A Study of Armored CAR T Cells in People With Cancer
NCT07783477 · Status: NOT_YET_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2026-08-28
Summary
The purpose of this study is to test the safety of DLL3-SAVVYZ-IL18 in people with DLL3+ cancer.
Conditions
- Neuroendocrine Cancer
- Small Cell Lung Cancer
- Small Cell Lung Cancer ( SCLC )
Interventions
- DRUG
-
DLL3-SAVVYZ-IL18 CAR T cell
DLL3-SAVVYZ-IL18 CAR T cell
Sponsors & Collaborators
-
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Adam Schoenfeld, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-09-30
- Primary Completion
- 2029-09-30
- Completion
- 2029-09-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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