A Study of VV-14303 for the Treatment of Metabolic Dysfunction-associated Steatohepatitis (MASH)
NCT07732400 · Status: NOT_YET_RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 56
Last updated 2026-07-28
Summary
A Study of VV-14303 for the Treatment of Metabolic dysfunction-associated steatohepatitis (MASH)
Conditions
- Metabolic Dysfunction-associated Steatohepatitis (MASH)
Interventions
- GENETIC
-
VV-14303
will be administered via ultrasound guided intramuscular injections
Sponsors & Collaborators
-
Kriya Therapeutics, Inc.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-07-31
- Primary Completion
- 2028-07-31
- Completion
- 2029-07-31
- FDA Drug
- Yes
Countries
- United States
- New Zealand
Study Locations
More Related Trials
-
A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
NCT06920043 ·Status: RECRUITING ·Phase: PHASE2
-
Trial of Mesenchymal Stem Cell Transplantation in Decompensated Liver Cirrhosis
NCT03209986 ·Status: UNKNOWN ·Phase: NA
-
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH
NCT07335601 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Refractory Primary Biliary Cirrhosis
NCT01440309 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of ADR-001 in Patients With Liver Cirrhosis
NCT03254758 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
S-Adenosylmethionine Therapy for Non-Alcoholic Steatohepatitis
NCT00108589 ·Status: COMPLETED ·Phase: PHASE3
-
Dose Finding Study to Assess Safety and Efficacy of Stem Cells in Liver Cirrhosis
NCT01591200 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 3 Study Evaluating the Safety and Efficacy of HSK31679 in Patients With MASH
NCT07581951 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Intra-hepatic Artery Bone Marrow Derived Stem Cells Infusion for the Treatment of Advanced Liver Cirrhosis
NCT01412593 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)
NCT07528690 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Safety Study of Liver Regeneration Therapy Using Cultured Autologous BMSCs
NCT02327832 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Decompensated Hepatitis B Cirrhosis
NCT05948982 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Phase I/II Study of Recombinant Human Hepatocyte Growth Factor in Fulminant Hepatic Failure
NCT00225901 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Long Term Follow up Mesenchymal Stem Cell Therapy for Patients Virus-related Liver Cirrhosis
NCT05080465 ·Status: COMPLETED ·Phase: PHASE3
-
Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-1b)
NCT05984303 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety and Efficacy Study of Umbilical Mesenchymal Stem Cells for Liver Cirrhosis
NCT01573923 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Improvement of Liver Function in Liver Cirrhosis Patients After Autologous Mesenchymal Stem Cell Injection:a Phase I-II Clinical Trial
NCT00420134 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Clinical Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of HCL001 Cell Injection (Homologous Allogeneic Hepatocytes) in Patients With Decompensated Cirrhosis
NCT06306781 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Liver Regeneration Therapy Using Autologous Adipose Tissue Derived Stromal Cells
NCT00913289 ·Status: TERMINATED ·Phase: PHASE1
-
Safety and Efficacy of Diverse Mesenchymal Stem Cells Transplantation for Liver Failure
NCT01844063 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of Recombinant Human FGF21-Fc Fusion Protein for Injection (TQA2225/AP025) in Adult Subjects With Non-alcoholic Steatohepatitis (NASH)
NCT06569524 ·Status: RECRUITING ·Phase: PHASE2
-
Mesenchymal Stem Cell Therapy for Liver Cirrhosis
NCT03626090 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
To Evaluate the Tolerability, Pharmacokinetics, and Pharmacodynamics of IMM-H014 in Patients With MASH
NCT07016633 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Study to Evaluate Hepatic Artery Injection of Autologous Human Bone Marrow-Derived MSCs in Patients With Alcoholic LC
NCT03838250 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety and Effectiveness of Mesenchymal Stem Cells in Blood Purification for the Treatment of Liver Failure
NCT06904755 ·Status: RECRUITING ·Phase: PHASE1