Characterization of Multi-Omics Landscapes and AI Pathological Prediction Model for Long-Term Survival in NSCLC Immunotherapy
NCT07668037 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 600
Last updated 2026-06-25
Summary
This study is a retrospective, multicenter, observational cohort study in patients with advanced or locally advanced non-small cell lung cancer (NSCLC). The aim of this study was to establish a long-term survival (LTS) versus short-term survival (STS) real-world cohort, to systematically characterize the multi-omics landscapes, and to develop and validate an artificial intelligence (AI) pathological prediction model based on routine H\&E-stained images for predicting immune microenvironment features and long-term survival outcomes following immunotherapy.
Conditions
- Non-Small Cell Carcinoma of Lung
- Immunotherapy
- Advanced Non-Small Cell Lung Cancer
Sponsors & Collaborators
-
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
lead OTHER
Principal Investigators
-
Jie Wang, MD, PhD · Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-01
- Primary Completion
- 2030-05-01
- Completion
- 2030-05-01
Countries
- China
Study Locations
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