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Photon-Counting CT for Detection of Small Gastrointestinal Lesions

NCT07748923 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1762

Last updated 2026-08-10

No results posted yet for this study

Summary

This comparative matched-cohort study aims to evaluate the diagnostic performance of contrast-enhanced photon-counting computed tomography (PCCT) for detecting small gastrointestinal lesions compared with energy-integrating detector dual-energy computed tomography (DECT). The study includes a prospectively enrolled PCCT cohort and a retrospectively identified DECT cohort. Endoscopy with histopathology serves as the reference standard. Primary evaluation focuses on lesion detection, with additional assessment of lesion characterization, image quality, quantitative imaging parameters, and interobserver agreement.

Conditions

  • Gastrointestinal Lesions

Interventions

DIAGNOSTIC_TEST

Contrast-Enhanced Photon-Counting Computed Tomography

Contrast-enhanced abdominal photon-counting computed tomography performed for the detection and characterization of small gastrointestinal lesions.

DIAGNOSTIC_TEST

Contrast-Enhanced Energy-Integrating Detector Dual-Energy Computed Tomography

Contrast-enhanced abdominal energy-integrating detector dual-energy computed tomography performed for comparison of diagnostic performance in detecting and characterizing small gastrointestinal lesions.

Sponsors & Collaborators

  • The Second Affiliated Hospital of Chongqing Medical University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-18
Primary Completion
2026-01-09
Completion
2026-05-21

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07748923 on ClinicalTrials.gov