Gentle Skin Abrasion and EMG-Based Neuromuscular Blockade Monitoring
NCT07759206 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 55
Last updated 2026-08-12
Summary
This study will evaluate whether gentle skin abrasion improves electromyographic signal quality during neuromuscular blockade monitoring in adult surgical patients.
Participants will receive standard TwitchView electromyographic neuromuscular blockade monitoring on one wrist and TwitchView monitoring after gentle skin abrasion on the opposite wrist. The study will compare electromyographic response amplitudes and supramaximal stimulus currents between routine electrode application and electrode application after skin preparation.
The study procedures will occur during scheduled surgery and will not alter the anesthetic or surgical management of participants.
Conditions
- Neuromuscular Blockade
- Intraoperative Monitoring
- Skin Preparation
- Electromyography
Interventions
- PROCEDURE
-
Gentle Skin Abrasion Before EMG-Based Neuromuscular Blockade Monitoring
Gentle skin abrasion will be performed at the stimulus and recording electrode sites on one wrist using 3M Red Dot Trace Prep abrasive strips before applying standard TwitchView electrodes. The opposite wrist will receive routine electrode application without skin preparation. Two TwitchView monitors will be used to compare EMG signal amplitudes and supramaximal stimulus currents.
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Michael M Todd, MD · University of Minnesota
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-10-03
- Primary Completion
- 2024-02-28
- Completion
- 2024-02-28
Countries
- United States
Study Locations
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