A Real-World Study of Clinical Adoption, Treatment Patterns and Tolerability of Adjuvant Ribociclib in HR+/HER2- Early Breast Cancer Patients
NCT07710716 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 3000
Last updated 2026-07-17
Summary
The aim of this study is to assess the clinical adoption, treatment patterns, and safety of adjuvant ribociclib use in hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) early breast cancer (eBC) patients. This is a multi-country study using secondary real-world data sources.
Conditions
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Pharmaceuticals · Novartis Pharmaceuticals
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-09
- Primary Completion
- 2026-09-30
- Completion
- 2026-09-30
Countries
- Switzerland
Study Locations
More Related Trials
-
Comprehensive Analysis of Spatial, Temporal and Molecular Patterns of Ribociclib Efficacy and Resistance in Advanced Breast Cancer Patients
NCT05452213 ·Status: RECRUITING ·Phase: PHASE4
-
A Study of Real-World Treatment Patterns and Outcomes Among HR+/HER2- Metastatic Breast Cancer Patients Treated With First-Line CDK4/6 Inhibitors
NCT07512063 ·Status: COMPLETED
-
A Study of Ribociclib in Combination With Hormonal Therapy in HR+/HER2- Advanced or Metastatic Breast Cancer
NCT06075758 ·Status: COMPLETED
-
Ribociclib for HR-positive HER2-negative Metastatic Breast Cancer
NCT07164976 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Chemotherapy De-escalation in HR +, HER2-, Intermediate-risk Early Breast Cancer Treated With Adjuvant Ribociclib
NCT07237256 ·Status: RECRUITING ·Phase: PHASE3
-
A Real-world Study of Indian Patients With Advanced Breast Cancer Treated With Ribociclib
NCT07363434 ·Status: COMPLETED
-
A Study of Real-world Outcomes Among Patients Treated With Ribociclib
NCT07148505 ·Status: COMPLETED
-
Study of Ribociclib With Everolimus + Exemestane in HR+ HER2- Locally Advanced/Metastatic Breast Cancer Post Progression on CDK 4/6 Inhibitor.
NCT02732119 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase IIIB Study to Evaluate the Use of Capivasertib in Combination With Fulvestrant in Patients With Advanced Breast Cancer Who Have Relapsed/Progressed on ET and CDK4/6 Inhibitor Reflecting Real World Clinical Practice in Spain
NCT06764186 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Non-interventional Study for Kisqali (Ribociclib) in Combination With an Aromatase Inhibitor for Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer at High Risk of Recurrence
NCT06830720 ·Status: RECRUITING
-
A Study to Determine the Safety and Tolerability of Herceptin as an Adjuvant Therapy of Early Breast Cancer
NCT02443467 ·Status: COMPLETED
-
A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer
NCT07405801 ·Status: RECRUITING ·Phase: PHASE2
-
Description of Treatment Patterns and Description and Comparison of Healthcare Resource Utilization and Costs of Women With Metastatic HR+/HER2- Breast Cancer Treated With CDK4/6 Inhibitors
NCT05153135 ·Status: COMPLETED
-
A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC
NCT07002177 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Compassionate Use of Eribulin for the Treatment of Advanced Breast Cancer Refractory to All Other Marketed Therapies
NCT01142661 ·Status: COMPLETED ·Phase: NA
-
GW572016 In Patients With ErbB2 Over - Expressing Advanced Or Metastatic Breast Cancer
NCT00320411 ·Status: COMPLETED ·Phase: PHASE2
-
RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia
NCT06797531 ·Status: RECRUITING
-
Managed Access Program to Provide Access to Alpelisib for Patients With Advanced Breast Cancer
NCT04473040 ·Status: AVAILABLE
-
An Observational Study of Avastin (Bevacizumab) in Patients With HER2-metastatic or Locally Advanced Breast Cancer
NCT01461044 ·Status: COMPLETED
-
A Non-interventional Study for Women With HR-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer to Evaluate the Real-world Effectiveness of Treatment Algorithms Beginning With Ribociclib + AI/FUL, or With Endocrine Therapy or Chemotherapy as First Line Treatment
NCT06311383 ·Status: COMPLETED
-
Observational Retrospective Study to Assess the Use of Ribociclib in Patients With HR+, HER2- Metastatic Breast Cancer Treated With Chemotherapy
NCT06619704 ·Status: COMPLETED
-
Trastuzumab or Lapatinib Ditosylate in Treating Women With Early Breast Cancer
NCT01104571 ·Status: UNKNOWN ·Phase: PHASE3
-
Efficacy of Supplement Adjuvant Capecitabine in HR+/HER2- Breast Cancer Patients With High Risks
NCT05212454 ·Status: RECRUITING ·Phase: PHASE3
-
Eribulin in Combination With Capecitabine for Adjuvant Treatment in Estrogen Receptor-Positive Early Stage Breast Cancer
NCT01439282 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer
NCT07054190 ·Status: RECRUITING ·Phase: PHASE2