Gentle Skin Abrasion and EMG-Based Neuromuscular Blockade Monitoring

NCT07759206 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2026-08-12

No results posted yet for this study

Summary

This study will evaluate whether gentle skin abrasion improves electromyographic signal quality during neuromuscular blockade monitoring in adult surgical patients.

Participants will receive standard TwitchView electromyographic neuromuscular blockade monitoring on one wrist and TwitchView monitoring after gentle skin abrasion on the opposite wrist. The study will compare electromyographic response amplitudes and supramaximal stimulus currents between routine electrode application and electrode application after skin preparation.

The study procedures will occur during scheduled surgery and will not alter the anesthetic or surgical management of participants.

Conditions

  • Neuromuscular Blockade
  • Intraoperative Monitoring
  • Skin Preparation
  • Electromyography

Interventions

PROCEDURE

Gentle Skin Abrasion Before EMG-Based Neuromuscular Blockade Monitoring

Gentle skin abrasion will be performed at the stimulus and recording electrode sites on one wrist using 3M Red Dot Trace Prep abrasive strips before applying standard TwitchView electrodes. The opposite wrist will receive routine electrode application without skin preparation. Two TwitchView monitors will be used to compare EMG signal amplitudes and supramaximal stimulus currents.

Sponsors & Collaborators

Principal Investigators

  • Michael M Todd, MD · University of Minnesota

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-03
Primary Completion
2024-02-28
Completion
2024-02-28

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07759206 on ClinicalTrials.gov