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Ruscus Evaluation for Symptom Control in Uncomplicated Chronic Venous Insufficiency

NCT07737236 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 564

Last updated 2026-07-31

No results posted yet for this study

Summary

This multicenter, prospective, observational study aims to generate and analyze real-world data on the effectiveness and safety of Ruscus aculeatus L. treatment in patients with symptomatic chronic venous disease classified as CEAP C1-C6. Patients receiving Ruscus aculeatus L. as part of routine clinical practice will be followed for 90 days without any study-mandated intervention. Disease severity will be assessed using the revised Venous Clinical Severity Score (rVCSS), pain using the Visual Analog Scale (VAS), quality of life using the Chronic Venous Disease Quality of Life Questionnaire (CIVIQ-20), treatment adherence using the Visual Analog Scale for adherence (VAS-U), and safety through the collection of adverse events during the observation period.

Conditions

  • Chronic Venous Disease

Sponsors & Collaborators

  • Turkish Society for Vascular and Endovascular Surgery

    lead OTHER

Principal Investigators

  • Nevzate Erdil, MD · Antalya City Hospital

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-06-02
Primary Completion
2027-06-01
Completion
2027-06-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07737236 on ClinicalTrials.gov