Retrospective Study of Romiplostim for Platelet Engraftment After Allo-HSCT
NCT07747246 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 103
Last updated 2026-08-05
Summary
This is a retrospective observational study evaluating the efficacy and safety of romiplostim for promoting platelet engraftment in patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) at Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology between January 2025 to May 2026. Medical records were reviewed to collect data on platelet recovery time, transfusion requirements, and adverse events. The primary endpoint was time to platelet engraftment. Secondary endpoints included platelet recovery kinetics, transfusion requirements, transplant-related complications, and safety outcomes.No interventions were assigned as part of this study.
Conditions
Sponsors & Collaborators
-
Tongji Hospital
lead OTHER
Principal Investigators
-
wen · Tongji Hospital Affiliated to Tongji Medical College of Huaz- hong University of Science and Technology
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-01-01
- Primary Completion
- 2026-05-01
- Completion
- 2026-07-15
Countries
- China
Study Locations
More Related Trials
-
Eltrombopag For Secondary Poor Graft Function Post Allogeneic Hematopoietic Stem Cell Transplantation
NCT03437603 ·Status: UNKNOWN ·Phase: PHASE2
-
The Prospective Randomized Controlled Study of Eltrombopag on Hematopoietic Reconstruction After Allogeneic HSCT
NCT03902041 ·Status: UNKNOWN
-
Safety of Romiplostim (Nplate®) Following UCBT
NCT02046291 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Lusutrombopag After Allogeneic Hematopoietic Stem Cell Transplantation
NCT07483385 ·Status: RECRUITING ·Phase: NA
-
UI-Romi-02; Romiplostim Added to Standard of Care for Treatment Naive and Relapsed or Refractory Severe Aplastic Anemia
NCT07001254 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Allo HSCT Using RIC and PTCy for Hematological Diseases
NCT05805605 ·Status: RECRUITING ·Phase: PHASE2
-
Eltrombopag for Post Transplant Thrombocytopenia
NCT01000051 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Followed By Donor Stem Cell Transplant in Treating Patients With Hemophagocytic Lymphohistiocytosis
NCT00334672 ·Status: UNKNOWN ·Phase: PHASE3
-
Efficacy and Safety of rHuTPO on Platelet Engraftment After Allo-HSCT
NCT01379391 ·Status: UNKNOWN ·Phase: PHASE4
-
Stem Cell Transplantation for Patients With Hematologic Malignancies
NCT00152139 ·Status: COMPLETED ·Phase: PHASE3
-
TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT
NCT07302776 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic Malignancies
NCT00013533 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Pentostatin, Cyclophosphamide Plus Rituximab (PCR) for the Therapy of Poor-Prognosis Chronic Graft-Versus-Host Disease
NCT01001780 ·Status: WITHDRAWN ·Phase: PHASE2
-
CC-4047 (Pomalidomide) for Graft vs. Host Disease
NCT00770757 ·Status: COMPLETED ·Phase: PHASE2
-
Salvage Haploidentical HSCT With DLI and Targeted Therapy for R/R AML
NCT07572695 ·Status: NOT_YET_RECRUITING
-
Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia
NCT06517641 ·Status: RECRUITING ·Phase: PHASE2
-
Pharmacokinetics-based Mycophenolate Mofetil Dosing for GVHD Prevention
NCT01487577 ·Status: COMPLETED ·Phase: PHASE2
-
Framework for Optimizing, Refining, and Unifying Management of HSCT in Pediatric ALL
NCT07297914 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors
NCT02653196 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases
NCT03367546 ·Status: TERMINATED ·Phase: PHASE2
-
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide in Patients With Acquired Refractory Aplastic Anemia or in Relapse After Immunosuppression
NCT05126849 ·Status: RECRUITING ·Phase: PHASE2
-
Eltrombopag Olamine in Increasing Platelet Counts in Patients Undergoing Transplant
NCT01927731 ·Status: COMPLETED ·Phase: PHASE2
-
Fludarabine and Total Body Irradiation 800 Centigray (cGy) or 1125 cGy For Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil
NCT05256537 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Prophylactic HQP1351 Therapy Post-transplants on Leukemia After Allo-HSCT
NCT05604755 ·Status: WITHDRAWN ·Phase: PHASE2
-
Stem Cell Mobilization and Apheresis for Life-threatening Blood Disorders
NCT07585136 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1