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Parasternal Block Versus Wound Infiltration for Pain After Median Sternotomy:A Salivary Opiorphin-Based Study

NCT07621744 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-06-02

No results posted yet for this study

Summary

This study evaluated the effects of parasternal block and wound site infiltration on postoperative pain in patients undergoing median sternotomy. Patients were allocated to receive parasternal block, wound site infiltration, or standard systemic analgesia. Salivary opiorphin levels and postoperative pain scores were assessed to compare analgesic effectiveness between the groups.

Conditions

  • Postoperative Pain
  • Cardiac Surgery
  • Median Sternotomy

Interventions

PROCEDURE

Parasternal blocks

Ultrasound-guided parasternal block was performed with local anesthetic before surgical incision.

PROCEDURE

Wound Site Infiltration

Local anesthetic infiltration was performed at the surgical wound site before surgical incision.

Sponsors & Collaborators

  • Ataturk University

    lead OTHER

Principal Investigators

  • Muhammed Enes Aydin, professor · Ataturk University Department of Anesthesiology and Reanimation

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-01
Primary Completion
2026-01-01
Completion
2026-01-12

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07621744 on ClinicalTrials.gov