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Two Intravenous Doses of Ketamine in Reducing the Oculocardiac Reflex in Adult Patients Undergoing Ophthalmic Surgery

NCT07708740 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-07-16

No results posted yet for this study

Summary

This study aims to evaluate whether a lower dose of ketamine (0.5 mg/kg IV) may be as effective as a higher dose (0.75 mg/kg IV) in reducing oculocardiac reflex (OCR) incidence in adult patients undergoing ophthalmic surgery.

Conditions

  • Ketamine
  • Oculocardiac Reflex
  • Ophthalmic Surgery

Interventions

DRUG

0.5 mg/kg intravenous ketamine

Patients will receive 0.5 mg/kg intravenous ketamine hydrochloride.

DRUG

0.75 mg/kg intravenous ketamine

Patients will receive 0.75 mg/kg intravenous ketamine hydrochloride.

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-07-01
Primary Completion
2027-12-30
Completion
2027-12-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07708740 on ClinicalTrials.gov