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A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

NCT07805707 · Status: NOT_YET_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 54000

Last updated 2026-09-04

No results posted yet for this study

Summary

This study will compare an investigational mRNA flu vaccine with a licensed flu vaccine in adults 65 years of age and older. Participants will receive one injection and will be followed during the flu season. The study will measure prevention of laboratory-confirmed flu illness, side effects, and immune responses.

Conditions

  • Influenza, Human

Interventions

COMBINATION_PRODUCT

mRNA Seasonal Flu vaccine

Single-dose intramuscular administration of the season-adapted investigational mRNA Seasonal Flu vaccine.

COMBINATION_PRODUCT

Licensed Influenza Vaccine

Single-dose intramuscular administration of an age-appropriate and season-adapted licensed influenza vaccine used as the active comparator.

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-09-02
Primary Completion
2028-06-09
Completion
2028-06-09
FDA Drug
Yes

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07805707 on ClinicalTrials.gov