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Postoperative Complications in Major Surgery

NCT07621198 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 364

Last updated 2026-06-02

No results posted yet for this study

Summary

The primary objective of this study is to develop and validate a multivariable risk prediction model for 30-day major postoperative complications and mortality in patients undergoing major surgery across participating international centers. Despite advancements in perioperative care, surgical complications remain a leading cause of global morbidity and preventable death, particularly in resource-limited or low- and middle-income country (LMIC) settings.

This study utilizes a prospective, multicenter, international cohort design. Data will be collected on patient-level risk factors (e.g., age, frailty, comorbidities), hospital-level infrastructure (e.g., nurse-to-patient ratios, rescue capacity), and perioperative safety processes (e.g., adherence to the WHO Surgical Safety Checklist). Patients will be followed prospectively for up to 30 days post-surgery. The collected data will be used to construct robust predictive models to identify individual patient risk and uncover actionable system-level factors to optimize surgical safety globally.

Conditions

  • Major Surgery

Interventions

OTHER

Patients with postoperative complications

Patients with observed complications (Clavien-Dindo \>3)

Sponsors & Collaborators

  • Hospital Departamental de Villavicencio

    lead OTHER

Principal Investigators

  • Norton Perez-Gutiérrez, MD · Hospital Departamental de Villavicencio

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-01
Primary Completion
2027-07-31
Completion
2027-08-30

Countries

  • Colombia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07621198 on ClinicalTrials.gov