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Frozen Section Examination of Sentinel Lymph Nodes in Breast Cancer

NCT07591506 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 142

Last updated 2026-05-15

No results posted yet for this study

Summary

This prospective randomized clinical study evaluates the role of intraoperative frozen section examination of sentinel lymph nodes in patients with breast cancer. The study aims to determine whether frozen section assessment during surgery improves intraoperative decision-making and affects surgical management when compared with standard final pathological evaluation performed after surgery.

Conditions

  • Breast Neoplasms

Interventions

DIAGNOSTIC_TEST

Intraoperative Frozen Section Examination of Sentinel Lymph Node

Sentinel lymph nodes are rapidly transported to pathology without formaldehyde fixation and are evaluated intraoperatively by frozen section.

DIAGNOSTIC_TEST

Routine Postoperative Histopathological Evaluation of Sentinel Lymph Node

Sentinel lymph nodes are processed after formaldehyde fixation and evaluated with routine histopathology after surgery.

Sponsors & Collaborators

  • Izmir City Hospital

    lead OTHER_GOV

Principal Investigators

  • Orhan Ureyen, Prof. / MD · Izmir City Hospital / General Surgery

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-01
Primary Completion
2027-05-01
Completion
2027-05-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07591506 on ClinicalTrials.gov