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Risk Factors for Postoperative Nausea and Vomiting After Nasal Surgery Under General Anesthesia

NCT07749079 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2026-08-06

No results posted yet for this study

Summary

The goal of this observational study is to learn how often postoperative nausea and vomiting occur in adults undergoing nasal surgery under general anesthesia and to identify factors associated with these events. The study will also describe other postoperative complications and factors that may affect recovery.

The main questions it aims to answer are:

* How many participants experience nausea, retching, or vomiting within 24 hours after surgery?
* Which patient characteristics, anesthesia-related factors, surgical factors, and perioperative medications are associated with postoperative nausea and vomiting?
* What other postoperative complications and nasal-related symptoms occur after surgery?

Approximately 1,000 adults undergoing nasal surgery under general anesthesia at three hospitals in China will be enrolled. This is an observational study, and participation will not change the anesthesia, surgery, medications, or other medical care selected by the treating clinical team.

Participants will:

* Complete assessments before surgery about their medical history, previous nausea or vomiting, anxiety, sleep, and recovery status
* Receive routine anesthesia and surgical care
* Be assessed for nausea, retching, vomiting, pain, nasal discomfort, and other complications during the first 24 hours after surgery
* Complete follow-up assessments after surgery, including follow-up by telephone after discharge, for up to 6 months

The study will use information from participant questionnaires, medical records, anesthesia records, and postoperative follow-up assessments.

Conditions

  • PONV

Sponsors & Collaborators

  • Eye & ENT Hospital of Fudan University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-01
Primary Completion
2026-12-31
Completion
2027-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07749079 on ClinicalTrials.gov