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Early Versus Delayed Ileostomy Closure Following Bowel Surgery: A Randomized Controlled Trial

NCT07754227 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 73

Last updated 2026-08-10

No results posted yet for this study

Summary

Temporary ileostomy is commonly created following bowel surgery to protect distal anastomoses and reduce the consequences of anastomotic leakage. However, the optimal timing for ileostomy closure remains controversial. Early closure may improve quality of life and reduce stoma-related complications, whereas delayed closure may allow better recovery but prolong stoma-related morbidity and hospital care. This randomized controlled trial aims to compare the mean post-operative hospital stay between early (within 8 weeks) and delayed (after 8 weeks) ileostomy closure following bowel surgery. Sixty eligible patients will be randomized equally into two groups. The findings will help determine the optimal timing of ileostomy reversal and may improve patient outcomes while reducing healthcare utilization.

Conditions

  • Colorectal Diseases
  • Intestinal Diseases
  • Ileostomy

Interventions

PROCEDURE

Early Ileostomy Closure

Surgical reversal of temporary ileostomy performed within 8 weeks after ileostomy creation.

PROCEDURE

Delayed Ileostomy Closure

Surgical reversal of temporary ileostomy performed more than 8 weeks after ileostomy creation.

Sponsors & Collaborators

  • Dr. Waseem Ullah

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-02
Primary Completion
2026-07-05
Completion
2026-07-08

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07754227 on ClinicalTrials.gov