Clinical Trials Updated in 2021

NCT03100045 | COMPLETED | PHASE1

18 participants

Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2017-04-20
Completion:: 2021-10-06

Conditions

HPV-Related Anal Intraepithelial Neoplasia
AIN2/3
Artesunate
Alternative Treatment
Anal Dysplasia
Precancerous Conditions
Human Papilloma Virus

Interventions

DRUG

No Results Yet

NCT02985450 | COMPLETED

82 participants

A Prospective Study of HBV Immunity and HBV Vaccination in Patients With NAFLD in Canada

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-03
Start Date:: 2016-08-31
Completion:: 2021-01-31

Conditions

Non-Alcoholic Fatty Liver Disease
Hepatitis B
Vaccine Reaction

Interventions

BIOLOGICAL

Results Available

NCT02948777 | COMPLETED | PHASE4

14 participants

Effects of PCSK9 Inhibition by Evolocumab on Postprandial Lipid Metabolism in Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2016-10-31
Completion:: 2018-06-30

Conditions

Type 2 Diabetes Mellitus

Interventions

DRUG

Results Available

NCT02941276 | COMPLETED | NA

84 participants

A Trial Looking at Treating Dry Mouth After Radiotherapy for Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2011-11-30
Completion:: 2014-11-30

Conditions

Xerostomia
Head and Neck Neoplasms

Interventions

DEVICE

No Results Yet

NCT02931539 | COMPLETED | PHASE3

352 participants

Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2016-12-22
Completion:: 2020-08-17

Conditions

Cytomegalovirus (CMV)

Interventions

DRUG

Results Available

NCT02805972 | COMPLETED | PHASE2

41 participants

Biology and Experience of Eating in Women With Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2017-05-20
Completion:: 2018-07-25

Conditions

Obesity

Interventions

DRUG

Results Available

NCT02660281 | COMPLETED | PHASE1

74 participants

URMC Related Haplo-identical Donor BMT

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2015-10-31
Completion:: 2019-10-28

Conditions

Hematological Disease
Immune Deficiencies
Solid Tumors
Myelofibrosis
Multiple Myeloma
Lymphoma

Interventions

RADIATION
DRUG
PROCEDURE

No Results Yet

NCT02571530 | TERMINATED | PHASE1

2 participants

Super-selective Intra-arterial Cerebral Infusion of Trastuzumab for the Treatment of Cerebral Metastases of HER2/Neu Positive Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2015-08-31
Completion:: 2021-06-30

Conditions

Neoplasm Metastasis

Interventions

DRUG

No Results Yet

NCT02438995 | TERMINATED | PHASE1

11 participants

Super-Selective Intraarterial Infusion of Cetuximab (Erbitux) With or Without Radiation Therapy for the Treatment of Unresectable Recurrent Squamous Cell Carcinoma of the Head and Neck

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2015-05-31
Completion:: 2021-06-30

Conditions

Carcinoma, Squamous Cell
Carcinoma, Squamous Cell of Head and Neck

Interventions

DRUG

No Results Yet

NCT02321670 | COMPLETED | NA

151 participants

Scandinavian Urethroplasty Study

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2015-09-30
Completion:: 2021-01-31

Conditions

Urethral Stricture

Interventions

PROCEDURE

No Results Yet

NCT02247193 | COMPLETED | PHASE1/PHASE2

30 participants

Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2015-12-31
Completion:: 2020-01-13

Conditions

Cleft Lip
Scarring
Cleft Palate

Interventions

DRUG

Results Available

NCT02232932 | UNKNOWN | NA

60 participants

Liver Resection Versus Radio-chemotherapy-Transplantation for Hilar Cholangiocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2014-03-31
Completion:: 2024-02-29

Conditions

Cholangiocarcinoma

Interventions

PROCEDURE

No Results Yet

NCT02232750 | COMPLETED

1320 participants

Evaluation of CPD MNV as an Aid in the Diagnosis and Risk Assessment of Sepsis (Protocol # Sepsis 1-14)

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-03
Start Date:: 2014-07-14
Completion:: 2015-08-15

Conditions

Sepsis, Severe Sepsis and Septic Shock

No Results Yet

NCT02226770 | COMPLETED | NA

132 participants

Heart-focused Anxiety in Patients With Heart Failure and ICD

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2010-07-14
Completion:: 2016-10-28

Conditions

Heart Failure Patients Before and After ICD Implantation

Interventions

DEVICE

No Results Yet

NCT02215512 | COMPLETED | PHASE1

29 participants

Dose-Escalation Study of RRx-001 in Combination With Whole Brain Radiation in Subjects With Brain Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2015-02-06
Completion:: 2016-11-28

Conditions

Brain Metastases

Interventions

DRUG

No Results Yet

NCT02084173 | COMPLETED | NA

704 participants

Treatment of Alcohol Problems in the Elderly

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2014-01-31
Completion:: 2017-06-30

Conditions

Alcohol Use Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT01939444 | COMPLETED | PHASE2

5 participants

A Pilot Study of the Bioavailability of Nasal Naloxone

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2013-08-31
Completion:: 2014-10-31

Conditions

Drug Overdose

Interventions

DRUG

No Results Yet

NCT01919489 | COMPLETED | PHASE4

273 participants

Liraglutide Hospital Discharge Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2014-03-31
Completion:: 2020-08-30

Conditions

Type 2 Diabetes

Interventions

DRUG

Results Available

NCT01899664 | COMPLETED | NA

17 participants

Upper Extremity Surgery in Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2012-06-30
Completion:: 2021-10-31

Conditions

Quadriplegia
Spinal Cord Diseases
Spinal Cord Injuries

Interventions

PROCEDURE

No Results Yet

NCT01857401 | COMPLETED

60 participants

Development of a Novel Human In Vitro Sarcoidosis Model

Study Type:: OBSERVATIONAL
Last Updated:: 2021-11-03
Start Date:: 2012-12-19
Completion:: 2017-02-02

Conditions

Sarcoidosis

Interventions

OTHER

No Results Yet

NCT01855048 | COMPLETED | PHASE1

36 participants

A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of N-Rephasin® SAL200 in Healthy Male Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2013-08-06
Completion:: 2014-02-07

Conditions

Healthy Volunteers
Anti-Bacterial Agents
Methicillin-Resistant Staphylococcus Aureus

Interventions

BIOLOGICAL
OTHER

Results Available

NCT01801241 | COMPLETED | NA

56 participants

Comparison of Glenoid Component Position Using Intelligent Reusable Instrument (IRI) vs Standard Surgical Instruments

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2013-01-31
Completion:: 2013-12-31

Conditions

Anatomic Total Shoulder Arthroplasty

Interventions

DEVICE
PROCEDURE

Results Available

NCT01780636 | TERMINATED | PHASE2/PHASE3

7 participants

Ultrasound and EMG Guided Botox Injection for the Treatment of Non-Relaxing Puborectalis Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2013-01-31
Completion:: 2014-01-31

Conditions

Non-relaxing Puborectalis Syndrome

Interventions

DRUG

Results Available

NCT01445535 | COMPLETED | PHASE1

15 participants

Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab in T- and NK-Cell Lymphomas

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2009-01-13
Completion:: 2011-04-01

Conditions

T-Cell Peripheral Lymphoma
Gamma Delta Hepatosplenic T-Cell Lymphoma
Subcutaneous Panniculitis-Like T-Cell Lymphoma
NK T-Cell Lymphoma

Interventions

BIOLOGICAL
DRUG

Results Available

NCT01038388 | COMPLETED | PHASE1

30 participants

A Study of the Combination Vorinostat With Lenalidomide, Bortezomib and Dexamethasone for Patients With Newly Diagnosed Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2010-01-15
Completion:: 2021-08-05

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT00921895 | COMPLETED | NA

128 participants

A Comparison of the RPS Adeno Detector IV to Viral Cell Culture at Detecting Adenoviral Conjunctivitis

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2009-06-30
Completion:: 2011-06-30

Conditions

Conjunctivitis

Interventions

DEVICE

Results Available

NCT00705718 | COMPLETED | NA

194 participants

Endurant Bifurcated and Aorto-Uni-Iliac (AUI) Stent Graft System

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2008-06-30
Completion:: 2012-09-30

Conditions

Abdominal Aortic Aneurysms

Interventions

DEVICE

Results Available

NCT00507559 | COMPLETED | NA

155 participants

The Pivotal Study of the Aptus Endovascular AAA Repair System

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2007-09-30
Completion:: 2010-03-31

Conditions

Abdominal Aortic Aneurysms (AAA)

Interventions

DEVICE

Results Available

NCT00459316 | COMPLETED | PHASE1/PHASE2

384 participants

Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and Youth

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2007-06-30
Completion:: 2013-03-31

Conditions

HIV Infections
Meningitis

Interventions

BIOLOGICAL

Results Available

NCT00413231 | COMPLETED | NA

160 participants

Valor II: The Valiant Thoracic Stent Graft System Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2006-12-31
Completion:: 2010-08-31

Conditions

Thoracic Aortic Aneurysm

Interventions

DEVICE

Results Available

NCT00074035 | COMPLETED | PHASE2

39 participants

Pentostatin in Treating Patients With Refractory Chronic Graft-Versus-Host Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 2003-12-31
Completion:: 2008-08-31

Conditions

Graft Versus Host Disease

Interventions

DRUG

Results Available

NCT00000947 | COMPLETED | NA

850 participants

A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Mycobacterium Avium-intracellulare Infection
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000876 | COMPLETED | PHASE1

12 participants

Safety and Effectiveness of CD4-IgG2 in HIV-Positive Children

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000844 | COMPLETED | NA

560 participants

A Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Three Preparations of Low-Dose Oral Alpha Interferon in HIV-Infected Patients With CD4+ Counts >= 50 and <= 350 Cells/mm3

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000821 | COMPLETED | PHASE1

78 participants

Subcutaneously Administered Aldesleukin ( Interleukin-2; IL-2 ) Therapy in HIV-Infected Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000817 | COMPLETED | NA

260 participants

The Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared With Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03
Start Date:: 1994-11-30

Conditions

HIV Infections
Peripheral Nervous System Disease

Interventions

DRUG
PROCEDURE

No Results Yet

NCT00000805 | COMPLETED | PHASE1

32 participants

A Pharmacokinetic and Tolerance Study of Oral Ganciclovir in HIV-Infected Children With Asymptomatic Cytomegalovirus Infection and Low CD4 Cell Counts or Quiescent Cytomegalovirus Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Cytomegalovirus Infections
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000796 | COMPLETED | NA

525 participants

A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections
Tuberculosis

Interventions

DRUG

No Results Yet

NCT00000788 | COMPLETED | PHASE1

24 participants

A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Candidiasis
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000763 | COMPLETED | PHASE1

42 participants

A Phase I Study of TNP-470 in the Treatment of AIDS-Associated Kaposi's Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Sarcoma, Kaposi
HIV Infections

Interventions

DRUG

No Results Yet