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Effect of PNF + Core Strengthening Exercise in Sub-acute Guillain Barre Syndrome

NCT07745556 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2026-08-07

No results posted yet for this study

Summary

This randomized controlled trial will evaluate the effectiveness of proprioceptive neuromuscular facilitation combined with core strengthening exercises in Guillain barre syndrome patients on balance, strength and ADLS. A total of 32 participants will be recruited using purposive sampling and randomly assigned into two groups through the sealed envelope method. Balance will be assessed using berg balance scale, strength will be measured by MMT and ADLS will measure by berthal index at baseline and after completion of the intervention participants in the experimental group will receive PNF + core strengthening exercise four times in week for eight weeks, and conventional physical therapy will perform on control group .

Conditions

  • Guillain Barré Syndrome

Interventions

BEHAVIORAL

Proprioceptive neuromuscular facilitation combined with core strengthening exercise

Participants will receive Proprioceptive Neuromuscular Facilitation (PNF) using the Contract-Relax (CR) and Contract-Relax Agonist-Contract (CRAC) techniques for both upper and lower extremities. Each repetition consists of a 10-20 second passive or active stretch, followed by a 3-6 second isometric contraction against therapist resistance, and then a further stretch to the newly gained range of motion. In addition, participants will perform progressive core strengthening exercises, including pelvic control exercises, curl-ups, bridging (including single-leg and crossed-leg variations), and side bridging. Participants will be instructed to activate the transversus abdominis and multifidus muscles throughout the exercises to improve trunk stability, balance, muscle strength, and functional independence.

BEHAVIORAL

conventional physiotherapy

The conventional therapy included stretching and strengthening of upper and lower extremities, techniques to normalize the muscle tone, weight bearing exercises, active functional training to enhance postural and functional control and conventional balance training. The program included four sessions per week for eight weeks with duration of each session of about 45 minutes which included warm up of 5 minutes, conventional therapy for 35 minutes and cool down of 5 minutes with 1-2 minute rest between the tasks.

Sponsors & Collaborators

  • Rida

    lead OTHER

Principal Investigators

  • Rida Rao, MSPTN · The University of Lahore , Lahore

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-15
Primary Completion
2026-04-15
Completion
2026-04-18

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07745556 on ClinicalTrials.gov