Understanding (Poly)Phenol Metabolism in People With an Ileostomy

NCT07772362 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-08-19

No results posted yet for this study

Summary

Plant foods contain natural compounds called (poly)phenols, which may help lower the risk of heart and metabolic diseases. However, people differ greatly in how they absorb and process these compounds, partly because most (poly)phenols are broken down by gut bacteria in the colon. This makes it difficult to know exactly which metabolites come from the diet, and which are produced by the body. Studying people with an ileostomy provides a unique opportunity to understand how much is absorbed in the small intestine and how these compounds are transformed. This will help us better understand individual responses to dietary (poly)phenols.

Conditions

  • Ileostomy - Stoma

Interventions

DIETARY_SUPPLEMENT

(Poly)phenol rich capsules

(Poly)phenol rich capsules (\~3 g)

Sponsors & Collaborators

  • University of Parma

    collaborator OTHER
  • University of Ulster

    lead OTHER

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-31
Primary Completion
2028-05-31
Completion
2028-05-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07772362 on ClinicalTrials.gov