Study on [14C]HMPL-453(FGFR Inhibitor) in Healthy Chinese Adult Male Subjects

NCT07644442 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 6

Last updated 2026-06-12

No results posted yet for this study

Summary

To evaluate the absorption, metabolism and excretion in healthy Chinese male subjects after a single oral dose of \[14C\]HMPL-453

Conditions

  • Mass Balance Study

Interventions

DRUG

HMPL-453

D1: 300 mg/200 µCi \[14C\] HMPL-453 Single dose

Sponsors & Collaborators

  • Hutchmed

    lead INDUSTRY

Study Design

Allocation
NA
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-02-26
Primary Completion
2025-03-14
Completion
2025-03-14

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07644442 on ClinicalTrials.gov