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Evaluating Facial Skin Quality Changes Post-Lipofilling

NCT07737639 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2026-07-30

No results posted yet for this study

Summary

The goal of this prospective observational study is to evaluate changes in facial skin quality and identify predictive biological markers in donor adipose tissue in healthy women undergoing autologous facial fat transfer. The main questions it aims to answer are:

How does full-face lipofilling alter clinical signs of aging, such as wrinkles, sagging, and skin texture, over a 6-month period? Which baseline biological characteristics (e.g., cellular stemness, extracellular matrix remodeling, angiogenesis) within the donor fat graft predict these clinical skin quality outcomes?

Participants will:

Undergo a standard full-face autologous fat transfer (lipofilling) procedure. Attend follow-up evaluation visits at 1.5, 3, and 6 months post-procedure. Undergo non-invasive clinical and instrumental skin assessments (e.g., standardized photography, 3D topography, echography, and cutometry).

Complete self-assessment questionnaires regarding perceived skin changes and overall satisfaction with the procedure.

Conditions

  • Facial Aging

Sponsors & Collaborators

  • Hospices Civils de Lyon

    collaborator OTHER

  • L'Oreal

    lead INDUSTRY

Principal Investigators

  • Stephanie Nouveau · L'Oreal

Eligibility

Min Age
30 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-10
Primary Completion
2023-11-10
Completion
2024-09-10

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07737639 on ClinicalTrials.gov