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AI-empowered Nudge to Improve Colonoscopy Uptake (AINC)

NCT07612436 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1680

Last updated 2026-05-28

No results posted yet for this study

Summary

Colorectal cancer (CRC) ranks third in both incidence and mortality among all malignant tumors in China. Studies have shown that early screening can significantly reduce its incidence and mortality. Colonoscopy is the gold standard for CRC screening; however, compliance with colonoscopy among high-risk groups in China is very low. Artificial intelligence (AI)-assisted tools can provide real-time, personalized health education, and nudge strategies can help translate intent into action. This trial aims to evaluate the effectiveness of AI-empowered nudge for improving colonoscopy uptake among high-risk individuals aged 45 to 74 in China. It's a two-arm, pragmatic cluster randomized controlled trial. The main question it aims to answer is whether the AI-enabled personalized health education and nudge strategies improve colonoscopy adherence.

Participants will:

1. Be recruited and allocated into one of two groups according to the assigned clusters. Participants in one group will be invited to receive usual care. In addition to usual care, participants in the other group will receive AI-empowered nudge, featuring an AI chatbot providing real-time personalized responses and a nudge environment with default screening option.
2. Have their colonoscopy status checked at the end of trial.

Conditions

  • Colorectal Neoplasms
  • Colonoscopy

Interventions

BEHAVIORAL

AI-empowered nudge (AINC) strategy

A digital health education and behavioral nudge intervention. It utilizes an intelligent chatbot to provide real-time, personalized information about colonoscopy and implements a default screening mechanism to facilitate the translation from screening intention to behavior.

OTHER

Usual Care

Usual notification of screening results and opt-in appointment for colonoscopy.

Sponsors & Collaborators

  • Nantong Center for Disease Control and Prevention

    collaborator UNKNOWN

  • Fudan University

    lead OTHER

Principal Investigators

  • Zhiyuan Hou, PhD · Fudan University

Study Design

Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
74 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-05-30
Primary Completion
2026-10-01
Completion
2027-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07612436 on ClinicalTrials.gov