea

Interventions

BEHAVIORAL

No Results Yet

NCT04360135 | WITHDRAWN | PHASE2/PHASE3

0 participants

Preemptive Acetaminophen for Postoperative Pain Control Following Minimally Invasive Hysterectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-05-06
Completion:: 2021-03-08

Conditions

Post Operative Pain

Interventions

DRUG

No Results Yet

NCT04316923 | UNKNOWN

80 participants

Analysis of Cardiac Biomarkers, ECG and CPET Results in Children With Cardiomyopathies

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-03-01
Completion:: 2024-03-31

Conditions

Cardiomyopathies

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04293302 | COMPLETED

350 participants

Early Postnatal Management of Gestational Brain Sonographic Malformations.

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-03-01
Completion:: 2021-12-31

Conditions

Brain Abnormalities

Interventions

OTHER

No Results Yet

NCT04217811 | COMPLETED

237 participants

Late Neutropenia in VLBW Preterm Babies

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-01-01
Completion:: 2021-12-31

Conditions

Neutropenia

Interventions

OTHER

No Results Yet

NCT04208971 | COMPLETED

1225 participants

Batch Enrollment for AI-Guided Intervention to Lower Neurologic Events in Unrecognized AF

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-11-02
Completion:: 2022-01-27

Conditions

Atrial Fibrillation

Interventions

OTHER

No Results Yet

NCT04187690 | UNKNOWN | NA

312 participants

Jin-shui Huan-xian Granule in the Treatment of IPF

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2020-09-01
Completion:: 2023-05-31

Conditions

Idiopathic Pulmonary Fibrosis

Interventions

DRUG

No Results Yet

NCT04122833 | UNKNOWN

80 participants

Impact of Concomitant Genetic Alterations in EGFR Mutated Adenocarcinoma by NGS Analysis: A Multicenter Study

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-18
Start Date:: 2019-09-30
Completion:: 2023-09-30

Conditions

Adenocarcinoma of Lung
EGFR Activating Mutation

Interventions

OTHER

No Results Yet

NCT04099927 | COMPLETED | PHASE1

12 participants

A Study of SHR4010 in Patients With Hemodialysis

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-18
Start Date:: 2019-07-28
Completion:: 2020-04-20

Conditions

Pruritus

Interventions

DRUG

No Results Yet