Study on [14C]HMPL-453(FGFR Inhibitor) in Healthy Chinese Adult Male Subjects
NCT07644442 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2026-06-12
Summary
To evaluate the absorption, metabolism and excretion in healthy Chinese male subjects after a single oral dose of \[14C\]HMPL-453
Conditions
- Mass Balance Study
Interventions
- DRUG
-
HMPL-453
D1: 300 mg/200 µCi \[14C\] HMPL-453 Single dose
Sponsors & Collaborators
-
Hutchmed
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-02-26
- Primary Completion
- 2025-03-14
- Completion
- 2025-03-14
Countries
- China
Study Locations
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