Different Kinematics Within a Single-File System and Postoperative Pain

Summary

The goal of this clinical trial is to evaluating the influence of single file rotary system for root canal instrumentation using different kinematics on postoperative pain, the primary purpose: measuring post-operative pain by Numerical rating scale in a cohort population treatyed in Jordan Universoit of science and technology post graduate clinics with previously intittaed root canal treatement and could include any of the following: sex/gender, age groups (18-65 ), and healthy volunteers.

The main questions it aims to answer \[is/are:

* Is there any difference in postoperative pain after root canal treatment with different kinamtics
* Is this correlated with the level of cytokines measured taken from inside the canal system before and after treament whioch will be analyzed by the ELISA Kit for pain biomarkers.
* Is this related to in vitro debris extrusion, and can it validate previous research with the same methodology for debris extrusion measurement Researchers will compare 5 groups, which are Canal pro jeni, Continuous clockwise rotation (CCR), Optimum Torque Reverse (OTR), Forward reciprocating motion (REC), and Twisted Adaptive motion (TFA). All motions will be used with the One Curve file system Participants will report the level of pain after traatment level of cytokines will be measured by taking samples from the periapical area before, during, and after trematemtn

Conditions

• Root Canal Treatment
• Postoperative Pain
• Apical Periodontitis

Interventions

DEVICE

Twisted Adaptive motion (TFA)

motor that is capable of doing the adaptive motion

DEVICE

canal pro jeni

a new kinematics for root canal treatment

DEVICE

forward reciprocation

endodontic motor with the ability to change reciprocating angles and speed

DEVICE

continuous rotation

endodontic dental motor

DEVICE

Optimum Torque Reverse (OTR)

endodontic motor that is designed for rotate in Optimum Torque Reverse (OTR)

Sponsors & Collaborators

• Jordan University of Science and Technology

  lead OTHER

Principal Investigators

• Taher Mohammed Al Omari, BDS, MSc, JB Endo, M Endo RCSE · Jordan University of Science and Technology

• Aladdin Al Qudah, BDS, MSc, PhD · Jordan University of Science and Technology

• Lina Elsalem Elsalem, BDS, MSc, PhD · Jordan University of Science and Technology

• Rami AL Banna, BDS, JB Endo · Jordan University of Science and Technology

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2024-04-10

Primary Completion

2026-05-10

Completion

2026-09-10

FDA Device

Yes

Countries

• Jordan

Study Locations