Physical and Cognitive Outcomes After Post-Transplant Physiotherapy in Liver Transplant Recipients

NCT07694245 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 106

Last updated 2026-07-10

No results posted yet for this study

Summary

Liver transplantation is the most effective treatment for end-stage liver disease. However, many recipients continue to experience problems such as reduced physical function, impaired balance, fatigue, and cognitive difficulties even after successful transplantation. Although physiotherapy is commonly provided during the early postoperative period, its long-term benefits are not well understood.

This observational cross-sectional study evaluated the long-term physical and cognitive outcomes of adult liver transplant recipients approximately one year after transplantation. A total of 106 participants were included and divided into two groups according to whether they had participated in a routine post-transplant physiotherapy and rehabilitation program. Physical performance, balance, functional exercise capacity, cognitive function, and fatigue were assessed using standardized clinical outcome measures.

The study aimed to determine whether participation in a routine physiotherapy program was associated with better long-term functional outcomes after liver transplantation. The findings may help improve long-term rehabilitation strategies and support the integration of physiotherapy into routine multidisciplinary follow-up care for liver transplant recipients.

Conditions

  • Liver Transplantation (LT)
  • End-Stage Liver Disease

Interventions

OTHER

Routine Post-Transplant Physiotherapy

Participation in the routine postoperative physiotherapy and rehabilitation program provided after liver transplantation as part of standard clinical care. The program included breathing exercises, progressive mobilization, muscle strengthening, balance training, gait training, and functional exercises. Participants were not assigned to this intervention by the study protocol; the intervention had been completed before enrollment in this observational study.

Sponsors & Collaborators

  • Hasan Kalyoncu University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-27
Primary Completion
2026-06-15
Completion
2026-06-15

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07694245 on ClinicalTrials.gov