Understanding (Poly)Phenol Metabolism in People With an Ileostomy
NCT07772362 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2026-08-19
Summary
Plant foods contain natural compounds called (poly)phenols, which may help lower the risk of heart and metabolic diseases. However, people differ greatly in how they absorb and process these compounds, partly because most (poly)phenols are broken down by gut bacteria in the colon. This makes it difficult to know exactly which metabolites come from the diet, and which are produced by the body. Studying people with an ileostomy provides a unique opportunity to understand how much is absorbed in the small intestine and how these compounds are transformed. This will help us better understand individual responses to dietary (poly)phenols.
Conditions
- Ileostomy - Stoma
Interventions
- DIETARY_SUPPLEMENT
-
(Poly)phenol rich capsules
(Poly)phenol rich capsules (\~3 g)
Sponsors & Collaborators
-
University of Parma
collaborator OTHER -
University of Ulster
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-08-31
- Primary Completion
- 2028-05-31
- Completion
- 2028-05-31
Countries
- United Kingdom
Study Locations
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