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Light Therapy to Improve Sleep in TBI: Sleep-active Biomarkers and Glymphatic Function

NCT07601841 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2026-05-22

No results posted yet for this study

Summary

This is a clinical trial designed to examine how improved sleep through morning bright light therapy is improving downstream key physiologic processes related to brain health, i.e., mitochondrial function, systemic inflammation, and glymphatic function. All proposed methodology is already approved in other IRB applications.

Conditions

  • Sleep
  • Phototherapy
  • Glymphatic System
  • Mitochondrial Dynamics
  • Brain Injuries, Traumatic
  • Inflammation

Interventions

DEVICE

Morning Bright Light Therapy

Exposure to bright light shortly after waking.

DEVICE

Negative Ion Generator Therapy

Exposure to negative ions shortly after waking.

Sponsors & Collaborators

  • Oregon Health and Science University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-12
Primary Completion
2028-12-12
Completion
2030-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07601841 on ClinicalTrials.gov