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Circadian Feeding and Reciprocal Scent Intervention in NICU

NCT07622459 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2026-06-03

No results posted yet for this study

Summary

Objective: This study evaluated the effects of circadian-aligned feeding and reciprocal scent intervention on premature infants receiving mechanical ventilation and on postpartum depression levels in their mothers.

Methods: In this randomized controlled trial, 75 premature infants and their mothers were assigned to reciprocal scent, circadian feeding, or control groups (n=25 each). Interventions were applied for 21 days. Outcomes included time to weaning from mechanical ventilation, weight gain, hydration status, breast milk production, and maternal Edinburgh Postnatal Depression Scale (EPDS) scores.

Conditions

  • Prematurity
  • Mechanical Ventilation

Interventions

BEHAVIORAL

Reciprocal Scent Intervention

Maternal-infant reciprocal scent exposure combined with circadian-aligned feeding.

BEHAVIORAL

Circadian-Aligned Feeding

Breast milk feeding synchronized with the timing of milk expression according to circadian rhythm.

OTHER

Standard Care (in control arm)

Standard Care

Sponsors & Collaborators

  • Inonu University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Max Age
1 Year
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-10-01
Primary Completion
2025-11-01
Completion
2026-04-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07622459 on ClinicalTrials.gov