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Prevalence of Chapman Reflex Points in Medical Students and Their Association With Visceral Symptoms

NCT07691112 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 101

Last updated 2026-07-08

No results posted yet for this study

Summary

Chapman Reflex Points (CRPs) are small palpable nodules found within connective tissue that have traditionally been associated with dysfunction of internal organs and the autonomic nervous system. However, little is known about how commonly these findings occur in healthy individuals or whether they are associated with symptoms experienced by otherwise healthy people.

The purpose of this study is to determine the prevalence of Chapman Reflex Points in young healthy adults and to evaluate whether the presence and distribution of these points are associated with self-reported visceral symptoms. Participants complete a standardized health questionnaire regarding recent and recurrent symptoms and undergo a blinded physical examination of established Chapman Reflex Point locations performed by a trained investigator. The results of this study may improve understanding of the physiological mechanisms underlying Chapman Reflex Points and help clarify their potential role in preventive osteopathic assessment and early identification of altered autonomic, lymphatic, fascial, or neuroendocrine function.

Conditions

  • Healthy
  • Autonomic Nervous System Diseases
  • Lymphatic Diseases
  • Somatic Dysfunction
  • Chapman Reflex Points

Interventions

PROCEDURE

Chapman Reflex Point Examination

Participants underwent a standardized palpatory examination of established Chapman Reflex Point locations performed by a single trained investigator who was blinded to questionnaire responses. Consistent pressure application and examination duration were utilized to optimize reliability and reproducibility of palpatory findings. No therapeutic intervention, osteopathic manipulative treatment, medication administration, or other clinical intervention was provided as part of the study. Participants also completed a standardized health questionnaire assessing demographic characteristics, medical history, lifestyle factors, and recent or recurrent visceral symptoms.

Sponsors & Collaborators

  • The Touro College and University System

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-03-04
Primary Completion
2026-06-26
Completion
2026-06-27

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07691112 on ClinicalTrials.gov