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Effects of Whole Body Vibration on Quadriceps Function, Landing Biomechanics, and Performance in Individuals With ACL Reconstruction

NCT07681193 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2026-07-02

No results posted yet for this study

Summary

Individuals who undergo anterior cruciate ligament reconstruction (ACLR) are at heightened risk of secondary anterior cruciate ligament (ACL) injury (e.g. additional injury to the ACL in either knee). One of the primary physiological consequences of ACLR is the presence of quadriceps dysfunction (i.e. reduced activation and strength) which has been linked to altered gait and landing biomechanics. Aberrant landing biomechanics have been associated with an increased risk of both primary and secondary ACL injury, thus additional research is needed to evaluate the efficacy of treatments aimed to reduce quadriceps dysfunction and restore adequate landing biomechanics in attempts to reduce secondary ACL injury. Whole-body Vibration (WBV) has demonstrated success in improving quadriceps function and gait biomechanics in individuals with ACLR, however its effectiveness on landing biomechanics is unknown. To evaluate the acute effects of WBV on landing biomechanics in those with ACLR, a non-randomized crossover-controlled trial was conducted to determine if a single bout of WBV improved landing biomechanics greater than a control condition. Participants completed two separate testing sessions (separated by at least one week) in which measures of quadriceps function and landing biomechanics were assessed before and after either a control (no WBV) or WBV intervention. Separate linear mixed-effects models of post-test values for each dependent outcome were conducted with condition (control vs WBV) and limb (ACLR vs Uninvolved) as an interaction term, and each condition pre-test values and time post-ACLR as fixed effect covariates and a random effect of subject. The investigators expect to observe a significant improvement in landing biomechanics following WBV compared to the control condition.

Conditions

  • Anterior Cruciate Ligament Injuries
  • Anterior Cruciate Ligament Tear
  • ACL Injury
  • ACL Tear
  • Biomechanical Phenomena

Interventions

OTHER

Whole body vibration (WBV)

Participants will stand on a WBV platform in a mini-squat position while vibration is applied during six 60-second bouts with 2 minutes of rest between each bout. WBV will be delivered at an acceleration of 2g and a frequency of 30 Hz.

OTHER

Sham Whole body vibration

Participants will stand on a WBV platform in a mini-squat position during six 60-second bouts with 2 minutes of rest between each bout. No vibration will be applied.

Sponsors & Collaborators

  • University of North Carolina, Chapel Hill

    lead OTHER

Principal Investigators

  • Derek Dewig · University of North Carolina, Chapel Hill

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2022-04-22
Completion
2022-05-10

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07681193 on ClinicalTrials.gov