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Study on the Effect of Hyperbaric Oxygen Intervention on Relieving Sports Fatigue of Sailors

NCT07625696 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2026-07-30

No results posted yet for this study

Summary

1. Research Purpose Intensive training often causes autonomic nerve imbalance, poor microcirculation and slow fatigue recovery in elite sailing athletes. This study adopted 1.3 ATA mild hyperbaric oxygen with 28% oxygen concentration for a 6-week intervention. It aimed to explore whether mild hyperbaric oxygen can improve athletes' autonomic nerve function, microcirculation and fatigue-related biochemical indicators. Meanwhile, it intended to estimate the effect size, provide basis for future large-scale formal trials, and optimize fatigue recovery strategies for sailing athletes and other endurance athletes.
2. Study Population A total of 16 elite male sailing athletes were enrolled and randomly divided into two groups with 8 participants in each group.

Inclusion criteria: aged over 18 years; holding national first-class athlete certificate or above; participating in systematic sailing training at least 5 times a week with more than 5 years of professional training experience.

Those with cardiovascular diseases, absolute contraindications to hyperbaric oxygen, training suspension due to injury and other ineligible conditions were excluded.
3. Primary Outcome Measures Autonomic nerve function: Heart rate variability (HRV) indicators were tested to observe whether hyperbaric oxygen balances sympathetic and parasympathetic nerves and relieves training-induced autonomic disorder.

Microcirculation function: Measured muscle microcirculation blood flow velocity, capillary perfusion and thermal stimulation microvascular reserve capacity to evaluate the improvement of peripheral blood circulation.

Fatigue and biochemical biomarkers:

Routine blood indexes: red blood cell, hemoglobin, white blood cell; Exercise injury and metabolic indexes: creatine kinase (CK), blood urea nitrogen (BUN), testosterone and cortisol; Oxidative stress indexes: malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), to assess the body's oxidation-antioxidant status, inflammation level and fatigue recovery degree.

Conditions

  • Elite Male Sailing Athletes

Interventions

DEVICE

Mild Hyperbaric Oxygen Therapy

Participants receive mild hyperbaric oxygen therapy (mHBOT) in a hyperbaric chamber at 1.3 atmospheres absolute (ATA) with 28% oxygen concentration, for 60 minutes per session, 5 sessions per week over 6 weeks. All participants continue their standard sailing training regimen throughout the study.

Sponsors & Collaborators

  • Shanghai Research Institute of Sports Science

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-06-30
Primary Completion
2026-09-30
Completion
2026-10-29

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07625696 on ClinicalTrials.gov