Clinical Trials

NCT02194985 | COMPLETED | PHASE3

84 participants

Open-Label Extension Study of the Long-Term Effects of Migalastat HCL in Patients With Fabry Disease

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2015-03-14

Completion:

2019-10-23

Conditions

• Fabry Disease

Interventions

• DRUG

Results Available

NCT02138214 | COMPLETED | PHASE2

117 participants

Central Neck Dissection in Patients With Clinical Node Negative Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2014-06-06

Completion:

2019-10-30

Conditions

• Stage I Papillary Thyroid Cancer
• Stage II Papillary Thyroid Cancer
• Stage III Papillary Thyroid Cancer

Interventions

• PROCEDURE
• OTHER

Results Available

NCT02132533 | COMPLETED | PHASE3

88 participants

Nifedipine for Acute Tocolysis of Preterm Labor

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2014-05-05

Completion:

2018-10-29

Conditions

• Preterm Labor

Interventions

• DRUG
• OTHER

Results Available

NCT01875523 | COMPLETED | PHASE1

36 participants

PK of Serelaxin in Severe Renal Impairment and ESRD

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2013-08-31

Completion:

2013-12-31

Conditions

• Renal Failure, Chronic
• End-Stage Renal Disease

Interventions

• DRUG

No Results Yet

NCT01740700 | COMPLETED | NA

30 participants

Zenith® p-Branch® OTS Multicenter Study

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2013-01-31

Completion:

2015-06-30

Conditions

• Aortic Aneurysm, Abdominal

Interventions

• DEVICE

No Results Yet

NCT01735968 | COMPLETED | PHASE1

56 participants

A Dose-finding Study of a Combination of Imatinib and BYL719 in the Treatment of 3rd Line GIST Patients

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2013-02-27

Completion:

2018-10-19

Conditions

• 3rd Line GIST

Interventions

• DRUG

No Results Yet

NCT01703390 | COMPLETED | PHASE2

47 participants

Biomarker Directed Treatment in Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2012-12-04

Completion:

2018-02-23

Conditions

• Metastatic Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT01700270 | COMPLETED | PHASE1

45 participants

Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors.

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2013-05-31

Completion:

2014-08-31

Conditions

• Advanced Solid Tumors, Excluding Breast Cancer

Interventions

• DRUG

No Results Yet

NCT01666106 | COMPLETED

327 participants

Osteonecrosis of the Jaw (ONJ) Case Registry

Study Type:

OBSERVATIONAL

Last Updated:

2020-12-21

Start Date:

2012-10-01

Completion:

2020-12-16

Conditions

• Osteonecrosis of the Jaw

No Results Yet

NCT01652547 | COMPLETED | PHASE1

10 participants

A Phase I, Exploratory, Intra-patient Dose Escalation Study to Investigate the Preliminary Safety, Pharmacokinetics, and Anti-tumor Activity of Pasireotide (SOM230) s.c.Followed by Pasireotide LAR in Patients With Metastaticmelanoma or Metastatic Merkel Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2012-11-30

Completion:

2015-04-30

Conditions

• Metastatic Melanoma and Merkel Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT01646684 | COMPLETED | PHASE1

9 participants

Phase 1 Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Pasireotide LAR in Patients With Castration Resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2013-03-08

Completion:

2018-11-13

Conditions

• Castration Resistant Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT01614717 | COMPLETED | NA

25 participants

Triple Chamber Pacing in Hypertrophic Obstructive Cardiomyopathy (HOCM) Patients - TRICHAMPION STUDY

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2014-07-31

Completion:

2020-09-30

Conditions

• Hypertrophic Cardiomyopathy With Obstruction

Interventions

• DEVICE

No Results Yet

NCT01596647 | COMPLETED | PHASE1

39 participants

Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2012-05-31

Completion:

2014-07-31

Conditions

• Advanced Solid Tumors, Excluding Breast Cancer

Interventions

• DRUG

No Results Yet

NCT01578928 | COMPLETED | PHASE1

50 participants

A Phase l Study to Evaluate the Pharmacokinetics and Safety Pasireotide in Subjects With Varying Degrees of Renal Impairment Compared to Healthy Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2012-05-31

Completion:

2014-05-31

Conditions

• Renal Impairment

Interventions

• DRUG

No Results Yet

NCT01568762 | COMPLETED | PHASE1

50 participants

To Compare the Safety, Tolerability, and Pharmacokinetics of QBX258 in Patients With Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2010-10-31

Completion:

2011-07-31

Conditions

• Asthma

Interventions

• DRUG

No Results Yet

NCT01529307 | TERMINATED | PHASE1

6 participants

First in Human Trial of TAS266 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2012-06-30

Completion:

2012-09-30

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT01487460 | COMPLETED | PHASE1

137 participants

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAP311 in Healthy Subjects and Dyslipidemic Patients

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2011-11-30

Completion:

2012-06-30

Conditions

• Dyslipidemia
• Healthy Volunteers

Interventions

• DRUG

No Results Yet

NCT01482156 | COMPLETED | PHASE1

46 participants

Dose Finding Study of RAD001 (Everolimus, Afinitor®) in Combination With BEZ235 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2012-01-31

Completion:

2015-02-28

Conditions

• Advanced Solid Tumors
• Metastatic Breast Cancer
• Metastatic Renal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT01471548 | COMPLETED | PHASE1

31 participants

Phase I Dose Escalating Study of TKI258

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2008-09-30

Completion:

2012-05-31

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT01468688 | COMPLETED | PHASE1

60 participants

A Dose-finding Study of a Combination of Imatinib and BKM120 in the Treatment of 3rd Line GIST Patients

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2012-04-20

Completion:

2016-07-29

Conditions

• 3rd Line GIST

Interventions

• DRUG

No Results Yet

NCT01447485 | COMPLETED | PHASE1

12 participants

Pharmacokinetics Following Single-dose of Valsartan in Japanese Pediatric Patients

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2011-08-31

Completion:

2011-10-31

Conditions

• Hypertension
• Chronic Kidney Disease
• Nephrotic Syndrome

Interventions

• DRUG

No Results Yet

NCT01443481 | COMPLETED | PHASE1

38 participants

Pharmacokinetics (PK) of TKI258 in Cancer Patients With Normal and Impaired Hepatic Function

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2011-11-30

Completion:

2014-10-31

Conditions

• Solid Tumors
• Hepatic Impairment

Interventions

• DRUG

No Results Yet

NCT01433458 | COMPLETED | PHASE1

55 participants

Pharmacokinetics of RLX030 in Subjects With Mild, Moderate and Severe Hepatic Impairment Compared to Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2011-07-31

Completion:

2011-12-31

Conditions

• Hepatic Impairment

Interventions

• DRUG

No Results Yet

NCT01421004 | COMPLETED | PHASE1

166 participants

Bioequivalence of 2 Formulations of TKI258 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2011-12-31

Completion:

2014-07-31

Conditions

• Advanced Solid Tumors
• Excluding Breast Cancer

Interventions

• DRUG

No Results Yet

NCT01371890 | COMPLETED

18 participants

Mechanisms and Treatment of Intradialytic Hypertension - Sodium

Study Type:

OBSERVATIONAL

Last Updated:

2020-12-21

Start Date:

2011-05-31

Completion:

2012-08-31

Conditions

• Hemodialysis
• End-stage Renal Disease
• Hypertension
• Intradialytic Hypertension

No Results Yet

NCT01364415 | COMPLETED | PHASE1

29 participants

Dose Escalation Study of Pasireotide (SOM230) in Patients With Advanced Neuroendocrine Tumors (NETs)

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2011-08-31

Completion:

2016-04-30

Conditions

• Neuroendocrine Tumors

Interventions

• DRUG

No Results Yet

NCT01263353 | COMPLETED | PHASE1

36 participants

Safety and Tolerability of Pasireotide LAR in Combination With Everolimus in Advanced Metastatic NETs

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2010-11-30

Completion:

2014-03-31

Conditions

• Gastroenteropancreatic Neuroendocrine Tumor of the Pulmonary ot Gastroenteropancreatic System

Interventions

• DRUG

No Results Yet

NCT01242241 | COMPLETED | PHASE3

80 participants

Propofol in Obese Children

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2008-04-01

Completion:

2011-12-31

Conditions

• Pharmacodynamics
• Obesity

Interventions

• DRUG

Results Available

NCT01225341 | TERMINATED | NA

20 participants

Botulinum Toxin A for Herpes Labialis

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2010-08-31

Completion:

2012-05-31

Conditions

• Herpes Labialis

Interventions

• DRUG
• OTHER

Results Available

NCT01155713 | COMPLETED | PHASE1

63 participants

Bioavailability and Food Effect Study of TKI258 (CSF Capsule vs. FMI Tablet) in Adult Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2010-07-31

Completion:

2013-11-30

Conditions

• Neoplasm
• Cancer
• Tumors

Interventions

• DRUG

No Results Yet

NCT01152801 | COMPLETED | PHASE1

64 participants

Safety of RAD001 in Chinese Patients With Metastatic Renal Cell Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2010-05-31

Completion:

2013-12-31

Conditions

• Metastatic Renal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT01101997 | COMPLETED | NA

60 participants

Non-Invasive Reduction of Abdominal Fat

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2010-03-30

Completion:

2010-09-28

Conditions

• Fat Reduction

Interventions

• DEVICE

Results Available

NCT01098682 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:

2020-12-21

No Results Yet

NCT01030055 | COMPLETED | PHASE1

60 participants

Bioavailability and Food Effect Study of TKI258 (CSF Capsules vs. FMI Capsules)in Adult Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2010-02-28

Completion:

2012-06-30

Conditions

• Neoplasms
• Cancer
• Tumors

Interventions

• DRUG

No Results Yet

NCT00968591 | COMPLETED | PHASE1

34 participants

Pharmacokinetics of Everolimus in Subjects With Hepatic Insufficiency

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2009-11-30

Completion:

2010-11-30

Conditions

• Hepatic Insufficiency

Interventions

• DRUG

No Results Yet

NCT00940160 | COMPLETED | PHASE1/PHASE2

30 participants

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QAX576 in Asthma Patients

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2009-07-31

Completion:

2010-01-31

Conditions

• Asthma

Interventions

• DRUG

No Results Yet

NCT00933920 | COMPLETED | PHASE1

124 participants

Effect of Light Meal on Pharmacokinetic and Pharmacodynamics of Aliskiren in Patients With Mild to Moderate Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2009-06-30

Completion:

2009-12-31

Conditions

• Hypertension

Interventions

• DRUG

No Results Yet

NCT00876863 | COMPLETED | PHASE2

49 participants

Randomized, Controlled Study Evaluating CERE-110 in Subjects With Mild to Moderate Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2008-11-30

Completion:

2015-08-13

Conditions

• Alzheimer's Disease

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT00853203 | UNKNOWN

174 participants

Expressive Disclosure and Colorectal Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2020-12-21

Start Date:

2009-01-31

Completion:

2021-08-31

Conditions

• Colorectal Cancer

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT00715182 | COMPLETED | PHASE1

87 participants

A Phase I/II Study to Assess the Safety and Efficacy of TKI258 for the Treatment of Refractory Advanced/Metastatic Renal Cell Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-21

Start Date:

2008-07-31

Completion:

2012-07-31

Conditions

• Advanced/ Metastatic Renal Cell Cancer

Interventions

• DRUG

No Results Yet