Clinical Trials Updated in 2021

NCT04680676 | WITHDRAWN | PHASE2

0 participants

A Study to Test Different Doses of BI 730357 and Find Out Whether They Reduce Symptoms in People With Active Psoriatic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2022-05-02
Completion:: 2023-06-26

Conditions

Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT04674345 | UNKNOWN | PHASE2/PHASE3

346 participants

Sorafenib Maintenance for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3 Negative Acute Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-12-15
Completion:: 2022-12-31

Conditions

Acute Leukemia
Relapse
Hematopoietic Stem Cell Transplantation

Interventions

DRUG

No Results Yet

NCT04648553 | COMPLETED | PHASE1

28 participants

Task-Based Grounding Program

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-12-03
Completion:: 2021-10-01

Conditions

Aggressive
Defiant Disorder, Oppositional
Attention Deficit Hyperactivity Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT04615936 | COMPLETED | NA

45 participants

Nasal Photodisinfection COVID-19 Proof of Concept Study

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-10-13
Completion:: 2021-07-07

Conditions

COVID-19
Corona Virus Infection
SARS-CoV 2

Interventions

OTHER

No Results Yet

NCT04555031 | COMPLETED | NA

10 participants

Evaluation of Surface Refractive Index Shift of Kalifilcon A Lenses Compared to Dailies Total 1, Precision 1 and Biotrue ONEday Lenses

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-09-09
Completion:: 2020-09-16

Conditions

Habitual Soft Contact Lens Use

Interventions

DEVICE

Results Available

NCT04548882 | WITHDRAWN | NA

0 participants

Calypso Knee System Clinical Sub-study, OUS Continued Evaluation

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-09-11
Completion:: 2021-10-12

Conditions

Osteoarthritis, Knee

Interventions

DEVICE

No Results Yet

NCT04544254 | COMPLETED | NA

32 participants

Effectivity of Bilateral Transversus Thoracis Muscle Plane Block After Open Heart Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-10-15
Completion:: 2021-03-15

Conditions

Interleukin-6
Cortisol

Interventions

PROCEDURE

No Results Yet

NCT04517474 | UNKNOWN | NA

300 participants

Comparing the Spanish Version of CANreduce With or Without Psychological Support and Treatment as Usual, Reducing Cannabis Use.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-11-10
Completion:: 2022-11-01

Conditions

Cannabis Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT04489498 | COMPLETED

196 participants

Comparison of Somatometric Characteristics Between Cerebral Palsy and Normal Children, Cross-sectional, Multi Center Study

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-09-27
Completion:: 2021-09-06

Conditions

Cerebral Palsy

No Results Yet

NCT04474587 | SUSPENDED

30 participants

Resting Energy Expenditure in Patients With OHS Treated With Long-term NIV

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-09-01
Completion:: 2022-12-01

Conditions

Obesity-hypoventilation Syndrome
Resting Energy Expenditure
Long-term Non-invasive Ventilation

Interventions

OTHER

No Results Yet

NCT04470713 | COMPLETED

226 participants

Natural History Study for Pediatric Patients With Early Onset of Either GM1 Gangliosidosis, GM2 Gangliosidoses, or Gaucher Disease Type 2

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-07-31
Completion:: 2021-10-30

Conditions

GM1 Gangliosidosis
GM2 Gangliosidosis
Gaucher Disease, Type 2
Tay-Sachs Disease
AB Variant Gangliosidosis GM2
Sandhoff Disease

No Results Yet

NCT04466657 | WITHDRAWN | NA

0 participants

Antioxidant Therapy for COVID-19 Study

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-11-01
Completion:: 2021-02-28

Conditions

Covid-19

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT04454931 | COMPLETED

46 participants

Evaluation of the Effect of Endotracheal Suctioning Applied at Different Head Heights on the Oxygenation of the Brain

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-04-01
Completion:: 2021-09-01

Conditions

Nurse's Role
Endotracheal Aspiration

Interventions

DEVICE

No Results Yet

NCT04452474 | WITHDRAWN | PHASE2/PHASE3

0 participants

Study of the Efficacy and Safety of a Single Administration of Olokizumab vs. Placebo in Addition to Standard Treatment in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection (COVID-19).

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-06-30
Completion:: 2020-11-16

Conditions

COVID-19

Interventions

DRUG

No Results Yet

NCT04428775 | TERMINATED | PHASE2

12 participants

A Safety and Biomarker Study of ALZT-OP1a in Subjects With Mild-Moderate ALS Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-09-08
Completion:: 2021-10-01

Conditions

Amyotrophic Lateral Sclerosis

Interventions

DRUG

No Results Yet

NCT04422210 | TERMINATED | PHASE1

2 participants

A Study Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Venetoclax In Combination With Atezolizumab, Carboplatin, And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-09-22
Completion:: 2020-11-06

Conditions

Small Cell Lung Cancer

Interventions

DRUG

Results Available

NCT04392323 | COMPLETED | NA

111 participants

Incidence of COVID-19 Test Conversion in Post-surgical Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-05-13
Completion:: 2020-10-01

Conditions

Sars-CoV2

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04367909 | UNKNOWN | PHASE2

68 participants

A Study of TC(Docetaxel and Carboplatin) Regimen With or Without Nimotuzumab in Recurrent Metastatic Oral Squamous Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-06-21
Completion:: 2021-12-01

Conditions

Oral Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT04353206 | TERMINATED | EARLY_PHASE1

6 participants

Convalescent Plasma in ICU Patients With COVID-19-induced Respiratory Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-06-27
Completion:: 2020-11-01

Conditions

Covid-19
Sars-CoV2

Interventions

BIOLOGICAL

No Results Yet

NCT04339803 | COMPLETED | EARLY_PHASE1

19 participants

Dose-Finding of Lower Limb Mirror Therapy After Stroke.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-04-23
Completion:: 2021-08-09

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT04315311 | WITHDRAWN | PHASE4

0 participants

Study Of Effects Of Oral CREON Capsules In Adult Participants With Exocrine Pancreatic Insufficiency Not Due To Cystic Fibrosis, Chronic Pancreatitis, Pancreatectomy, Or Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-05-06
Completion:: 2021-09-22

Conditions

Exocrine Pancreatic Insufficiency (EPI)

Interventions

DRUG

No Results Yet

NCT04298918 | TERMINATED | PHASE1/PHASE2

1 participants

A Study Evaluating the Safety and Efficacy of Venetoclax in Combination With Trastuzumab Emtansine in Patients With Previously Treated HER2-Positive Locally Advanced or Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-09-23
Completion:: 2021-02-04

Conditions

Breast Cancer

Interventions

DRUG

Results Available

NCT04285255 | COMPLETED | NA

103 participants

Quality of Recovery Following Opioids Free Anaesthesia in Laparoscopic Sleeve Gastrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-03-01
Completion:: 2020-08-01

Conditions

Narcotics
Recovery Quality
Analgesia
Bariatric Surgery

Interventions

DRUG
PROCEDURE

No Results Yet

NCT04253665 | COMPLETED | NA

225 participants

Nursing Discharge Teaching for Multimorbid Inpatients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-08-13
Completion:: 2021-08-31

Conditions

Chronic Disease

Interventions

BEHAVIORAL

No Results Yet

NCT04245657 | COMPLETED

111 participants

Factors Affecting Functionality in Breast Cancer Survivors

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-12-17
Completion:: 2021-09-26

Conditions

Breast Cancer
Breast Cancer Female
Breast Cancer Lymphedema
Breast Carcinoma in Situ
Hand Grasp
Pain, Shoulder

Interventions

OTHER

No Results Yet

NCT04221425 | COMPLETED | NA

44 participants

Early Virtual Reality Based Home Rehabilitation Program After Total Hip Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-03-01
Completion:: 2021-02-16

Conditions

Osteoarthritis, Hip

Interventions

PROCEDURE

No Results Yet

NCT04196075 | COMPLETED | PHASE3

30 participants

The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2018-03-01
Completion:: 2021-02-28

Conditions

Squamous Cell Carcinoma of Esophagus

Interventions

DRUG

No Results Yet

NCT04161716 | COMPLETED | NA

40 participants

Study Evaluating the Ability of a NIRS Module to Detect a Urodynamic Variation in Humans (DETTECH)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2020-07-07
Completion:: 2021-09-30

Conditions

Urinary Disorders
Urinary Incontinence
Urinary Bladder Diseases

Interventions

DEVICE

No Results Yet

NCT04054570 | COMPLETED

947 participants

The Geneva Lake Study Update : An Overview of Home Non-Invasive Ventilation 15 Years Later

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-08
Start Date:: 2016-06-01
Completion:: 2018-07-10

Conditions

Home Non-Invasive Ventilation

Interventions

OTHER

No Results Yet

NCT04030182 | COMPLETED

127 participants

Vitamin D Deficit in Women With Uterine Fibroids

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-12-01
Completion:: 2021-10-09

Conditions

Leiomyoma
Vitamin D Deficiency
Fibroid Uterus

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03957070 | COMPLETED | NA

140 participants

The Sonic Incytes Liver Incyte System, Assessment of Liver Fibrosis and Steatosis

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-02-01
Completion:: 2021-04-01

Conditions

Liver Fibrosis
Liver Steatosis

Interventions

DEVICE

No Results Yet

NCT03952494 | WITHDRAWN | NA

0 participants

Individualizing Antidepressant Treatment Using Pharmacogenomics and EHR-driven Clinical Decision Support

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2022-03-01
Completion:: 2023-02-28

Conditions

Depression

Interventions

GENETIC

No Results Yet

NCT03923972 | UNKNOWN

1500 participants

Exercise Training and Physical Rehabilitation in Patients With Chronic Kidney Disease in Europe - What is the Problem?

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-05-15
Completion:: 2022-10-01

Conditions

Renal Insufficiency, Chronic
Kidney Failure, Chronic
Exercise

No Results Yet

NCT03900416 | COMPLETED | NA

152 participants

Adolescent Mindfulness Mobile App Study (RCT)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-06-17
Completion:: 2021-02-03

Conditions

Rumination
Depression
Anxiety
Self-Injurious Behavior

Interventions

BEHAVIORAL

Results Available

NCT03863483 | UNKNOWN | PHASE2

70 participants

A Study of Sintilimab or Placebo in Combination With Chemotherapy as Second-line Treatment for Patients With Stage IV Nonsquamous Non-small Cell Lung Cancer With Wild-type EGFR After Failure With Platinum-Containing Chemotherapy.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-03-26
Completion:: 2021-12-31

Conditions

Nonsquamous Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT03854552 | COMPLETED | PHASE1

72 participants

A Study in Healthy Men Tests How Different Doses of BI 764198 Are Taken up in the Body and How Well They Are Tolerated.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-03-15
Completion:: 2019-08-07

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT03845842 | COMPLETED | NA

311 participants

Using Implementation Intentions to Reduce Cannabis Use

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-02-14
Completion:: 2020-11-30

Conditions

Cannabis Use

Interventions

BEHAVIORAL

No Results Yet

NCT03840005 | COMPLETED | PHASE2

31 participants

Trial of Ursodeoxycholic Acid (UDCA) for Parkinson's Disease: The "UP" Study

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2018-12-18
Completion:: 2021-05-13

Conditions

Parkinson's Disease

Interventions

DRUG

No Results Yet

NCT03830411 | UNKNOWN | PHASE2

76 participants

A Study of Sintilimab Compared With Docetaxel or Pemetrexed as Second-line Treatment for Patients With Stage IV Nonsquamous Non-small Cell Lung Cancer After Failure With Platinum-Containing Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2019-03-13
Completion:: 2022-06-30

Conditions

Nonsquamous Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT03710785 | COMPLETED | NA

57 participants

Effect of Neck Extension Exercise Using 8 Channel Surface Electromyography

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-08
Start Date:: 2017-10-30
Completion:: 2020-09-18

Conditions

Neck Syndrome

Interventions

BEHAVIORAL

No Results Yet