Clinical Trials Updated in 2022

NCT05170256 | UNKNOWN | PHASE2

24 participants

Trastuzumab and Standard Treatment With Chemo- and Immunotherapy as First Line Treatment for HER2 Positive Esophageal Squamous Cell Carcinoma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2022-02-04
Completion:: 2025-01-31

Conditions

Esophageal Squamous Cell Carcinoma
HER-2 Protein Overexpression
HER-2 Gene Amplification

Interventions

DRUG

No Results Yet

NCT05033145 | COMPLETED | PHASE3

312 participants

Study on Safety and Clinical Efficacy of AZVUDINE in Initial Stage COVID-19 Patients (SARS-CoV-2 Infected)

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2022-01-15
Completion:: 2022-07-27

Conditions

COVID-19

Interventions

DRUG

No Results Yet

NCT05030688 | WITHDRAWN | NA

0 participants

Fascia Iliaca Compartment Block and PENG Block for Hip Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-09-23
Completion:: 2022-06-20

Conditions

Hip Fractures
Hip Injuries
Hip Arthropathy

Interventions

OTHER

No Results Yet

NCT04989465 | COMPLETED | PHASE4

600 participants

A Clinical Trial of 23-valent Pneumococcal Polysaccharide Vaccine

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-09-10
Completion:: 2021-09-13

Conditions

Pneumococcal Infections

Interventions

BIOLOGICAL

No Results Yet

NCT04965740 | COMPLETED

102 participants

Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-06-04
Completion:: 2022-02-04

Conditions

PTSD
Anxiety
Anxiety Disorders
Depression
Depressive Disorder
Psychological
Psychedelic Experiences
Psychedelic Drug Dependence

Interventions

DRUG

No Results Yet

NCT04923594 | COMPLETED | PHASE2

67 participants

Four-week Study of the Safety and Efficacy of NLS-2 (Mazindol Extended Release) in the Treatment of Narcolepsy

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-09-13
Completion:: 2022-06-30

Conditions

Narcolepsy
Excessive Daytime Sleepiness
Cataplexy Narcolepsy

Interventions

DRUG

No Results Yet

NCT04912050 | COMPLETED

33 participants

EXtension of Tablo TrEatmeNt Duration Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-05-25
Completion:: 2022-05-31

Conditions

End Stage Renal Disease (ESRD)
End Stage Renal Disease on Dialysis
Acute Kidney Injury

Interventions

DEVICE

No Results Yet

NCT04912024 | COMPLETED

458 participants

Comparative Outcome Measures of Patients Receiving Acute Renal ThErapy Study

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-05-15
Completion:: 2022-06-15

Conditions

End Stage Kidney Disease
End Stage Renal Disease
Acute Kidney Injury

Interventions

DEVICE

No Results Yet

NCT04863521 | UNKNOWN | NA

150 participants

Evaluation of MHP 3.0 in Two Clinical Settings

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2022-06-20
Completion:: 2023-03-31

Conditions

Telemedicine

Interventions

OTHER

No Results Yet

NCT04852991 | COMPLETED | NA

30 participants

Modified Purandare's Cervicopexy Versus Abdominal Sacral Hysteropexy

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-04-15
Completion:: 2021-04-20

Conditions

Pelvic Organ Prolapse

Interventions

PROCEDURE

No Results Yet

NCT04841213 | COMPLETED | NA

384 participants

Dental Implants Rehabilitation in Patients With Vitamin D3 Imbalance

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-04-10
Completion:: 2022-04-10

Conditions

Tooth Loss
Vitamin D3 Deficiency
Osteomalacia

Interventions

PROCEDURE

No Results Yet

NCT04829721 | COMPLETED | NA

114 participants

Pelvic Floor Disorder Assessment of Knowledge and Symptoms: an Educational Model in Spanish-Speaking Women

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-05-01
Completion:: 2021-12-31

Conditions

Pelvic Organ Prolapse
Urinary Incontinence
Patient Education

Interventions

OTHER

No Results Yet

NCT04710446 | UNKNOWN

200 participants

Clinical Characteristics, Treatments, and Outcomes of MI Patients Presenting With Normal ECG

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2018-01-01
Completion:: 2023-01-01

Conditions

Non-ST Elevated Myocardial Infarction
Electrocardiography

No Results Yet

NCT04668274 | COMPLETED | PHASE1

24 participants

JOTROL PK, Safety, and Food Effect Assessment

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-01-21
Completion:: 2021-02-28

Conditions

Pharmacokinetics
Safety
Food-drug Interaction

Interventions

DRUG

Results Available

NCT04668235 | COMPLETED | PHASE3

180 participants

Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (SARS-CoV-2 Infected)

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2021-04-23
Completion:: 2022-08-10

Conditions

COVID-19

Interventions

DRUG

No Results Yet

NCT04625231 | COMPLETED | NA

60 participants

Shared Decision-Making Tool for Opioid Prescribing After Ambulatory Hand Surgery in Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2018-11-09
Completion:: 2022-05-01

Conditions

Opioid Use
Surgery

Interventions

BEHAVIORAL

No Results Yet

NCT04589910 | COMPLETED | NA

120 participants

Measuring Thickness of the Normal Diaphragm in Children Via Ultrasound.

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-09-01
Completion:: 2021-05-01

Conditions

Mechanical Ventilation Complication
Pediatric ALL
Intensive Care Unit Acquired Weakness

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04514965 | RECRUITING

100 participants

Bezafibrate in Patients With Primary Biliary Cholangitis (PBC)

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-10-01
Completion:: 2026-09-30

Conditions

Primary Biliary Cirrhosis

Interventions

OTHER
DEVICE

No Results Yet

NCT04484415 | UNKNOWN | PHASE3

402 participants

Efficacy and Safety of Cevira® in Patients With Cervical Histologic High-grade Squamous Intraepithelial Lesions (HSIL)

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-11-10
Completion:: 2023-12-31

Conditions

Cervical Intraepithelial Neoplasia Grade 2/3

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT04432805 | TERMINATED | NA

2 participants

Descriptive and Evaluation Study of the Use of Pulmonary Ultrasound in the Initial Management of Pregnant Women in the Context of COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-10-13
Completion:: 2021-01-02

Conditions

Pregnant Women Suspected of COVID-19

Interventions

DEVICE

No Results Yet

NCT04419454 | COMPLETED

10 participants

Retrospective Evaluation of Cellulite of Laxity Treatment Using Body Tite

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-05-05
Completion:: 2022-07-30

Conditions

Cellulite

Interventions

DEVICE

No Results Yet

NCT04411108 | COMPLETED | NA

40 participants

Motion Coaching Technology for Physical Therapy in Low Back Pain.

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-10-20
Completion:: 2021-09-27

Conditions

Low Back Pain

Interventions

OTHER

No Results Yet

NCT04385966 | COMPLETED | PHASE3

48 participants

Diaphragmatic Paralysis Comparison Between Local Anesthetic Volumen Doses After Interscalene Block

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-02-11
Completion:: 2021-10-20

Conditions

Diaphragmatic Paralysis
Brachial Plexus Block

Interventions

PROCEDURE
DRUG

No Results Yet

NCT04383795 | COMPLETED

29 participants

Change of Gut Microbiome in the Treatment of Graves' Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-05-19
Completion:: 2021-12-31

Conditions

Graves' Disease

Interventions

DRUG

No Results Yet

NCT04338984 | COMPLETED | PHASE4

86 participants

Nociception-directed Erector Muscle Spinae Plane Block in Open Heart Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-12-01
Completion:: 2021-04-30

Conditions

Regional Anesthesia
Heart Surgery

Interventions

DRUG

No Results Yet

NCT04324372 | COMPLETED | PHASE1

12 participants

Clinical Study of HEC68498 in Patients With Advanced Refractory Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-02-27
Completion:: 2021-02-26

Conditions

Advanced Refractory Solid Tumors

Interventions

DRUG

No Results Yet

NCT04265846 | UNKNOWN

140 participants

Prospective Clinical Study of Different Intraocular Lens Implantation Designed for the Correction of Presbyopia

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-05-31
Completion:: 2022-05-31

Conditions

Presbyopia
Cataract Senile

Interventions

DEVICE

No Results Yet

NCT04258592 | TERMINATED | PHASE1

6 participants

18F-MFBG PET Imaging of the Norepinephrine Transporter in Neural Crest and Neuroendocrine Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2020-02-07
Completion:: 2022-07-07

Conditions

Neural Crest Tumor
Neuroendocrine Tumors

Interventions

DRUG
DEVICE
OTHER

No Results Yet

NCT04009070 | COMPLETED | NA

70 participants

Effect of Acupuncture on Nausea, Vomiting, Pain, PGE2 and IL 6 in Septorhinoplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-08-15
Completion:: 2020-04-10

Conditions

Pain
Acupuncture

Interventions

DEVICE

No Results Yet

NCT03948958 | COMPLETED | NA

100 participants

PREMO Study: to Investigate Port REMoval Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-06-28
Completion:: 2022-07-08

Conditions

Neoplasms
Cystic Fibrosis

Interventions

OTHER

No Results Yet

NCT03945604 | COMPLETED | PHASE1

32 participants

A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Apatinib and Fluzoparib in Patients With TNBC

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-06-04
Completion:: 2021-02-09

Conditions

Triple Negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT03935113 | COMPLETED | NA

1 participants

Effects of Kinesio Taping for Upper Limb Function of Stroke Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-05-01
Completion:: 2020-07-30

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT03917472 | COMPLETED | PHASE3

517 participants

Efficacy and Safety of Brolucizumab vs Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-07-17
Completion:: 2021-03-24

Conditions

Diabetic Macular Edema

Interventions

DRUG

Results Available

NCT03891173 | TERMINATED | PHASE2

9 participants

A Study of L-DOS47 in Combination With Vinorelbine/Cisplatin in Lung Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-02-19
Completion:: 2020-05-22

Conditions

Lung Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT03844256 | RECRUITING | PHASE1/PHASE2

50 participants

A Study of Mitomycin-c/ Capecitabine ChemoRadiotherapy Combined With Nivolumab Monotherapy or Ipilumimab and Nivolumab, as Bladder Sparing Curative Treatment for Muscle Invasive Bladder Cancer: the CRIMI Study

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-01-07
Completion:: 2024-07-31

Conditions

Urinary Bladder Cancer
Invasive Bladder Cancer

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT03789253 | RECRUITING

300 participants

Identify Genes/Pathways Responsible for Progression From Low Risk to Higher Risk Prostate Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2019-01-02
Completion:: 2030-07-31

Conditions

Prostate Cancer Stage I

No Results Yet

NCT03759041 | TERMINATED | PHASE2

203 participants

A Study to Assess Efficacy and Safety of SER-287 in Adults With Active Mild-to-Moderate Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2018-12-19
Completion:: 2021-05-28

Conditions

Ulcerative Colitis

Interventions

DRUG

Results Available

NCT03663400 | COMPLETED

47 participants

Identify Predictors That Distinguish Between Tofacitinib Responders and Non-responders Based on Genotype and Cellular and Molecular Profiles From Pinch Biopsies, Blood and Stool Samples

Study Type:: OBSERVATIONAL
Last Updated:: 2022-08-12
Start Date:: 2018-12-04
Completion:: 2022-03-24

Conditions

Ulcerative Colitis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03595384 | COMPLETED | NA

41 participants

Soccer-based Adaptation of the Diabetes Prevention Program

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2018-04-29
Completion:: 2018-12-16

Conditions

Diabetes

Interventions

BEHAVIORAL

Results Available

NCT03537118 | COMPLETED | NA

621 participants

Routine Ultrasound Guidance for Vascular Access for Cardiac Procedures

Study Type:: INTERVENTIONAL
Last Updated:: 2022-08-12
Start Date:: 2018-06-20
Completion:: 2022-05-30

Conditions

Myocardial Infarction
Coronary Artery Disease
Myocardial Ischemia

Interventions

PROCEDURE

No Results Yet