Comprehensive Kidney Function Assessment and Early Warning in Older Adults

NCT07765134 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 5588

Last updated 2026-08-14

No results posted yet for this study

Summary

This completed observational cohort study evaluates a comprehensive set of clinical and molecular markers of kidney function in two established cohorts of Chinese adults aged 60 years or older. The study assesses markers reflecting glomerular filtration, kidney tubular transport, and kidney endocrine function and evaluates their associations with kidney failure, cardiovascular and cerebrovascular events, and all-cause mortality. It also compares approaches to estimating glomerular filtration rate and develops and internally validates an early-warning model for kidney function decline. Existing baseline and follow-up data and stored serum and urine specimens are used. No intervention or additional study-specific clinical procedure is administered.

Conditions

Sponsors & Collaborators

  • Huashan Hospital

    lead OTHER

Principal Investigators

  • Jing Chen · Huashan Hospital

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-12-10
Primary Completion
2022-09-06
Completion
2022-09-06

Countries

  • China

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07765134 on ClinicalTrials.gov