Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
NCT07804524 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2026-09-04
Summary
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in patients with pulmonary arterial hypertension PAH, who live permanently \>2600m.
Conditions
- Pulmonary Arterial Hypertension (PAH)
- Pulmonary Vascular Disease
- High Altitude
- Echocardiography
- Pulmonary Resistance
- Hemodynamic Changes
Interventions
- BEHAVIORAL
-
Descent from 2850m to sea level
Descent from 2850m to sea level with a stay for 7 days
Sponsors & Collaborators
-
Silvia Ulrich Somaini
lead OTHER
Principal Investigators
-
Silvia Ulrich · University Hospital Zurich, Departement of Pulmonology
-
Rodrigo Hoyos · Hospital Carlos Andrade Marin of Quito, Ecuador
Study Design
- Allocation
- NA
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-09-25
- Primary Completion
- 2026-10-04
- Completion
- 2026-12-31
Countries
- Switzerland
Study Locations
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