MedTrace Logo

Nociception Level Index Monitoring During Cesarean Section

NCT07720440 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-07-22

No results posted yet for this study

Summary

This prospective randomized controlled trial evaluated the effect of nociception level (NOL) index-guided intraoperative analgesia on postoperative pain management in patients undergoing elective cesarean section under general anesthesia. Sixty patients were randomly assigned to either NOL-guided analgesia or standard intraoperative monitoring. The primary outcome was postoperative pain intensity assessed using the visual analog scale (VAS) during the first 24 hours after surgery. Secondary outcomes included postoperative opioid requirements and time to first breastfeeding. The study aimed to determine whether objective intraoperative nociception monitoring could improve postoperative analgesia and enhance early maternal recovery.

Conditions

  • Cesarean Section
  • Postoperative Pain After Cesarean Section
  • Pain Management

Interventions

DEVICE

Nociception Level Index Monitoring

The Nociception Level (NOL) index was used to guide intraoperative fentanyl administration after fetal delivery.

OTHER

Standard Intraoperative Monitoring

Standard intraoperative monitoring was used for routine anesthetic and analgesic management without NOL index guidance.

Sponsors & Collaborators

  • Istinye University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-08-15
Primary Completion
2024-02-15
Completion
2024-02-15

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07720440 on ClinicalTrials.gov